Success Metrics

Clinical Success Rate
72.7%

Based on 157 completed trials

Completion Rate
73%(157/216)
Active Trials
138(32%)
Results Posted
97%(153 trials)
Terminated
59(14%)

Phase Distribution

Ph early_phase_1
6
1%
Ph phase_3
92
21%
Ph phase_2
191
44%
Ph phase_1
104
24%
Ph not_applicable
13
3%
Ph phase_4
24
6%

Phase Distribution

110

Early Stage

191

Mid Stage

116

Late Stage

Phase Distribution430 total trials
Early Phase 1First-in-human
6(1.4%)
Phase 1Safety & dosage
104(24.2%)
Phase 2Efficacy & side effects
191(44.4%)
Phase 3Large-scale testing
92(21.4%)
Phase 4Post-market surveillance
24(5.6%)
N/ANon-phased studies
13(3.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

69.5%

157 of 226 finished

Non-Completion Rate

30.5%

69 ended early

Currently Active

138

trials recruiting

Total Trials

433

all time

Status Distribution
Active(155)
Completed(157)
Terminated(69)
Other(52)

Detailed Status

Completed157
Recruiting78
Active, not recruiting60
Terminated59
unknown47
Not yet recruiting15

Development Timeline

Analytics

Development Status

Total Trials
433
Active
138
Success Rate
72.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (1.4%)
Phase 1104 (24.2%)
Phase 2191 (44.4%)
Phase 392 (21.4%)
Phase 424 (5.6%)
N/A13 (3.0%)

Trials by Status

suspended51%
completed15736%
terminated5914%
withdrawn102%
unknown4711%
active_not_recruiting6014%
enrolling_by_invitation20%
recruiting7818%
not_yet_recruiting153%

Recent Activity

Clinical Trials (433)

Showing 20 of 433 trialsScroll for more
NCT06045247Phase 2

Phase 2 Trial of Epcoritamab in Combination With Rituximab-mini CVP for Older Unfit/Frail Patients or Anthracycline-Ineligible Adult Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma

Recruiting
NCT06717347Phase 3

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

Recruiting
NCT04043494Phase 3

International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma

Recruiting
NCT04803201Phase 2

Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

Suspended
NCT06191744Phase 3

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma

Recruiting
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT06124157Phase 2

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

Recruiting
NCT05304585Phase 3

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

Recruiting
NCT05848765Phase 2

Relapsed Follicular Lymphoma Randomised Trial Against Standard ChemoTherapy

Recruiting
NCT02724579Phase 2

Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma

Active Not Recruiting
NCT05382338Phase 3

A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing Loss

Recruiting
NCT04322318Phase 2

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Recruiting
NCT06647953Phase 3

Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

Recruiting
NCT04978584Phase 2

Rituximab, Lenalidomide, Acalabrutinib, Tafasitamab Alone and With Combination Chemotherapy for the Treatment of Newly Diagnosed Non-germinal Center Diffuse Large B-Cell Lymphoma, Smart Stop Study

Active Not Recruiting
NCT06401330Phase 3

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Recruiting
NCT06564038Phase 1

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

Recruiting
NCT02981628Phase 2

Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

Recruiting
NCT02101853Phase 3

Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT02112916Phase 3

Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
433