Success Metrics

Clinical Success Rate
100.0%

Based on 11 completed trials

Completion Rate
100%(11/11)
Active Trials
0(0%)
Results Posted
36%(4 trials)

Phase Distribution

Ph phase_2
5
42%
Ph phase_1
6
50%

Phase Distribution

6

Early Stage

5

Mid Stage

0

Late Stage

Phase Distribution11 total trials
Phase 1Safety & dosage
6(54.5%)
Phase 2Efficacy & side effects
5(45.5%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

100.0%

11 of 11 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

0

trials recruiting

Total Trials

12

all time

Status Distribution
Completed(11)
Other(1)

Detailed Status

Completed11
unknown1

Development Timeline

Analytics

Development Status

Total Trials
12
Active
0
Success Rate
100.0%
Most Advanced
Phase 2

Trials by Phase

Phase 16 (54.5%)
Phase 25 (45.5%)

Trials by Status

unknown18%
completed1192%

Recent Activity

Clinical Trials (12)

Showing 12 of 12 trials
NCT00992069Phase 1

Safety, Tolerability, and Effect of TMC207 and Efavirenz in Healthy Volunteers

Completed
NCT02216331Phase 1

PK Interaction Between Rifapentine or Rifampicin and a Single Dose of TMC207 in Healthy Subjects (TMC207-CL002)

Completed
NCT01464762

Early Access of TMC207 in Patients With Extensively Drug Resistant or Pre-XDR Pulmonary Tuberculosis

Unknown
NCT01215110Phase 2

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (TMC207-CL001)

Completed
NCT01341184Phase 1

TMC207 +/- Rifabutin/Rifampin

Completed
NCT01215851Phase 2

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001)

Completed
NCT00910871Phase 2

To Evaluate the Safety, Tolerability, and Efficacy of TMC207 as Part of an Individualized Multi-drug Resistant Tuberculosis (MDR-TB) Treatment Regimen in Participants With Sputum Smear-positive Pulmonary MDR-TB.

Completed
NCT00449644Phase 2

TMC207-TiDP13-C208: Anti-bacterial Activity, Safety, and Tolerability of TMC207 in Participants With Multi-drug Resistant Mycobacterium Tuberculosis (MDR-TB).

Completed
NCT01012284Phase 1

A Study of TMC207 in Patients With Moderately Impaired Hepatic Function

Completed
NCT01291563Phase 1

TMC207TBC1003 - A Study in Healthy Volunteers Investigating the Effect of Single-dose TMC207 on the QT/QTc Interval Under Fed Conditions

Completed
NCT00523926Phase 2

TMC207-C202: Study to Evaluate Bactericidal Activity of Multiple Oral Doses of TMC207 in Subjects With Sputum-Smear Positive Tuberculosis

Completed
NCT00828529Phase 1

TMC207-TiDP13-C110: Interaction Study With Lopinavir/Ritonavir in Healthy Volunteer

Completed

All 12 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
12