Success Metrics

Clinical Success Rate
66.7%

Based on 12 completed trials

Completion Rate
67%(12/18)
Active Trials
4(15%)
Results Posted
100%(12 trials)
Terminated
6(22%)

Phase Distribution

Ph phase_1
10
37%
Ph phase_2
12
44%
Ph not_applicable
2
7%
Ph phase_3
3
11%

Phase Distribution

10

Early Stage

12

Mid Stage

3

Late Stage

Phase Distribution27 total trials
Phase 1Safety & dosage
10(37.0%)
Phase 2Efficacy & side effects
12(44.4%)
Phase 3Large-scale testing
3(11.1%)
N/ANon-phased studies
2(7.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

57.1%

12 of 21 finished

Non-Completion Rate

42.9%

9 ended early

Currently Active

4

trials recruiting

Total Trials

27

all time

Status Distribution
Active(5)
Completed(12)
Terminated(9)
Other(1)

Detailed Status

Completed12
Terminated6
Withdrawn3
Recruiting3
Active, not recruiting1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
27
Active
4
Success Rate
66.7%
Most Advanced
Phase 3

Trials by Phase

Phase 110 (37.0%)
Phase 212 (44.4%)
Phase 33 (11.1%)
N/A2 (7.4%)

Trials by Status

active_not_recruiting14%
withdrawn311%
not_yet_recruiting14%
completed1244%
recruiting311%
suspended14%
terminated622%

Recent Activity

Clinical Trials (27)

Showing 20 of 27 trialsScroll for more
NCT04645160Phase 1

Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers

Recruiting
NCT06053658Phase 2

Phase 2 Study of Combination Tivozanib and Nivolumab in Advanced Non-Clear Cell Renal Cell Carcinoma

Recruiting
NCT06661720Phase 3

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

Recruiting
NCT01885949Phase 2

Tivozanib + Enzalutamide in Adv Prostate Cancer

Terminated
NCT05000294Phase 1

Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types

Suspended
NCT07218692Phase 2

RP2 and Tivozanib for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy

Not Yet Recruiting
NCT04987203Phase 3

Study to Compare Tivozanib in Combination With Nivolumab to Tivozanib Monotherapy in Subjects With Renal Cell Carcinoma

Active Not Recruiting
NCT03970616Phase 1

A Study of Tivozanib in Combination With Durvalumab in Subjects With Advanced Hepatocellular Carcinoma

Terminated
NCT01769885Not Applicable

Tivozanib Before Surgery in Treating Patients With Localized Kidney Cancer

Withdrawn
NCT03136627Phase 1

Phase 1/2 Study of Tivozanib in Combination With Nivolumab in Subjects With RCC

Completed
NCT01853644Phase 2

Tivozanib in Recurrent, Platinum-Resistant Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Completed
NCT01673386Phase 2

A Subject Treatment Preference Study of Tivozanib Versus Sunitinib in Subjects With Metastatic RCC

Terminated
NCT01297244Phase 2

A Biomarker Study of Tivozanib in Subjects With Advanced Renal Cell Carcinoma

Completed
NCT01076010Phase 3

An Extension Treatment Protocol for Subjects Who Have Participated in a Study of Tivozanib Versus Sorafenib in Kidney Carcinoma (Protocol AV-951-09-301).

Completed
NCT01369433Not Applicable

A Rollover Protocol to Allow Continued Access to Tivozanib (AV 951) for Subjects Enrolled in Other Tivozanib Protocols

Terminated
NCT01782313Phase 2

A Phase II Study of Tivozanib in Patients With Metastatic and Non-resectable Soft Tissue Sarcomas

Completed
NCT01846871Phase 2

Tivozanib for Recurrent Glioblastoma

Completed
NCT01972516Phase 2

Tivozanib As Maintenance Therapy In GYN

Terminated
NCT01058655Phase 1

RAD001 and AV-951 in Patients With Refractory, Metastatic Colorectal Cancer

Completed
NCT01807156Phase 2

Phase II Trial of Tivozanib in Advanced Hepatocellular Cancer

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
27