Success Metrics

Clinical Success Rate
77.8%

Based on 7 completed trials

Completion Rate
78%(7/9)
Active Trials
2(13%)
Results Posted
57%(4 trials)
Terminated
2(13%)

Phase Distribution

Ph phase_1
4
27%
Ph phase_3
1
7%
Ph phase_2
9
60%
Ph early_phase_1
1
7%

Phase Distribution

5

Early Stage

9

Mid Stage

1

Late Stage

Phase Distribution15 total trials
Early Phase 1First-in-human
1(6.7%)
Phase 1Safety & dosage
4(26.7%)
Phase 2Efficacy & side effects
9(60.0%)
Phase 3Large-scale testing
1(6.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

70.0%

7 of 10 finished

Non-Completion Rate

30.0%

3 ended early

Currently Active

2

trials recruiting

Total Trials

15

all time

Status Distribution
Active(2)
Completed(7)
Terminated(3)
Other(3)

Detailed Status

Completed7
unknown3
Terminated2
Withdrawn1
Active, not recruiting1
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
15
Active
2
Success Rate
77.8%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (6.7%)
Phase 14 (26.7%)
Phase 29 (60.0%)
Phase 31 (6.7%)

Trials by Status

withdrawn17%
active_not_recruiting17%
recruiting17%
terminated213%
unknown320%
completed747%

Recent Activity

Clinical Trials (15)

Showing 15 of 15 trials
NCT04817254Phase 2

Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Completed
NCT06816927Phase 2

Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab

Recruiting
NCT04250922Phase 2

LAM561 With RT and TMZ for Adults With Glioblastoma

Active Not Recruiting
NCT03879811Phase 2

Determining the Effects of Temozolomide Followed by Nivolumab in Patients With Colorectal Cancer

Withdrawn
NCT03150862Phase 1

A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma

Completed
NCT03190967Phase 1

T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery

Terminated
NCT03867123Phase 1

A Study to Evaluate the Safety of LAM561 Added to Standard of Care in Newly-diagnosed Glioblastoma Patients

Completed
NCT05589961Early Phase 1

Safety and Efficacy of TRPP Therapy in Glioblastoma Multiforme

Unknown
NCT02903069Phase 1

Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer

Completed
NCT00727506Phase 2

BIBW 2992 (Afatinib) With or Without Daily Temozolomide in the Treatment of Patients With Recurrent Malignant Glioma

Completed
NCT01708174Phase 2

A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB)

Completed
NCT01605162Phase 2

Phase 2 Study of the Poly(ADP-Ribose) Polymerase Inhibitor E7016 in Combination With Temozolomide in Subjects With Wild Type BRAF Stage IV or Unresectable Stage III Melanoma

Terminated
NCT02832635Phase 2

A Clinical Trial on Whole-brain Radiotherapy With Temozolomide Concurrent Chemotherapy or Avoidance of Hippocampus for Patients of Brain Metastases

Unknown
NCT01364064Phase 3

Conventional Adjuvant Temozolomide With Dose Intensive Temozolomide in Patients With Newly Diagnosed Glioblastoma

Completed
NCT01670890Phase 2

Efficacy and Safety of TMZ Plus CDDP in the Patients With Recurrent Malignant Gliomas

Unknown

All 15 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
15