Success Metrics

Clinical Success Rate
77.2%

Based on 115 completed trials

Completion Rate
77%(115/149)
Active Trials
23(11%)
Results Posted
70%(81 trials)
Terminated
34(16%)

Phase Distribution

Ph phase_3
45
21%
Ph early_phase_1
2
1%
Ph phase_1
19
9%
Ph not_applicable
34
16%
Ph phase_2
45
21%
Ph phase_4
57
27%

Phase Distribution

21

Early Stage

45

Mid Stage

102

Late Stage

Phase Distribution202 total trials
Early Phase 1First-in-human
2(1.0%)
Phase 1Safety & dosage
19(9.4%)
Phase 2Efficacy & side effects
45(22.3%)
Phase 3Large-scale testing
45(22.3%)
Phase 4Post-market surveillance
57(28.2%)
N/ANon-phased studies
34(16.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

73.7%

115 of 156 finished

Non-Completion Rate

26.3%

41 ended early

Currently Active

23

trials recruiting

Total Trials

214

all time

Status Distribution
Active(29)
Completed(115)
Terminated(41)
Other(29)

Detailed Status

Completed115
Terminated34
unknown28
Recruiting18
Withdrawn7
Not yet recruiting6

Development Timeline

Analytics

Development Status

Total Trials
214
Active
23
Success Rate
77.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (1.0%)
Phase 119 (9.4%)
Phase 245 (22.3%)
Phase 345 (22.3%)
Phase 457 (28.2%)
N/A34 (16.8%)

Trials by Status

unknown2813%
active_not_recruiting52%
terminated3416%
not_yet_recruiting63%
withdrawn73%
recruiting188%
suspended10%
completed11554%

Recent Activity

Clinical Trials (214)

Showing 20 of 214 trialsScroll for more
NCT02216227Not Applicable

Checklist to Prevent MRSA Surgical Site Infections

Completed
NCT07490054Phase 1

Intestinal Microbiota Transplantation in Patients With Chronic Heart Failure

Recruiting
NCT06567808Phase 4

Prevention of Infections in Cardiac Surgery (PICS): a Cluster-randomized Factorial Cross-over Trial

Not Yet Recruiting
NCT04872400Phase 4

Acute Application of Antibiotic Powder in Open Fracture Wounds

Completed
NCT07435051Phase 3

Prospective, Randomized, Multicenter Clinical Trial of Bisphosphonates Combined With Vancomycin for the Treatment of Cierny-Mader Type I and III Osteomyelitis

Not Yet Recruiting
NCT06582264Phase 1

A Phase 1b Trial to Evaluate the Safety of MB310 in Patients With Active, Mild-to-Moderate Ulcerative Colitis

Completed
NCT06954129Phase 4

A Pragmatic Clinical Trial Comparing the Risk of Acute Kidney Injury During Treatment With Vancomycin and Piperacillin-Tazobactam vs. Vancomycin and Cefepime in Hospitalized Patients

Recruiting
NCT04793152Not Applicable

Vancomycin Dosing for Serious MRSA Infections: A Non-inferiority Randomized Trial of Trough Level Versus AUC/MIC

Recruiting
NCT04666948Phase 4

Precision Dosing of Vancomycin in Critically Ill Children

Completed
NCT06426836Not Applicable

Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO)

Recruiting
NCT03546829Phase 1

Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

Recruiting
NCT05079620Phase 4

Early Antibiotics After Aspiration in ICU Patients

Terminated
NCT04729322Phase 2

Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders

Active Not Recruiting
NCT07282782Phase 4

A Prospective, Randomized Parallel Group Study of the Efficacy of Vancomycin Administered Through Intraarticular Injection Versus Intraosseous Injection Versus Intravenous Infusion in Patients Undergoing Total Knee Arthroplasty

Recruiting
NCT02667418Phase 4

Optimal Treatment for Recurrent Clostridium Difficile

Terminated
NCT04138706Phase 3

Initial Vancomycin Taper for the Prevention of Recurrent Clostridium Difficile Infection

Completed
NCT02284126Phase 3

Topical Vancomycin for Neurosurgery Wound Prophylaxis

Completed
NCT05137119Phase 4

Staphylococcus Aureus Network Adaptive Platform Trial

Recruiting
NCT06540391Phase 1

A Phase 1b Trial to Evaluate Safety of MB097 in Combination With Pembrolizumab in Melanoma Patients

Active Not Recruiting
NCT06716749Phase 2

Effectiveness of Adding Morphine to Intraosseous Vancomycin for Pain Control in Total Knee Arthroplasty

Completed

Drug Details

Intervention Type
DRUG
Total Trials
214