Success Metrics

Clinical Success Rate
59.9%

Based on 103 completed trials

Completion Rate
60%(103/172)
Active Trials
316(55%)
Results Posted
79%(81 trials)
Terminated
69(12%)

Phase Distribution

Ph phase_2
226
39%
Ph phase_3
53
9%
Ph phase_1
253
44%
Ph not_applicable
19
3%
Ph phase_4
6
1%
Ph early_phase_1
5
1%

Phase Distribution

258

Early Stage

226

Mid Stage

59

Late Stage

Phase Distribution562 total trials
Early Phase 1First-in-human
5(0.9%)
Phase 1Safety & dosage
253(45.0%)
Phase 2Efficacy & side effects
226(40.2%)
Phase 3Large-scale testing
53(9.4%)
Phase 4Post-market surveillance
6(1.1%)
N/ANon-phased studies
19(3.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

52.0%

103 of 198 finished

Non-Completion Rate

48.0%

95 ended early

Currently Active

316

trials recruiting

Total Trials

577

all time

Status Distribution
Active(352)
Completed(103)
Terminated(95)
Other(27)

Detailed Status

Recruiting198
Active, not recruiting118
Completed103
Terminated69
Not yet recruiting35
Withdrawn26

Development Timeline

Analytics

Development Status

Total Trials
577
Active
316
Success Rate
59.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 15 (0.9%)
Phase 1253 (45.0%)
Phase 2226 (40.2%)
Phase 353 (9.4%)
Phase 46 (1.1%)
N/A19 (3.4%)

Trials by Status

not_yet_recruiting356%
recruiting19834%
suspended61%
enrolling_by_invitation10%
terminated6912%
unknown214%
active_not_recruiting11820%
withdrawn265%
completed10318%

Recent Activity

Clinical Trials (577)

Showing 20 of 577 trialsScroll for more
NCT07581002Phase 2

A Study to Assess Adverse Events and Change in Disease Activity When Intravenous (IV) Pivekimab Sunirine is Given in Combination With Oral Venetoclax and IV or Subcutaneous Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML)

Recruiting
NCT07437950Phase 2

Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Recruiting
NCT04447716Phase 1

An Early Phase Study of Venetoclax, Lenalidomide, and Rituximab/Hyaluronidase in Slow-Growing Lymphomas That Have Come Back After Treatment or Have Not Responded to Treatment

Active Not Recruiting
NCT03872180Phase 2

Bendamustine, Obinutuzumab, and Venetoclax in Patients With Untreated Mantle Cell Lymphoma

Active Not Recruiting
NCT07713732Phase 1

TLN-499 in Combination With Venetoclax in Patients With Relapsed/Refractory Solid Tumors

Recruiting
NCT05554419Phase 2

Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)

Not Yet Recruiting
NCT03701282Phase 3

Assessing the Ability of Combination Treatment With Venetoclax to Permit Time Limited Therapy in Chronic Lymphocytic Leukemia

Active Not Recruiting
NCT06649812Phase 2

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Recruiting
NCT06419634Phase 1

Study of BMS-986497 (ORM-6151) as a Monotherapy, in Double and Triple Combination With Azacitidine and Venetoclax in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Terminated
NCT06917911Phase 2

Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)

Recruiting
NCT07231952Phase 2

A Study of Pirtobrutinib, Venetoclax, and Rituximab in People With Waldenström's Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)

Recruiting
NCT04269902Phase 3

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Recruiting
NCT04560322Phase 2

Venetoclax-Obinutuzumab +/- Acalabrutinib in R/R CLL

Active Not Recruiting
NCT07847957Phase 1

Roginolisib Plus Obinutuzumab + Venetoclax in R/R CLL

Not Yet Recruiting
NCT06763341Phase 1

A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Recruiting
NCT07478991Phase 3

Azacytidine, Venetoclax Plus Minus Quizartinib for First Line Older/Unfit AML Patients (VENP-A-QUI)

Recruiting
NCT05768711Phase 2

Azacitidine Combined With Venetoclax in Patients With Higher-risk Chronic Myelomonocytic Leukemia (AVENHIR)

Active Not Recruiting
NCT06524375Phase 2

A Study to Evaluate the Effect of Venetoclax on Participants Receiving a Covalent Bruton's Tyrosine Kinase Inhibitor (cBTKi) for First-line Chronic Lymphocytic Leukemia (1L CLL) to Achieve Deep Durable Remissions to Allow Off-treatment Period

Active Not Recruiting
NCT03462719Phase 3

A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Active Not Recruiting
NCT06073821Phase 3

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
577