Success Metrics

Clinical Success Rate
45.5%

Based on 5 completed trials

Completion Rate
45%(5/11)
Active Trials
2(14%)
Results Posted
160%(8 trials)
Terminated
6(43%)

Phase Distribution

Ph phase_2
6
43%
Ph not_applicable
3
21%
Ph early_phase_1
1
7%
Ph phase_4
4
29%

Phase Distribution

1

Early Stage

6

Mid Stage

4

Late Stage

Phase Distribution14 total trials
Early Phase 1First-in-human
1(7.1%)
Phase 2Efficacy & side effects
6(42.9%)
Phase 4Post-market surveillance
4(28.6%)
N/ANon-phased studies
3(21.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

45.5%

5 of 11 finished

Non-Completion Rate

54.5%

6 ended early

Currently Active

2

trials recruiting

Total Trials

14

all time

Status Distribution
Active(3)
Completed(5)
Terminated(6)

Detailed Status

Terminated6
Completed5
Recruiting2
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
14
Active
2
Success Rate
45.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (7.1%)
Phase 26 (42.9%)
Phase 44 (28.6%)
N/A3 (21.4%)

Trials by Status

terminated643%
completed536%
not_yet_recruiting17%
recruiting214%

Recent Activity

2 active trials
Showing 5 of 14
recruitingphase_4

Examining the Effects of Estradiol on Neural and Molecular Response to Reward

NCT05282277
not_yet_recruitingnot_applicable

Comparison of Oral Dydrogesterone and Vaginal Progesterone in Menopausal Hormone Therapy

NCT07496294
terminatedphase_2

Neurocognitive Mechanisms of Perimenstrual Estrogen Effects on Suicidality

NCT06191289
recruitingphase_4

Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression

NCT06610305
terminatedphase_2

Phase II Trial of Transdermal Estradiol for Hormone Refractory Prostate Cancer

NCT00176644
View all 14 trials

Clinical Trials (14)

Showing 14 of 14 trials
NCT05282277Phase 4

Examining the Effects of Estradiol on Neural and Molecular Response to Reward

Recruiting
NCT07496294Not Applicable

Comparison of Oral Dydrogesterone and Vaginal Progesterone in Menopausal Hormone Therapy

Not Yet Recruiting
NCT06191289Phase 2

Neurocognitive Mechanisms of Perimenstrual Estrogen Effects on Suicidality

Terminated
NCT06610305Phase 4

Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression

Recruiting
NCT00176644Phase 2

Phase II Trial of Transdermal Estradiol for Hormone Refractory Prostate Cancer

Terminated
NCT00744328Phase 4

Postpartum Depression: Transdermal Estradiol Versus Sertraline

Terminated
NCT02486757Early Phase 1

Investigation of Female Reproductive Hormone Dynamics During Adolescence

Completed
NCT01928082Phase 2

The Effects of Estrogen Replacement Therapy in Postmenopausal Women With Hypercalciuria and Low Bone Mass

Terminated
NCT00066157Phase 2

Alzheimer's Disease: Therapeutic Potential of Estrogen

Completed
NCT00789802Not Applicable

A Randomized Controlled Trial of Oral Naproxen and Transdermal Estradiol for Bleeding in LNG-IUC

Completed
NCT01633814Not Applicable

Hormone Replacement and Neural Cardiovascular Control in Postmenopausal Women

Terminated
NCT00459810Phase 2

Paclitaxel Poliglumex and Estradiol in Treating Patients With Stage IV Prostate Cancer

Terminated
NCT00030147Phase 4

Raloxifene and Rimostil for Perimenopause-Related Depression

Completed
NCT00167648Phase 2

Neoadjuvant Estradiol or Androgen Deprivation in Clinically Localized Prostate Cancer

Completed

All 14 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
14