Success Metrics

Clinical Success Rate
81.6%

Based on 160 completed trials

Completion Rate
82%(160/196)
Active Trials
84(25%)
Results Posted
66%(105 trials)
Terminated
36(11%)

Phase Distribution

Ph phase_2
82
24%
Ph not_applicable
18
5%
Ph phase_1
94
28%
Ph early_phase_1
2
1%
Ph phase_3
67
20%
Ph phase_4
36
11%

Phase Distribution

96

Early Stage

82

Mid Stage

103

Late Stage

Phase Distribution299 total trials
Early Phase 1First-in-human
2(0.7%)
Phase 1Safety & dosage
94(31.4%)
Phase 2Efficacy & side effects
82(27.4%)
Phase 3Large-scale testing
67(22.4%)
Phase 4Post-market surveillance
36(12.0%)
N/ANon-phased studies
18(6.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

77.7%

160 of 206 finished

Non-Completion Rate

22.3%

46 ended early

Currently Active

84

trials recruiting

Total Trials

336

all time

Status Distribution
Active(100)
Completed(160)
Terminated(46)
Other(30)

Detailed Status

Completed160
Recruiting50
Terminated36
Active, not recruiting34
unknown28
Not yet recruiting15

Development Timeline

Analytics

Development Status

Total Trials
336
Active
84
Success Rate
81.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (0.7%)
Phase 194 (31.4%)
Phase 282 (27.4%)
Phase 367 (22.4%)
Phase 436 (12.0%)
N/A18 (6.0%)

Trials by Status

enrolling_by_invitation10%
recruiting5015%
unknown288%
completed16048%
suspended21%
terminated3611%
not_yet_recruiting154%
active_not_recruiting3410%
withdrawn103%

Recent Activity

Clinical Trials (336)

Showing 20 of 336 trialsScroll for more
NCT03533283Phase 1

An Open-Label Phase lB/II Study of Glofitamab and Atezolizumab or Polatuzumab Vedotin in Adult Patients With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

Active Not Recruiting
NCT04408638Phase 3

A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Active Not Recruiting
NCT05835986Phase 1

A First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7507062 in Participants With Systemic Lupus Erythematosus

Active Not Recruiting
NCT07589634Phase 2

A Study Evaluating the Prophylactic Use of Tocilizumab to Prevent Cytokine Release Syndrome With Ramantamig Administration in Participants With Relapsed/Refractory Multiple Myeloma

Recruiting
NCT07709000Phase 2

A Clinical Trial of MK-1045 in People With B-cell Cancer (MK-1045-006)

Not Yet Recruiting
NCT04980222Phase 2

A Study to Evaluate the Safety and Efficacy of Glofitamab in Combination With Rituximab (R) Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Circulating Tumor (ct)DNA High-Risk Patients With Untreated Diffuse Large B-Cell Lymphoma

Active Not Recruiting
NCT03644667Phase 2

Tocilizumab in Cardiac Transplantation

Completed
NCT03564340Phase 1

Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

Recruiting
NCT06654882Phase 3

Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis

Recruiting
NCT07570173Phase 2

A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)

Recruiting
NCT07609940Phase 4

Adult Outpatient Linvoseltamab With Tocilizumab Prophylaxis to Mitigate the Risk of Cytokine Release Syndrome (CRS)

Recruiting
NCT04066114Phase 1

Treg Modulation With CD28 and IL-6 Receptor Antagonists

Completed
NCT07838974Phase 1

Adding Anakinra and Tocilizumab to Nivolumab and Ipilimumab for the Treatment of Melanoma Patients 50 Years of Age or Older

Not Yet Recruiting
NCT04729959Phase 2

Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent Glioblastoma

Active Not Recruiting
NCT07263776Phase 3

Efficacy and Safety of Interleukin-6 Receptor Inhibitor Combined With Endovascular Treatment in Patients With Acute Anterior Circulation Large Vessel Occlusion Stroke -2

Active Not Recruiting
NCT07335562Phase 3

A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis

Not Yet Recruiting
NCT04910568Phase 1

A Study Evaluating the Safety, Pharmacokinetics, and Activity of Cevostamab in Participants With Relapsed or Refractory Multiple Myeloma

Recruiting
NCT07825064Phase 2

Cevostamab in Combination With Pomalidomide and Dexamethasone After BCMA- Targeting CAR T-Cell Therapy in Participants With Previously Treated Multiple Myeloma

Recruiting
NCT04940299Phase 2

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Active Not Recruiting
NCT05609630Phase 3

Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
336