Success Metrics

Clinical Success Rate
64.9%

Based on 48 completed trials

Completion Rate
65%(48/74)
Active Trials
31(26%)
Results Posted
123%(59 trials)
Terminated
26(21%)

Phase Distribution

Ph early_phase_1
2
2%
Ph phase_1
35
29%
Ph phase_2
65
54%
Ph phase_3
7
6%
Ph not_applicable
10
8%

Phase Distribution

37

Early Stage

65

Mid Stage

7

Late Stage

Phase Distribution119 total trials
Early Phase 1First-in-human
2(1.7%)
Phase 1Safety & dosage
35(29.4%)
Phase 2Efficacy & side effects
65(54.6%)
Phase 3Large-scale testing
7(5.9%)
N/ANon-phased studies
10(8.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

60.8%

48 of 79 finished

Non-Completion Rate

39.2%

31 ended early

Currently Active

31

trials recruiting

Total Trials

121

all time

Status Distribution
Active(34)
Completed(48)
Terminated(31)
Other(8)

Detailed Status

Completed48
Terminated26
Recruiting24
unknown8
Active, not recruiting7
Withdrawn5

Development Timeline

Analytics

Development Status

Total Trials
121
Active
31
Success Rate
64.9%
Most Advanced
Phase 3

Trials by Phase

Early Phase 12 (1.7%)
Phase 135 (29.4%)
Phase 265 (54.6%)
Phase 37 (5.9%)
N/A10 (8.4%)

Trials by Status

active_not_recruiting76%
terminated2621%
recruiting2420%
completed4840%
withdrawn54%
unknown87%
not_yet_recruiting32%

Recent Activity

Clinical Trials (121)

Showing 20 of 121 trialsScroll for more
NCT07524530Phase 2

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

Not Yet Recruiting
NCT07566377Phase 2

Cord Blood Transplantation in Children and Young Adults With Blood Cancer

Recruiting
NCT05463133Phase 1

Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists

Recruiting
NCT04339777Phase 2

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

Recruiting
NCT03214354Phase 2

Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor

Recruiting
NCT03910452Early Phase 1

Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide

Active Not Recruiting
NCT03263559Phase 2

Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)

Completed
NCT07162038Phase 1

Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation

Recruiting
NCT02629120Phase 1

High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous Disease

Active Not Recruiting
NCT02828592Phase 2

Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia

Recruiting
NCT07493538Phase 2

MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases

Recruiting
NCT01962636Not Applicable

Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

Recruiting
NCT06872333Phase 2

Allo HSCT for High Risk Hemoglobinopathies

Recruiting
NCT06623630Phase 1

Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function

Recruiting
NCT06078696Phase 1

Siplizumab for Sickle Cell Disease Transplant

Terminated
NCT05170828Phase 1

Cryopreserved MMUD BM With PTCy for Hematologic Malignancies

Withdrawn
NCT01203722Phase 1

Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies

Completed
NCT03480360Phase 3

Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' Expression

Active Not Recruiting
NCT06028828Phase 2

Risk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation

Recruiting
NCT03159702Phase 2

Propylene Glycol-Free Melphalan HCl (EVOMELA®) in Combination With Fludarabine and Total Body Irradiation Based Reduced Intensity Conditioning for Haploidentical Transplantation

Completed

Drug Details

Intervention Type
RADIATION
Total Trials
121