Success Metrics

Clinical Success Rate
83.3%

Based on 10 completed trials

Completion Rate
83%(10/12)
Active Trials
0(0%)
Results Posted
30%(3 trials)
Terminated
2(17%)

Phase Distribution

Ph phase_1
7
58%
Ph phase_2
5
42%

Phase Distribution

7

Early Stage

5

Mid Stage

0

Late Stage

Phase Distribution12 total trials
Phase 1Safety & dosage
7(58.3%)
Phase 2Efficacy & side effects
5(41.7%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

83.3%

10 of 12 finished

Non-Completion Rate

16.7%

2 ended early

Currently Active

0

trials recruiting

Total Trials

12

all time

Status Distribution
Completed(10)
Terminated(2)

Detailed Status

Completed10
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
12
Active
0
Success Rate
83.3%
Most Advanced
Phase 2

Trials by Phase

Phase 17 (58.3%)
Phase 25 (41.7%)

Trials by Status

terminated217%
completed1083%

Recent Activity

0 active trials
Showing 5 of 12
completedphase_2

Trial of a Gastrin Receptor Antagonist in Barrett's Esophagus

NCT01298999
completedphase_2

YF476 in Barrett's Esophagus

NCT02597712
terminatedphase_2

YF476 and Type II Gastric Carcinoids

NCT02454075
completedphase_2

YF476 and Type I Gastric Carcinoids

NCT01339169
terminatedphase_2

YF476 and Type I Gastric Carcinoids (Norway)

NCT01444014
View all 12 trials

Clinical Trials (12)

Showing 12 of 12 trials
NCT01298999Phase 2

Trial of a Gastrin Receptor Antagonist in Barrett's Esophagus

Completed
NCT02597712Phase 2

YF476 in Barrett's Esophagus

Completed
NCT02454075Phase 2

YF476 and Type II Gastric Carcinoids

Terminated
NCT01339169Phase 2

YF476 and Type I Gastric Carcinoids

Completed
NCT01444014Phase 2

YF476 and Type I Gastric Carcinoids (Norway)

Terminated
NCT01699113Phase 1

Effects of YF476 and Rabeprazole on Gastric Function

Completed
NCT01601418Phase 1

Effect of Single Doses of YF476 on Stomach Acidity

Completed
NCT01601405Phase 1

Effect of Repeated Doses of YF476 on Stomach Acidity

Completed
NCT01599858Phase 1

Effect of Repeated Doses of YF476, Omeprazole and Placebo on Stomach Acidity in Healthy Volunteers

Completed
NCT01597674Phase 1

Effect of 5, 10 or 25 mg of YF476 Daily for 14 Days on Stomach Acidity in Healthy Volunteers

Completed
NCT01538797Phase 1

Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States

Completed
NCT01538784Phase 1

Safety, Tolerability and Pharmacokinetics of Single Rising Doses of YF476, a Gastrin Antagonist, in Healthy Men

Completed

All 12 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
12