Success Metrics

Clinical Success Rate
94.1%

Based on 16 completed trials

Completion Rate
94%(16/17)
Active Trials
0(0%)
Results Posted
0%(0 trials)
Terminated
1(6%)

Phase Distribution

Ph phase_1
3
18%
Ph not_applicable
4
24%
Ph phase_2
4
24%
Ph phase_3
6
35%

Phase Distribution

3

Early Stage

4

Mid Stage

6

Late Stage

Phase Distribution17 total trials
Phase 1Safety & dosage
3(17.6%)
Phase 2Efficacy & side effects
4(23.5%)
Phase 3Large-scale testing
6(35.3%)
N/ANon-phased studies
4(23.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

94.1%

16 of 17 finished

Non-Completion Rate

5.9%

1 ended early

Currently Active

0

trials recruiting

Total Trials

17

all time

Status Distribution
Completed(16)
Terminated(1)

Detailed Status

Completed16
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
17
Active
0
Success Rate
94.1%
Most Advanced
Phase 3

Trials by Phase

Phase 13 (17.6%)
Phase 24 (23.5%)
Phase 36 (35.3%)
N/A4 (23.5%)

Trials by Status

completed1694%
terminated16%

Recent Activity

Clinical Trials (17)

Showing 17 of 17 trials
NCT00001013Phase 3

Comparison of Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

Completed
NCT00001014Phase 3

Trimetrexate Plus Leucovorin Calcium Rescue Versus Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS

Completed
NCT00000998Phase 1

A Study of Trimetrexate in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Not Previously Treated for PCP

Completed
NCT00000730Phase 3

Comparison of Three Treatments for Pneumocystis Pneumonia in AIDS Patients

Terminated
NCT00000714Phase 3

An Open, Prospective, Multicenter Study of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia (PCP) and Serious Intolerance to Approved Therapies

Completed
NCT00002955Phase 2

Combination Chemotherapy in Treating Patients With Advanced Cancer of the Pancreas

Completed
NCT00003446Phase 2

Chemotherapy in Treating Patients With Recurrent or Metastatic Colorectal Cancer

Completed
NCT00003776Phase 2

Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma

Completed
NCT00002738Phase 2

Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia, Osteosarcoma, or Non-Hodgkin's Lymphoma

Completed
NCT00119301Phase 1

Methotrexate, Trimetrexate Glucuronate, and Leucovorin in Treating Patients With Refractory or Recurrent Osteosarcoma

Completed
NCT00000724Phase 3

A Study of Trimetrexate With Leucovorin Rescue for AIDS Patients Who Are Refractory to Standard Therapies for Pneumocystis Carinii Pneumonia

Completed
NCT00001016Phase 3

A Treatment Protocol for the Use of Trimetrexate With Leucovorin Rescue for AIDS Patients With Pneumocystis Carinii Pneumonia and Serious Intolerance to Approved Therapies

Completed
NCT00002103Not Applicable

A Compassionate Treatment Protocol for the Use of Trimetrexate Glucuronate (Neutrexin) With Leucovorin Protection for European Adult Patients (>= 13 Years Old) With Pneumocystis Carinii Pneumonia

Completed
NCT00002434Not Applicable

A Study of Neutrexin Plus Leucovorin in the Treatment of Pneumocystis Carinii Pneumonia (PCP)

Completed
NCT00002102Not Applicable

A Compassionate Treatment Protocol for the Use of Trimetrexate Glucuronate With Leucovorin Protection for Patients With Pneumocystis Carinii Pneumonia.

Completed
NCT00002317Not Applicable

A Study of Trimetrexate Plus Leucovorin in Children With Pneumocystis Carinii Pneumonia

Completed
NCT00002120Phase 1

Randomized Phase I Study of Trimetrexate Glucuronate (TMTX) With Leucovorin (LCV) Protection Plus Dapsone Versus Trimethoprim / Sulfamethoxazole (TMP/SMX) for Treatment of Moderately Severe Episodes of Pneumocystis Carinii Pneumonia

Completed

All 17 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
17