Success Metrics

Clinical Success Rate
81.5%

Based on 88 completed trials

Completion Rate
81%(88/108)
Active Trials
31(20%)
Results Posted
90%(79 trials)
Terminated
20(13%)

Phase Distribution

Ph phase_2
91
59%
Ph early_phase_1
3
2%
Ph phase_3
4
3%
Ph not_applicable
10
6%
Ph phase_1
44
28%

Phase Distribution

47

Early Stage

91

Mid Stage

4

Late Stage

Phase Distribution152 total trials
Early Phase 1First-in-human
3(2.0%)
Phase 1Safety & dosage
44(28.9%)
Phase 2Efficacy & side effects
91(59.9%)
Phase 3Large-scale testing
4(2.6%)
N/ANon-phased studies
10(6.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

75.9%

88 of 116 finished

Non-Completion Rate

24.1%

28 ended early

Currently Active

31

trials recruiting

Total Trials

155

all time

Status Distribution
Active(33)
Completed(88)
Terminated(28)
Other(6)

Detailed Status

Completed88
Terminated20
Recruiting18
Active, not recruiting13
Withdrawn8
unknown6

Development Timeline

Analytics

Development Status

Total Trials
155
Active
31
Success Rate
81.5%
Most Advanced
Phase 3

Trials by Phase

Early Phase 13 (2.0%)
Phase 144 (28.9%)
Phase 291 (59.9%)
Phase 34 (2.6%)
N/A10 (6.6%)

Trials by Status

completed8857%
terminated2013%
active_not_recruiting138%
withdrawn85%
unknown64%
recruiting1812%
not_yet_recruiting21%

Recent Activity

Clinical Trials (155)

Showing 20 of 155 trialsScroll for more
NCT05564390Phase 2

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

Recruiting
NCT02727803Phase 2

Personalized NK Cell Therapy in CBT

Recruiting
NCT03670966Phase 1

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

Recruiting
NCT01231412Phase 3

Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

Completed
NCT07225985Phase 1

Pralatrexate With Bendamustine and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma

Recruiting
NCT03192397Phase 1

Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

Active Not Recruiting
NCT04384692Phase 2

Peritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis

Active Not Recruiting
NCT00792948Phase 2

Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT06954987Phase 2

Venetoclax or Placebo in Combination With Reduced-Intensity Conditioning Hematopoietic Cell (Bone Marrow/Blood Stem Cell) Transplant and as Maintenance Therapy After Transplant in Patients With Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Not Yet Recruiting
NCT02251821Phase 2

JAK Inhibitor Before Donor Stem Cell Transplant in Treating Patients With Primary or Secondary Myelofibrosis

Completed
NCT04380831Early Phase 1

TBI Using IMRT and Cyclophosphamide Prior to Stem Cell Transplant for the Treatment of Severe Systemic Sclerosis

Recruiting
NCT04904588Phase 2

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Active Not Recruiting
NCT04579523Phase 1

²¹¹At-OKT10-B10 and Fludarabine Alone or in Combination With Cyclophosphamide and Low-Dose TBI Before Donor Stem Cell Transplant for the Treatment of Newly Diagnosed, Recurrent, or Refractory High-Risk Multiple Myeloma

Not Yet Recruiting
NCT03970096Phase 2

Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)

Recruiting
NCT06752694Phase 2

Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic Anemia

Recruiting
NCT04375631Phase 1

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Recruiting
NCT04195633Phase 2

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

Recruiting
NCT06001385Phase 2

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis

Active Not Recruiting
NCT07046078Phase 2

Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer

Recruiting
NCT03032783Phase 2

A Two Step Approach to Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Hematologic Malignancies-Increasing GVT Effects Without Increasing Toxicity

Completed

Drug Details

Intervention Type
RADIATION
Total Trials
155