Success Metrics

Clinical Success Rate
93.5%

Based on 29 completed trials

Completion Rate
94%(29/31)
Active Trials
65(50%)
Results Posted
66%(19 trials)
Terminated
2(2%)

Phase Distribution

Ph phase_1
28
22%
Ph phase_2
75
58%
Ph phase_4
2
2%
Ph not_applicable
3
2%
Ph phase_3
14
11%

Phase Distribution

28

Early Stage

75

Mid Stage

16

Late Stage

Phase Distribution122 total trials
Phase 1Safety & dosage
28(23.0%)
Phase 2Efficacy & side effects
75(61.5%)
Phase 3Large-scale testing
14(11.5%)
Phase 4Post-market surveillance
2(1.6%)
N/ANon-phased studies
3(2.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

93.5%

29 of 31 finished

Non-Completion Rate

6.5%

2 ended early

Currently Active

65

trials recruiting

Total Trials

129

all time

Status Distribution
Active(81)
Completed(29)
Terminated(2)
Other(17)

Detailed Status

Recruiting48
Completed29
Active, not recruiting17
Not yet recruiting15
unknown15
Suspended2

Development Timeline

Analytics

Development Status

Total Trials
129
Active
65
Success Rate
93.5%
Most Advanced
Phase 4

Trials by Phase

Phase 128 (23.0%)
Phase 275 (61.5%)
Phase 314 (11.5%)
Phase 42 (1.6%)
N/A3 (2.5%)

Trials by Status

enrolling_by_invitation11%
not_yet_recruiting1512%
recruiting4837%
active_not_recruiting1713%
suspended22%
terminated22%
completed2922%
unknown1512%

Recent Activity

Clinical Trials (129)

Showing 20 of 129 trialsScroll for more
NCT05356858Phase 2

An Open Label Study of the Effects and Safety of Zanubrutinib in NMOSDs Adult Patients

Terminated
NCT06742996Phase 3

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

Recruiting
NCT06073821Phase 3

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Active Not Recruiting
NCT06839053Phase 2

Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma

Recruiting
NCT05100862Phase 3

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Recruiting
NCT07141511Phase 1

A Study to Investigate the Relative Bioavailability and Food Effect of a Fixed-Dose Combination Tablet Containing Zanubrutinib and Sonrotoclax (BG-71332) in Healthy Adults

Completed
NCT07277231Phase 3

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Recruiting
NCT06637501Phase 2

A Study to Investigate Sonrotoclax Combined With Zanubrutinib Versus Zanubrutinib Alone in Participants With Previously Untreated Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT06859008Phase 1

Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Recruiting
NCT06634589Phase 1

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Recruiting
NCT04840602Phase 2

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

Recruiting
NCT05735834Phase 3

Comparison Between Rituximab Plus Zanubrutinib Versus Rituximab Monotherapy in Untreated SMZL Patients

Active Not Recruiting
NCT06561347Phase 2

Zanubrutinib, Bendamustine, Rituximab Prev. Untreated WM

Recruiting
NCT07271667Phase 2

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

Recruiting
NCT04277637Phase 1

Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies

Active Not Recruiting
NCT03824483Phase 2

Study of Zanubrutinib, Obinutuzumab, and Venetoclax in Patients With Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL)

Recruiting
NCT05068440Phase 2

Treatment of CD79B Mutant Relapsed/Refractory Diffuse Large B-Cell Lymphoma With Bruton Tyrosine Kinase Inhibitor Zanubrutinib

Completed
NCT07341191Phase 2

Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy

Not Yet Recruiting
NCT04458610Phase 2

Zanubrutinib and Rituximab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Active Not Recruiting
NCT03336333Phase 3

A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With Previously Untreated CLL or SLL

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
129