Success Metrics

Clinical Success Rate
33.3%

Based on 1 completed trials

Completion Rate
33%(1/3)
Active Trials
9(75%)
Results Posted
400%(4 trials)
Terminated
2(17%)

Phase Distribution

Ph phase_1
4
33%
Ph phase_2
7
58%
Ph early_phase_1
1
8%

Phase Distribution

5

Early Stage

7

Mid Stage

0

Late Stage

Phase Distribution12 total trials
Early Phase 1First-in-human
1(8.3%)
Phase 1Safety & dosage
4(33.3%)
Phase 2Efficacy & side effects
7(58.3%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

33.3%

1 of 3 finished

Non-Completion Rate

66.7%

2 ended early

Currently Active

9

trials recruiting

Total Trials

12

all time

Status Distribution
Active(9)
Completed(1)
Terminated(2)

Detailed Status

Recruiting5
Active, not recruiting4
Terminated2
Completed1

Development Timeline

Analytics

Development Status

Total Trials
12
Active
9
Success Rate
33.3%
Most Advanced
Phase 2

Trials by Phase

Early Phase 11 (8.3%)
Phase 14 (33.3%)
Phase 27 (58.3%)

Trials by Status

completed18%
terminated217%
recruiting542%
active_not_recruiting433%

Recent Activity

Clinical Trials (12)

Showing 12 of 12 trials
NCT05804227Early Phase 1

Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Gliomas

Recruiting
NCT02465060Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Active Not Recruiting
NCT03155620Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Active Not Recruiting
NCT06411821Phase 2

Ulixertinib in People With Histiocytic Neoplasms

Recruiting
NCT03698994Phase 2

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Active Not Recruiting
NCT06400225Phase 2

Testing BVD-523FB (Ulixertinib) as Potentially Targeted Treatment in Cancers With Genetic Changes (MATCH - Subprotocol Z1L)

Active Not Recruiting
NCT05985954Phase 1

Open-label Phase 1b Study of Ulixertinib and Cetuximab or Ulixertinib in Combination With Cetuximab and Encorafenib in Patients With Unresectable or Metastatic Colorectal Cancer Who Have Previously Received EGFR or BRAF-directed Therapy

Recruiting
NCT06773195Phase 1

A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis

Recruiting
NCT05221320Phase 2

Trial of Ulixertinib in Combination With Hydroxychloroquine in Patients With Advanced Gastrointestinal (GI) Malignancies

Terminated
NCT03454035Phase 1

Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors

Recruiting
NCT04145297Phase 1

Ulixertinib (BVD-523) and Hydroxychloroquine in Patients W Advanced MAPK-Mutated Gastrointestinal Adenocarcinomas

Completed
NCT04488003Phase 2

Study of Ulixertinib for Patients With Advanced Malignancies Harboring MEK or Atypical BRAF Alterations

Terminated

All 12 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
12