Success Metrics

Clinical Success Rate
100.0%

Based on 17 completed trials

Completion Rate
100%(17/17)
Active Trials
8(25%)
Results Posted
29%(5 trials)

Phase Distribution

Ph phase_3
3
9%
Ph phase_1
3
9%
Ph phase_2
25
78%

Phase Distribution

3

Early Stage

25

Mid Stage

3

Late Stage

Phase Distribution31 total trials
Phase 1Safety & dosage
3(9.7%)
Phase 2Efficacy & side effects
25(80.6%)
Phase 3Large-scale testing
3(9.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

17 of 17 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

8

trials recruiting

Total Trials

32

all time

Status Distribution
Active(8)
Completed(17)
Other(7)

Detailed Status

Completed17
unknown7
Recruiting7
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
32
Active
8
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 13 (9.7%)
Phase 225 (80.6%)
Phase 33 (9.7%)

Trials by Status

unknown722%
recruiting722%
completed1753%
active_not_recruiting13%

Recent Activity

Clinical Trials (32)

Showing 20 of 32 trialsScroll for more
NCT07493538Phase 2

MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases

Recruiting
NCT03980769Phase 2

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Thiotepa in Treating Patients With Non-malignant Disorders

Recruiting
NCT04965597Phase 2

Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

Completed
NCT04195633Phase 2

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

Recruiting
NCT04994808Phase 2

Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid Leukemia

Active Not Recruiting
NCT02349906Phase 2

Treosulfan-based Versus Busulfan-based Conditioning in Paediatric Patients With Non-malignant Diseases

Completed
NCT05534620Phase 1

Effect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics

Recruiting
NCT05636787Phase 2

Clinical Trial Investigating the Chemotherapeutic Compound Treosulfan (Trecondi® Ideogen) in Myeloma Patients

Recruiting
NCT01949129Phase 2

Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia

Recruiting
NCT06198842Phase 2

Low Dose Treosulfan Based Conditioning Regimen and PTCy in HSCT for Nijmegen Breakage Syndrome

Recruiting
NCT03961919Phase 2

Phase II Trial in Elderly Patients With AML or MDS in Complete Remission Not Eligible for Allogenic Transplant

Completed
NCT01063647Phase 1

Dose-range Finding Treosulfan-based Conditioning

Completed
NCT00796068Phase 2

Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematological Cancer Who Are Undergoing Umbilical Cord Blood Transplant

Completed
NCT00919503Phase 2

Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders

Completed
NCT00860574Phase 2

Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia

Completed
NCT01894477Phase 2

Treo/Flu/TBI With Donor Stem Cell Transplant for Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia

Unknown
NCT00822393Phase 3

Clinical Phase III Trial Treosulfan-based Conditioning Versus Reduced-intensity Conditioning (RIC)

Completed
NCT04400045Phase 2

Low Dose Treosulfan Based Conditioning Regimen in HSCT for Nijmegen Breakage Syndrome

Unknown
NCT02333058Phase 2

Treosulfan-based Conditioning in Paediatric Patients With Haematological Malignancies

Completed
NCT00987636Phase 3

Study in Localized and Disseminated Ewing Sarcoma

Completed

Drug Details

Intervention Type
DRUG
Total Trials
32