Success Metrics

Clinical Success Rate
100.0%

Based on 3 completed trials

Completion Rate
100%(3/3)
Active Trials
16(67%)
Results Posted
0%(0 trials)

Phase Distribution

Ph phase_2
13
54%
Ph phase_3
5
21%
Ph phase_1
5
21%

Phase Distribution

5

Early Stage

13

Mid Stage

5

Late Stage

Phase Distribution23 total trials
Phase 1Safety & dosage
5(21.7%)
Phase 2Efficacy & side effects
13(56.5%)
Phase 3Large-scale testing
5(21.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

3 of 3 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

16

trials recruiting

Total Trials

24

all time

Status Distribution
Active(20)
Completed(3)
Other(1)

Detailed Status

Recruiting15
Not yet recruiting4
Completed3
Active, not recruiting1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
24
Active
16
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 15 (21.7%)
Phase 213 (56.5%)
Phase 35 (21.7%)

Trials by Status

not_yet_recruiting417%
active_not_recruiting14%
unknown14%
completed313%
recruiting1563%

Recent Activity

Clinical Trials (24)

Showing 20 of 24 trialsScroll for more
NCT06043427Phase 2

Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal Adenocarcinoma

Recruiting
NCT06324357Phase 1

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Recruiting
NCT07290985Phase 2

AACR Adaptive Biomarker-Driven Organ Preservation Trial in Gastroesophageal Adenocarcinomas

Recruiting
NCT05152147Phase 3

A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gastric and Esophageal Cancers

Active Not Recruiting
NCT07102381Phase 2

A Phase 2 Neoadjuvant Study of Zanidatamab in Combination With Chemotherapy in Participants With HER2-positive Breast Cancer

Recruiting
NCT06282575Phase 3

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

Recruiting
NCT06695845Phase 2

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Recruiting
NCT07685704Phase 2

Zanidatamab Combined With Chemotherapy as Neoadjuvant/Conversion Therapy for HER2-Positive (IHC 3+ or IHC 2+) Advanced Gastric or Gastroesophageal Junction Adenocarcinoma: a Phase II Open-Label Study

Not Yet Recruiting
NCT05027139Phase 1

A Study of Zanidatamab (ZW25) With Evorpacept (ALX148) in Patients With Advanced HER2-expressing Cancer

Completed
NCT07176312Phase 2

Zanidatamab in Combination With Pembrolizumab and Chemotherapy in HER2 and PD-L1 Positive Metastatic Gastroesophageal Adenocarcinoma (GEA) Patients

Recruiting
NCT07631871Phase 2

An Exploratory Study of Zanidatamab in HER2-positive Advanced Tumor After at Least One Line of Standard Therapy

Not Yet Recruiting
NCT05035836Phase 2

A Phase 2 Single-Arm Open-Label Pilot Trial Evaluating Zanidatamab (ZW25) in Patients With Early Stage HER2/Neu Positive (HER2+) Breast Cancer (BC)

Recruiting
NCT04164199Phase 3

Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With Advanced Malignancies

Completed
NCT05615818Phase 3

Personalized Medicine for Advanced Biliary Cancer Patients

Recruiting
NCT01042379Phase 2

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

Recruiting
NCT07494448Phase 1

Phase Ib/II Study of Zanidatamab Plus Tucatinib and Chemotherapy in HER2-Positive Advanced Breast Cancer

Not Yet Recruiting
NCT07405476Phase 2

Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment

Recruiting
NCT06435429Phase 3

A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer

Recruiting
NCT07296705Phase 2

Neoadjuvant Zanidatamab + Tislelizumab + Chemotherapy for Selective Bladder Preservation in HER2-Positive MIBC

Recruiting
NCT07192068Phase 2

Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene.

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
24