Success Metrics

Clinical Success Rate
54.5%

Based on 6 completed trials

Completion Rate
55%(6/11)
Active Trials
8(31%)
Results Posted
150%(9 trials)
Terminated
5(19%)

Phase Distribution

Ph phase_4
2
8%
Ph phase_1
2
8%
Ph phase_2
18
69%
Ph phase_3
3
12%

Phase Distribution

2

Early Stage

18

Mid Stage

5

Late Stage

Phase Distribution25 total trials
Phase 1Safety & dosage
2(8.0%)
Phase 2Efficacy & side effects
18(72.0%)
Phase 3Large-scale testing
3(12.0%)
Phase 4Post-market surveillance
2(8.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

54.5%

6 of 11 finished

Non-Completion Rate

45.5%

5 ended early

Currently Active

8

trials recruiting

Total Trials

26

all time

Status Distribution
Active(12)
Completed(6)
Terminated(5)
Other(3)

Detailed Status

Recruiting7
Completed6
Terminated5
unknown3
Not yet recruiting3
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
26
Active
8
Success Rate
54.5%
Most Advanced
Phase 4

Trials by Phase

Phase 12 (8.0%)
Phase 218 (72.0%)
Phase 33 (12.0%)
Phase 42 (8.0%)

Trials by Status

recruiting727%
active_not_recruiting14%
completed623%
terminated519%
unknown312%
enrolling_by_invitation14%
not_yet_recruiting312%

Recent Activity

Clinical Trials (26)

Showing 20 of 26 trialsScroll for more
NCT06027268Phase 2

Phase II Trial of Trilaciclib, Pembrolizumab, Gemcitabine and Carboplatin in Metastatic Triple-Negative Breast Cancer

Active Not Recruiting
NCT05578326Phase 2

Study of Trilaciclib and Lurbinectidin

Recruiting
NCT07473128Phase 3

Effect of Trilaciclib in the Prevention of Myelosupression in Subjects With Limited-stage Small Cell Lung Cancer

Not Yet Recruiting
NCT06370416Phase 2

the Prevention of Bone Marrow Suppression Caused by Chemotherapy in Advanced NSCLC With Trilaciclib

Enrolling By Invitation
NCT07255612Phase 2

Bone Marrow Protection, Safety, Efficacy of Trilaciclib and Eribulin in Locally Advanced or Metastatic TNBC(Triple-negative Breast Cancer)

Not Yet Recruiting
NCT03041311Phase 2

Carboplatin, Etoposide, and Atezolizumab With or Without Trilaciclib (G1T28), a CDK4/6 Inhibitor, in Extensive-Stage SCLC

Completed
NCT02514447Phase 1

Trilaciclib (G1T28) in Patients With Previously Treated Extensive Stage SCLC Receiving Topotecan Chemotherapy

Completed
NCT04887831Phase 2

Trilaciclib, a CDK 4/6 Inhibitor, in Patients With Advanced/Metastatic Bladder Cancer Receiving Chemotherapy Then Avelumab

Terminated
NCT05874401Phase 4

Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving Topotecan

Recruiting
NCT06955156Phase 2

Trilaciclib Combined With Anti-PD-1 Antibody and Chemotherapy in the Treatment of Locally Advanced TNBC

Recruiting
NCT05113966Phase 2

Trilaciclib in Patients Receiving Sacituzumab Govitecan-hziy for Triple Negative Breast Cancer

Terminated
NCT06714266Phase 2

Trilaciclib in Preventing Hematopoietic Suppression in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Not Yet Recruiting
NCT06714383Phase 2

Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma

Recruiting
NCT04607668Phase 3

Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving FOLFOXIRI/Bevacizumab for Metastatic Colorectal Cancer (mCRC):

Terminated
NCT06698965Phase 2

Efficacy and Safety of First-line Treatment for Extensive-stage Small Cell Lung Cancer Using a Combination Therapy of Trilaciclib, Envafolimab, Etoposide, and Carboplatin

Recruiting
NCT06490081Phase 2

Trilaciclib Prevents Myelosuppression With Chemoradiotherapy

Recruiting
NCT04799249Phase 3

Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving Gemcitabine and Carboplatin for Metastatic Triple-Negative Breast Cancer (TNBC)

Completed
NCT05112536Phase 2

Trilaciclib, a CDK4/6 Inhibitor, in Patients With Early-Stage Triple Negative Breast Cancer

Completed
NCT06217003Phase 2

Trilaciclib Combined With Chemotherapy for Perioperative Treatment of Osteosarcoma

Unknown
NCT05978648Phase 2

Trilaciclib in Patients With Early-Stage HR-negative Breast Cancer Receiving Adjuvant Chemotherapy

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
26