Success Metrics

Clinical Success Rate
71.4%

Based on 10 completed trials

Completion Rate
71%(10/14)
Active Trials
1(6%)
Results Posted
70%(7 trials)
Terminated
4(24%)

Phase Distribution

Ph phase_1
2
12%
Ph phase_4
1
6%
Ph phase_3
8
47%
Ph phase_2
5
29%

Phase Distribution

2

Early Stage

5

Mid Stage

9

Late Stage

Phase Distribution16 total trials
Phase 1Safety & dosage
2(12.5%)
Phase 2Efficacy & side effects
5(31.3%)
Phase 3Large-scale testing
8(50.0%)
Phase 4Post-market surveillance
1(6.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

66.7%

10 of 15 finished

Non-Completion Rate

33.3%

5 ended early

Currently Active

1

trials recruiting

Total Trials

17

all time

Status Distribution
Active(1)
Completed(10)
Terminated(5)
Other(1)

Detailed Status

Completed10
Terminated4
Withdrawn1
Recruiting1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
17
Active
1
Success Rate
71.4%
Most Advanced
Phase 4

Trials by Phase

Phase 12 (12.5%)
Phase 25 (31.3%)
Phase 38 (50.0%)
Phase 41 (6.3%)

Trials by Status

terminated424%
completed1059%
withdrawn16%
recruiting16%
unknown16%

Recent Activity

1 active trials
Showing 5 of 17
terminatedphase_3

Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis

NCT05288855
terminatedphase_3

Long-Term Voclosporin Treatment in Adolescent and Pediatric Subjects With Lupus Nephritis

NCT05962788
recruitingphase_4

Safety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of Proliferative Forms of Lupus Glomerulopathy: Synergy Trial

NCT07225387
terminatedphase_2

Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus

NCT05306873
unknown

Special Access for the Use of Voclosporin for Kidney Transplantation

NCT01236287
View all 17 trials

Clinical Trials (17)

Showing 17 of 17 trials
NCT05288855Phase 3

Voclosporin in Adolescent and Pediatric Subjects With Lupus Nephritis

Terminated
NCT05962788Phase 3

Long-Term Voclosporin Treatment in Adolescent and Pediatric Subjects With Lupus Nephritis

Terminated
NCT07225387Phase 4

Safety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of Proliferative Forms of Lupus Glomerulopathy: Synergy Trial

Recruiting
NCT05306873Phase 2

Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus

Terminated
NCT01236287

Special Access for the Use of Voclosporin for Kidney Transplantation

Unknown
NCT04701528Phase 2

Anti-Viral Effects of Voclosporin in COVID-19 Positive Kidney Transplant Recipients

Completed
NCT03021499Phase 3

Aurinia Renal Response in Active Lupus With Voclosporin

Completed
NCT00244842Phase 3

Randomized Placebo-controlled Study of ISA247 in Plaque Psoriasis

Completed
NCT03597464Phase 3

Aurinia Renal Assessments 2: Aurinia Renal Response in Lupus With Voclosporin

Completed
NCT05306379Phase 1

Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin

Completed
NCT03598036Phase 2

Dose-Exploration Evaluating the Efficacy and Safety of Voclosporin in Subjects With Focal Segmental Glomerulosclerosis

Terminated
NCT02949973Phase 2

Aurinia Early Urinary Protein Reduction Predicts Response

Completed
NCT02949999Phase 1

Voclosporin in Healthy Japanese Volunteers

Completed
NCT01586845Phase 3

Safety and Efficacy Study of Voclosporin and Tacrolimus in Transplantation

Withdrawn
NCT00270634Phase 2

Study of ISA247 (Voclosporin) in De Novo Renal Transplantation

Completed
NCT00408187Phase 3

Randomized, Placebo and Ciclosporin Controlled Study of ISA247 in Plaque Psoriasis Patients

Completed
NCT00258713Phase 3

A 36-Week Extension to Protocol ISA04-03

Completed

All 17 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
17