Success Metrics

Clinical Success Rate
97.5%

Based on 39 completed trials

Completion Rate
98%(39/40)
Active Trials
9(15%)
Results Posted
59%(23 trials)
Terminated
1(2%)

Phase Distribution

Ph phase_2
4
6%
Ph phase_3
13
21%
Ph phase_4
21
34%
Ph not_applicable
7
11%
Ph phase_1
8
13%
Ph early_phase_1
2
3%

Phase Distribution

10

Early Stage

4

Mid Stage

34

Late Stage

Phase Distribution55 total trials
Early Phase 1First-in-human
2(3.6%)
Phase 1Safety & dosage
8(14.5%)
Phase 2Efficacy & side effects
4(7.3%)
Phase 3Large-scale testing
13(23.6%)
Phase 4Post-market surveillance
21(38.2%)
N/ANon-phased studies
7(12.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

95.1%

39 of 41 finished

Non-Completion Rate

4.9%

2 ended early

Currently Active

9

trials recruiting

Total Trials

62

all time

Status Distribution
Active(16)
Completed(39)
Terminated(2)
Other(5)

Detailed Status

Completed39
Recruiting8
Not yet recruiting6
unknown5
Enrolling by invitation1
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
62
Active
9
Success Rate
97.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (3.6%)
Phase 18 (14.5%)
Phase 24 (7.3%)
Phase 313 (23.6%)
Phase 421 (38.2%)
N/A7 (12.7%)

Trials by Status

not_yet_recruiting610%
enrolling_by_invitation12%
terminated12%
recruiting813%
active_not_recruiting12%
unknown58%
withdrawn12%
completed3963%

Recent Activity

Clinical Trials (62)

Showing 20 of 62 trialsScroll for more
NCT07731542Not Applicable

Vonoprazan Alone vs With Itopride for Functional Dyspepsia: The VIVA Trial

Recruiting
NCT06851559Phase 2

A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks

Active Not Recruiting
NCT07624422Phase 4

Vonoprazan High-Dose Dual VS Levofloxacin Concomitant

Not Yet Recruiting
NCT07608536Phase 3

Comparison of Rabeprazole and Vonoprazan in the Prevention of Post-endoscopic Variceal Ligation Ulcer in Patients With Cirrhosis

Not Yet Recruiting
NCT07563491Not Applicable

Comparison of Esomeprazole Versus Vonoprazan in Gastroesophageal Reflux Disease

Completed
NCT06955520Not Applicable

Vonaprazan Versus Esomeprazole for Healing of LA Grade B or Higher Esophagitis After POEM

Recruiting
NCT06561711Phase 4

Optimization of Minocycline for Helicobacter Pylori Rescue Treatment

Completed
NCT05582174Phase 4

PPI Infusion Versus Oral Acid Pump Inhibitors for Bleeding Peptic Ulcers

Recruiting
NCT06953986Not Applicable

A Randomized, Three-Arm Study Comparing Vonaprazan 10 mg, Vonaprazan 20 mg, and Esomeprazole 40 mg for the Healing of LA Grade B or Higher Reflux Esophagitis at 8 Weeks

Recruiting
NCT06340724Phase 3

Banxiaxiexin Decoction Combined With Vonoprazan-Amoxicillin Dual Therapy in H. Pylori Eradication

Completed
NCT07242456Phase 2

Head-to-head Study of Tegoprazan 50 mg BID Plus Amoxicillin 1 g TID vs. Vonoprazan 20 mg BID Plus Amoxicillin 1 g TID for H. Pylori Eradication

Recruiting
NCT05874544Phase 4

Rescue Therapy for Helicobacter Pylori Infection

Completed
NCT07068607Phase 4

Efficacy Comparison of Vonoprazan Combined With Different Antibiotics in Dual Therapy for Helicobacter Pylori Eradication: A Prospective, Randomized Controlled Clinical Trial

Recruiting
NCT06168084Phase 4

Helicobacter Rescue Therapy With Vonorazon and Amoxicillin Dual Therapy Versus Bismuth-containing Quadruple Therapy

Completed
NCT06514274Phase 4

Study on The Efficacy and Safety of Vonoprazan-containing Berberine Triple Therapy in Helicobacter Pylori First-Line Eradication

Completed
NCT03214081

Special Drug Use Surveillance of Vonoprazan for "Maintenance Therapy of Reflux Esophagitis: Long-term Use"

Completed
NCT06660342

A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring

Recruiting
NCT04720781Not Applicable

The Need of Revisiting to an Outpatient Clinic After the Prescription of Vonoprazan or Esomeprazole

Completed
NCT06292546Not Applicable

The Effects of High-dose Dual Therapy With Probiotics on Gut Microbiota for Helicobacter Pylori Rescue Treatment

Completed
NCT05343364Phase 1

A Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of Vonoprazan in Adolescents With Symptomatic Gastroesophageal Reflux Disease

Completed

Drug Details

Intervention Type
DRUG
Total Trials
62