Success Metrics

Clinical Success Rate
100.0%

Based on 39 completed trials

Completion Rate
100%(39/39)
Active Trials
0(0%)
Results Posted
41%(16 trials)

Phase Distribution

Ph phase_1
19
49%
Ph phase_3
13
33%
Ph phase_2
7
18%

Phase Distribution

19

Early Stage

7

Mid Stage

13

Late Stage

Phase Distribution39 total trials
Phase 1Safety & dosage
19(48.7%)
Phase 2Efficacy & side effects
7(17.9%)
Phase 3Large-scale testing
13(33.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

39 of 39 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

0

trials recruiting

Total Trials

39

all time

Status Distribution
Completed(39)

Detailed Status

Completed39

Development Timeline

Analytics

Development Status

Total Trials
39
Active
0
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 119 (48.7%)
Phase 27 (17.9%)
Phase 313 (33.3%)

Trials by Status

completed39100%

Recent Activity

Clinical Trials (39)

Showing 20 of 39 trialsScroll for more
NCT01567735Phase 3

A Study to Evaluate the Efficacy, Safety and Tolerability of TMC435 in Combination With PegIFN Alfa-2a (Pegasys) and Ribavirin (Copegus) in Treatment-Naïve or Treatment-Experienced, Chronic Hepatitis C Virus Genotype-4 Infected Patients

Completed
NCT01846832Phase 3

A Study of TMC435 Plus Pegylated Interferon Alfa-2a and Ribavirin in Participants With Chronic HCV Infection

Completed
NCT01485991Phase 3

TMC435HPC3001 - An Efficacy, Safety and Tolerability Study for TMC435 vs Telaprevir in Combination With PegINFα-2a and Ribavirin in Chronic Hepatitis C Patients Who Were Null or Partial Responders to Prior PegINFα-2a and Ribavirin Therapy

Completed
NCT01323244Phase 3

A Study of TMC435 in Combination With Peginterferon Alfa-2A and Ribavirin for Hepatitis C Virus Genotype-1 Infected Patients Who Participated in a Control Group of a TMC435 Study

Completed
NCT01724086Phase 2

A Study to Evaluate the Safety, Tolerability, and Effectiveness of a 12-Week Combination Therapy of TMC647055 and TMC435 With and Without GSK23336805 With a Pharmacokinetic Enhancer With and Without Ribavirin in Patients Infected With Chronic Genotype 1 Hepatitis C Virus

Completed
NCT01725529Phase 3

An Efficacy, Pharmacokinetics, Safety and Tolerability Study of TMC435 as Part of a Treatment Regimen for Hepatitis C-Infected Patients

Completed
NCT01466790Phase 2

A Study of TMC435 in Combination With PSI-7977 (GS7977) in Chronic Hepatitis C Genotype 1-Infected Prior Null Responders To Peginterferon/Ribavirin Therapy or HCV Treatment-Naive Patients

Completed
NCT01479868Phase 3

A Study to Assess the Safety, Tolerability and Efficacy of TMC435 Along With Pegylated Interferon Alpha-2a (Pegasys) and Ribavirin (Copegus) Triple Therapy in Chronic Hepatitis C Genotype-1 Infected Patients Co-infected With Human Immunodeficiency Virus-Type 1

Completed
NCT00812331Phase 2

A Study to Assess the Anti-viral Activity, Safety, Tolerability and Pharmacokinetics of TMC435350 in Participants Infected With Hepatitis C-Virus (HCV)

Completed
NCT00882908Phase 2

A Study of TMC435 in Combination With Pegylated Interferon Alp\Fa-2a and Ribavirin in Patients Infected With Genotype 1 Hepatitis C Virus Who Never Received Treatment

Completed
NCT01290679Phase 3

An Efficacy, Safety, and Tolerability Study of TMC435 in Treatment-naive, Genotype 1 Hepatitis C-infected Participants

Completed
NCT00980330Phase 2

A Safety and Effectiveness Study of TMC435 in Chronic, Genotype 1, Hepatitis C Patients Who Failed to Previous Standard Treatment

Completed
NCT01289782Phase 3

An Efficacy, Safety, and Tolerability Study of TMC435 in Treatment-naive, Genotype 1 Hepatitis C-infected Patients

Completed
NCT00561353Phase 2

A Study of TMC435350 Administered With or Without Standard of Care Therapy in Participants With Genotype 1 Hepatitis C Virus Infection

Completed
NCT02064842Phase 1

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of TMC647055 in Combination With Ritonavir (Part 1) and the Co-administration of TMC435, TMC647055 and Ritonavir (Part 2) in Healthy Japanese Participants

Completed
NCT01224197Phase 1

TMC435 HPC1004 - Phase I Study Investigating the Pharmacokinetics of TMC435 in Healthy Chinese Volunteers

Completed
NCT01366638Phase 3

A Study of TMC435 in Participants With Genotype 1 Hepatitis C Virus (HCV) Infection

Completed
NCT01281839Phase 3

An Efficacy, Safety and Tolerability Study of TMC435 in Genotype 1 Hepatitis C-infected Patients Who Relapsed After Previous Therapy

Completed
NCT00996476Phase 2

A Study to Assess the Effectiveness, Safety, and Pharmacokinetics of TMC435 in Combination With Peginterferon Alfa-2a and Ribavirin in Hepatitis-C Infected Patients

Completed
NCT01290731Phase 3

A Study of TMC435 in Genotype 1, Hepatitis C-infected Patients Who Relapsed After Previous Interferon (IFN)-Based Therapy

Completed

Drug Details

Intervention Type
DRUG
Total Trials
39