Success Metrics

Clinical Success Rate
93.5%

Based on 29 completed trials

Completion Rate
94%(29/31)
Active Trials
69(51%)
Results Posted
66%(19 trials)
Terminated
2(1%)

Phase Distribution

Ph phase_2
82
60%
Ph phase_4
2
1%
Ph not_applicable
3
2%
Ph phase_3
14
10%
Ph phase_1
28
21%

Phase Distribution

28

Early Stage

82

Mid Stage

16

Late Stage

Phase Distribution129 total trials
Phase 1Safety & dosage
28(21.7%)
Phase 2Efficacy & side effects
82(63.6%)
Phase 3Large-scale testing
14(10.9%)
Phase 4Post-market surveillance
2(1.6%)
N/ANon-phased studies
3(2.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

93.5%

29 of 31 finished

Non-Completion Rate

6.5%

2 ended early

Currently Active

69

trials recruiting

Total Trials

136

all time

Status Distribution
Active(89)
Completed(29)
Terminated(2)
Other(16)

Detailed Status

Recruiting49
Completed29
Active, not recruiting20
Not yet recruiting18
unknown15
Enrolling by invitation2

Development Timeline

Analytics

Development Status

Total Trials
136
Active
69
Success Rate
93.5%
Most Advanced
Phase 4

Trials by Phase

Phase 128 (21.7%)
Phase 282 (63.6%)
Phase 314 (10.9%)
Phase 42 (1.6%)
N/A3 (2.3%)

Trials by Status

unknown1511%
enrolling_by_invitation21%
recruiting4936%
suspended11%
completed2921%
not_yet_recruiting1813%
terminated21%
active_not_recruiting2015%

Recent Activity

Clinical Trials (136)

Showing 20 of 136 trialsScroll for more
NCT07739459Phase 2

Study of Zanubrutinib in Older Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL)

Not Yet Recruiting
NCT07734038Phase 2

Venetoclax Plus Zanubrutinib for the Treatment of Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma

Not Yet Recruiting
NCT04840602Phase 2

Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma

Recruiting
NCT06563505Phase 2

A Phase 2 Trial of Mosunetuzumab and Zanubrutinib for Patients With Relapsed/Refractory Marginal Zone Lymphoma

Recruiting
NCT06634589Phase 1

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Recruiting
NCT07277231Phase 3

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Recruiting
NCT05100862Phase 3

A Study of Zanubrutinib Plus Anti-CD20 Versus Lenalidomide Plus Rituximab in Participants With Relapsed/Refractory Follicular or Marginal Zone Lymphoma

Active Not Recruiting
NCT05707377Phase 2

A Study to Examine the Efficacy and Safety of Zanubrutinib Given to Adults With Primary Membranous Nephropathy

Active Not Recruiting
NCT06073821Phase 3

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Active Not Recruiting
NCT06849713Phase 2

Zanubrutinib, Obinutuzumab, Sonrotoclax (BOSon) or BGB-16673, Obinutuzumab, Sonrotoclax (DOSon) in TN CLL/SLL

Recruiting
NCT06742996Phase 3

A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

Recruiting
NCT05735834Phase 3

Comparison Between Rituximab Plus Zanubrutinib Versus Rituximab Monotherapy in Untreated SMZL Patients

Active Not Recruiting
NCT07717177Phase 2

AI-Driven Treatment Strategy vs ZR2 in Older Treatment-naive Patients With LBCL

Not Yet Recruiting
NCT06471738Phase 2

Combination of Zanubrutinib, Rituximab and Venetoclax in Patients With Previously Untreated Follicular Lymphoma

Recruiting
NCT05976763Phase 3

Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

Recruiting
NCT07341191Phase 2

Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy

Recruiting
NCT07638722Phase 2

Testing Mosunetuzumab Alone, With Zanubrutinib, or With Polatuzumab Vedotin for Treating Marginal Zone Lymphoma That Came Back or Didn't Get Better With Treatment

Not Yet Recruiting
NCT06637501Phase 2

A Study to Investigate Sonrotoclax Combined With Zanubrutinib Versus Zanubrutinib Alone in Participants With Previously Untreated Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT07690761Phase 2

Rituximab+ Zanubrutinib for Patients With Hairy Cell Leukemia and Hairy Cell Variant

Enrolling By Invitation
NCT04850495Phase 1

Zanubrutinib in Combination With R-PolaCHP (ZaR-PolaCHP) for Newly Diagnosed Diffuse Large B-Cell Lymphoma

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
136