Success Metrics

Clinical Success Rate
18.8%

Based on 3 completed trials

Completion Rate
19%(3/16)
Active Trials
3(14%)
Results Posted
467%(14 trials)
Terminated
13(62%)

Phase Distribution

Ph phase_1
6
29%
Ph phase_2
15
71%

Phase Distribution

6

Early Stage

15

Mid Stage

0

Late Stage

Phase Distribution21 total trials
Phase 1Safety & dosage
6(28.6%)
Phase 2Efficacy & side effects
15(71.4%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

16.7%

3 of 18 finished

Non-Completion Rate

83.3%

15 ended early

Currently Active

3

trials recruiting

Total Trials

21

all time

Status Distribution
Active(3)
Completed(3)
Terminated(15)

Detailed Status

Terminated13
Completed3
Active, not recruiting3
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
21
Active
3
Success Rate
18.8%
Most Advanced
Phase 2

Trials by Phase

Phase 16 (28.6%)
Phase 215 (71.4%)

Trials by Status

terminated1362%
withdrawn210%
completed314%
active_not_recruiting314%

Recent Activity

Clinical Trials (21)

Showing 20 of 21 trialsScroll for more
NCT03269669Phase 2

Obinutuzumab With or Without Umbralisib, Lenalidomide, or Combination Chemotherapy in Treating Patients With Relapsed or Refractory Grade I-IIIa Follicular Lymphoma

Active Not Recruiting
NCT03919175Phase 2

Umbralisib and Rituximab as Initial Therapy for Patients With Follicular Lymphoma and Marginal Zone Lymphoma

Terminated
NCT04624633Phase 2

Acalabrutinib, Umbralisib, and Ublituximab (AU2) In Relapsed and Untreated CLL

Active Not Recruiting
NCT04163718Phase 2

TGR-1202 (Umbralisib) in Treatment Naïve Patients With Chronic Lymphocytic Leukemia (CLL)

Terminated
NCT04783415Phase 2

Acalabrutinib, Umbralisib, and Ublituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma

Active Not Recruiting
NCT03671590Phase 1

Study of TG-1701, an Irreversible Bruton's Tyrosine Kinase Inhibitor, in Patients With B-Cell Malignancies

Terminated
NCT02742090Phase 2

Evaluate the Efficacy and Safety of TGR-1202 in Participants With Chronic Lymphocytic Leukemia Who Are Intolerant to Prior Therapy

Terminated
NCT03801525Phase 2

Study to Assess the Efficacy and Safety of Ublituximab in Combination With Umbralisib and Venetoclax Compared to Ublituximab in Combination With Umbralisib in Subjects With CLL (ULTRA-V)

Terminated
NCT04508647Phase 2

Ublituximab Followed by Response-driven Addition of Umbralisib for Treatment-naive Follicular or Marginal Zone Lymphoma

Completed
NCT04692155Phase 1

Clinical Trial of Ublituximab and Umbralisib With CHOP (U2-CHOP) Followed by U2 Maintenance (U2-CHOP-U2) in Previously Untreated Mantle Cell Lymphoma (MCL)

Terminated
NCT03828448Phase 2

Study to Assess Umbralisib Plus Ublituximab in Participants With Treatment Naïve Follicular Lymphoma

Terminated
NCT04016805Phase 2

Study to Assess the Efficacy and Safety of Ublituximab and Umbralisib in Participants With Chronic Lymphocytic Leukemia (CLL) Currently Treated With Ibrutinib, Acalabrutinib or Venetoclax

Terminated
NCT03364231Phase 2

Study to Assess the Efficacy and Safety of Umbralisib in Participants With Non-Follicular Indolent Non-Hodgkin's Lymphoma

Completed
NCT02656303Phase 2

A Study to Evaluate the Safety and Efficacy of Ublituximab in Combination With Umbralisib for Participants Previously Enrolled in Protocol UTX-TGR-304

Terminated
NCT04149821Phase 2

Umbralisib Plus Ublituximab (U2) in Progressive CLL After Novel Therapy

Terminated
NCT05152459Phase 1

Tazemetostat in Combination With Umbralisib and Ublituximab for the Treatment Relapsed or Refractory Follicular Lymphoma

Withdrawn
NCT03776864Phase 2

Umbralisib and Pembrolizumab in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

Terminated
NCT02535286Phase 1

Study of Immunotherapy in Combination With Ublituximab and Umbralisib in Patients With Relapsed-refractory CLL or Richter's Transformation

Completed
NCT04635683Phase 1

Lenalidomide, Umbralisib, and Ublituximab for the Treatment of Relapsed or Refractory Indolent Non-Hodgkin Lymphoma or Mantle Cell Lymphoma

Withdrawn
NCT03379051Phase 1

Phase I/II Study of Venetoclax or Lenalidomide in Combination With Ublituximab and Umbralisib in Subjects With Relapsed or Refractory CLL/SLL and NHL

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
21