Success Metrics

Clinical Success Rate
44.4%

Based on 4 completed trials

Completion Rate
44%(4/9)
Active Trials
4(31%)
Results Posted
225%(9 trials)
Terminated
5(38%)

Phase Distribution

Ph phase_3
2
15%
Ph phase_1
8
62%
Ph phase_2
3
23%

Phase Distribution

8

Early Stage

3

Mid Stage

2

Late Stage

Phase Distribution13 total trials
Phase 1Safety & dosage
8(61.5%)
Phase 2Efficacy & side effects
3(23.1%)
Phase 3Large-scale testing
2(15.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

44.4%

4 of 9 finished

Non-Completion Rate

55.6%

5 ended early

Currently Active

4

trials recruiting

Total Trials

13

all time

Status Distribution
Active(4)
Completed(4)
Terminated(5)

Detailed Status

Terminated5
Active, not recruiting4
Completed4

Development Timeline

Analytics

Development Status

Total Trials
13
Active
4
Success Rate
44.4%
Most Advanced
Phase 3

Trials by Phase

Phase 18 (61.5%)
Phase 23 (23.1%)
Phase 32 (15.4%)

Trials by Status

active_not_recruiting431%
completed431%
terminated538%

Recent Activity

Clinical Trials (13)

Showing 13 of 13 trials
NCT03217747Phase 1

Avelumab, Utomilumab, Anti-OX40 Antibody PF-04518600, and Radiation Therapy in Treating Patients With Advanced Malignancies

Active Not Recruiting
NCT03971409Phase 2

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

Active Not Recruiting
NCT05059522Phase 3

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

Active Not Recruiting
NCT03290937Phase 1

Utomilumab, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Metastatic Colorectal Cancer

Completed
NCT03414658Phase 2

The AVIATOR Study: Trastuzumab and Vinorelbine With Avelumab OR Avelumab & Utomilumab in Advanced HER2+ Breast Cancer

Active Not Recruiting
NCT03440567Phase 1

Avelumab, Utomilumab, Rituximab, Ibrutinib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Mantle Cell Lymphoma

Completed
NCT03636503Phase 1

Rituximab + Immunotherapy in Follicular Lymphoma

Terminated
NCT03318900Phase 1

T-Cell Infusion, Aldesleukin, and Utomilumab in Treating Patients With Recurrent Ovarian Cancer

Completed
NCT02554812Phase 1

A Study Of Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley)

Terminated
NCT03704298Phase 1

Safety and Efficacy of Axicabtagene Ciloleucel in Combination With Utomilumab in Adults With Refractory Large B-cell Lymphoma

Terminated
NCT03258008Phase 2

Utomilumab and ISA101b Vaccination in Patients With HPV-16-Positive Incurable Oropharyngeal Cancer

Terminated
NCT03364348Phase 1

4-1BB Agonist Monoclonal Antibody PF-05082566 With Trastuzumab Emtansine or Trastuzumab in Treating Patients With Advanced HER2-Positive Breast Cancer

Completed
NCT02951156Phase 3

Avelumab In Combination Regimens That Include An Immune Agonist, Epigenetic Modulator, CD20 Antagonist and/or Conventional Chemotherapy in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (R/R DLBCL)

Terminated

All 13 trials loaded

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
13