Success Metrics

Clinical Success Rate
60.1%

Based on 101 completed trials

Completion Rate
60%(101/168)
Active Trials
313(55%)
Results Posted
80%(81 trials)
Terminated
67(12%)

Phase Distribution

Ph phase_1
250
44%
Ph phase_2
225
39%
Ph not_applicable
19
3%
Ph phase_3
53
9%
Ph phase_4
5
1%
Ph early_phase_1
5
1%

Phase Distribution

255

Early Stage

225

Mid Stage

58

Late Stage

Phase Distribution557 total trials
Early Phase 1First-in-human
5(0.9%)
Phase 1Safety & dosage
250(44.9%)
Phase 2Efficacy & side effects
225(40.4%)
Phase 3Large-scale testing
53(9.5%)
Phase 4Post-market surveillance
5(0.9%)
N/ANon-phased studies
19(3.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

52.1%

101 of 194 finished

Non-Completion Rate

47.9%

93 ended early

Currently Active

313

trials recruiting

Total Trials

572

all time

Status Distribution
Active(350)
Completed(101)
Terminated(93)
Other(28)

Detailed Status

Recruiting202
Active, not recruiting111
Completed101
Terminated67
Not yet recruiting36
Withdrawn26

Development Timeline

Analytics

Development Status

Total Trials
572
Active
313
Success Rate
60.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 15 (0.9%)
Phase 1250 (44.9%)
Phase 2225 (40.4%)
Phase 353 (9.5%)
Phase 45 (0.9%)
N/A19 (3.4%)

Trials by Status

terminated6712%
unknown214%
completed10118%
suspended71%
withdrawn265%
recruiting20235%
enrolling_by_invitation10%
not_yet_recruiting366%
active_not_recruiting11119%

Recent Activity

Clinical Trials (572)

Showing 20 of 572 trialsScroll for more
NCT06317649Phase 2

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Recruiting
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT05554406Phase 2

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

Recruiting
NCT07762508Not Applicable

A Prospective Single-Arm Study of VABu Conditioning Regimen in Allo-HSCT for Low-Performance or High-Comorbidity AML Patients in CR1

Not Yet Recruiting
NCT06917911Phase 2

Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)

Recruiting
NCT06311227Phase 2

Venetoclax for the Treatment of Patients With Relapsed Hairy Cell Leukemia

Recruiting
NCT03223610Phase 1

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

Recruiting
NCT04269902Phase 3

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Recruiting
NCT02942290Phase 1

A Study Evaluating Venetoclax in Combination With Azacitidine in Participants With Treatment-Naïve Higher-Risk Myelodysplastic Syndromes (MDS)

Completed
NCT07311746Phase 1

Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic Leukemia

Recruiting
NCT07513129Phase 1

Venetoclax, Dexamethasone, Bortezomib, and Daratumumab For The Treatment Of Adolescent And Young Adults With Relapsed Or Refractory T-Cell Acute Lymphoblastic Leukemia And T-cell Acute Lymphoblastic Lymphoma

Recruiting
NCT02756897Phase 2

Venetoclax and Ibrutinib in Treating Patients With Chronic or Small Lymphocytic Leukemia

Active Not Recruiting
NCT05554393Phase 2

Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

Recruiting
NCT04708054Phase 2

Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS

Recruiting
NCT06672146Phase 2

Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)

Recruiting
NCT03128879Phase 2

Venetoclax With Ibrutinib or Acalabrutinib in Pts. With High-risk CLL

Active Not Recruiting
NCT02846623Phase 2

Atezolizumab, Obinutuzumab, and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Relapsed or Refractory Richter Syndrome

Active Not Recruiting
NCT07495631Not Applicable

Pediatric-Inspired Regimen Combined With Venetoclax and Immunotherapy for Adult Ph-Negative Acute Lymphoblastic Leukemia

Recruiting
NCT07754799Phase 2

A Randomized Phase II Selection Trial of Venetoclax-Based Induction Intensity in Newly Diagnosed Acute Myeloid Leukemia

Not Yet Recruiting
NCT07131059Not Applicable

MRD-positive AML Clinical Study

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
572