Success Metrics

Clinical Success Rate
59.4%

Based on 92 completed trials

Completion Rate
59%(92/155)
Active Trials
305(55%)
Results Posted
84%(77 trials)
Terminated
63(11%)

Phase Distribution

Ph not_applicable
17
3%
Ph phase_1
244
44%
Ph phase_3
51
9%
Ph phase_4
5
1%
Ph early_phase_1
5
1%
Ph phase_2
214
39%

Phase Distribution

249

Early Stage

214

Mid Stage

56

Late Stage

Phase Distribution536 total trials
Early Phase 1First-in-human
5(0.9%)
Phase 1Safety & dosage
244(45.5%)
Phase 2Efficacy & side effects
214(39.9%)
Phase 3Large-scale testing
51(9.5%)
Phase 4Post-market surveillance
5(0.9%)
N/ANon-phased studies
17(3.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

51.1%

92 of 180 finished

Non-Completion Rate

48.9%

88 ended early

Currently Active

305

trials recruiting

Total Trials

551

all time

Status Distribution
Active(342)
Completed(92)
Terminated(88)
Other(29)

Detailed Status

Recruiting205
Active, not recruiting100
Completed92
Terminated63
Not yet recruiting36
Withdrawn25

Development Timeline

Analytics

Development Status

Total Trials
551
Active
305
Success Rate
59.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 15 (0.9%)
Phase 1244 (45.5%)
Phase 2214 (39.9%)
Phase 351 (9.5%)
Phase 45 (0.9%)
N/A17 (3.2%)

Trials by Status

unknown224%
enrolling_by_invitation10%
recruiting20537%
not_yet_recruiting367%
active_not_recruiting10018%
completed9217%
suspended71%
terminated6311%
withdrawn255%

Recent Activity

Clinical Trials (551)

Showing 20 of 551 trialsScroll for more
NCT04140487Phase 1

Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent/Refractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Recruiting
NCT06073821Phase 3

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Active Not Recruiting
NCT06522386Phase 2

GATE1: A Multicenter Phase II Study of Pirtobrutinib, Rituximab and Venetoclax Combination Therapy for Patients With Previously Untreated Mantle Cell Lymphoma

Active Not Recruiting
NCT07454226Not Applicable

ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALL

Not Yet Recruiting
NCT07490288Not Applicable

Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML

Not Yet Recruiting
NCT06782542Phase 2

Olutasidenib, Venetoclax, and Azacitidine in IDH1 Mutated Newly Diagnosed Acute Myeloid Leukemia Patients Eligible for Intensive Induction Chemotherapy

Recruiting
NCT07493161Not Applicable

Chemotherapy With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALL

Not Yet Recruiting
NCT06649812Phase 2

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT06846671Phase 3

A Study of BGB-16673 Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors

Recruiting
NCT05554393Phase 2

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Recruiting
NCT04269902Phase 3

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Recruiting
NCT02250937Phase 2

Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

Active Not Recruiting
NCT07277231Phase 3

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

Recruiting
NCT06943872Phase 3

A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

Recruiting
NCT04975919Phase 2

Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Active Not Recruiting
NCT05529069Phase 2

Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients

Recruiting
NCT07032727Phase 2

Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT05554406Phase 2

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
551