Success Metrics

Clinical Success Rate
81.8%

Based on 9 completed trials

Completion Rate
82%(9/11)
Active Trials
6(29%)
Results Posted
44%(4 trials)
Terminated
2(10%)

Phase Distribution

Ph phase_1
7
33%
Ph early_phase_1
1
5%
Ph phase_3
2
10%
Ph phase_2
8
38%

Phase Distribution

8

Early Stage

8

Mid Stage

2

Late Stage

Phase Distribution18 total trials
Early Phase 1First-in-human
1(5.6%)
Phase 1Safety & dosage
7(38.9%)
Phase 2Efficacy & side effects
8(44.4%)
Phase 3Large-scale testing
2(11.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

64.3%

9 of 14 finished

Non-Completion Rate

35.7%

5 ended early

Currently Active

6

trials recruiting

Total Trials

21

all time

Status Distribution
Active(6)
Completed(9)
Terminated(5)
Other(1)

Detailed Status

Completed9
Recruiting4
Withdrawn3
Active, not recruiting2
Terminated2
Suspended1

Development Timeline

Analytics

Development Status

Total Trials
21
Active
6
Success Rate
81.8%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (5.6%)
Phase 17 (38.9%)
Phase 28 (44.4%)
Phase 32 (11.1%)

Trials by Status

recruiting419%
completed943%
suspended15%
active_not_recruiting210%
terminated210%
withdrawn314%

Recent Activity

Clinical Trials (21)

Showing 20 of 21 trialsScroll for more
NCT06785818

Long-term Follow up Local Registry Study of Kymriah in South Korea

Recruiting
NCT05888493Phase 3

A Phase III Trial Comparing Tisagenlecleucel to Standard of Care (SoC) in Adult Participants With r/r Follicular Lymphoma

Active Not Recruiting
NCT06408194Phase 1

Autologous CD22 CAR T Cells Following Commercial CD19 CAR T Cells in B Cell Malignancies

Recruiting
NCT05460533Phase 2

A Second Infusion (Early Reinfusion) of Tisagenlecleucel in Children and Young Adults With B-Cell Acute Lymphoblastic Leukemia(B-ALL)

Active Not Recruiting
NCT05633615Phase 2

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Recruiting
NCT04855253Phase 1

Ph I/II Study of E7777 Prior to CAR-T for R/R LBCL

Suspended
NCT04134117Phase 1

Tisagenlecleucel In Primary CNS Lymphoma

Completed
NCT05075603Phase 1

Relapsed/Refractory Large B-cell Lymphoma With NT-I7 Post-CD19 CAR T-cell Therapy

Completed
NCT03568461Phase 2

Efficacy and Safety of Tisagenlecleucel in Adult Patients With Refractory or Relapsed Follicular Lymphoma

Completed
NCT05541341

Effectiveness and Safety of Tisagenlecleucel Therapy in Brazilian Patients With B-lymphocyte Malignancies

Recruiting
NCT04890236Early Phase 1

Duvelisib Exposure to Enhance Immune Profiles of T Cells in Patients With Recurrent or Refractory Diffuse Large B-Cell Lymphoma, DEEP T CELLS Study

Completed
NCT03610724Phase 2

Phase II Open Label Trial to Determine Safety & Efficacy of Tisagenlecleucel in Pediatric Non-Hodgkin Lymphoma Patients

Completed
NCT02445248Phase 2

Study of Efficacy and Safety of CTL019 in Adult DLBCL Patients

Completed
NCT04156659Phase 2

Study of Tisagenlecleucel in Chinese Pediatric and Young Adult Subjects With Relapsed or Refractory B-cell ALL

Withdrawn
NCT03876028Phase 1

Study of Tisagenlecleucel in Combination With Ibrutinib in r/r Diffuse Large B-cell Lymphoma Patients

Terminated
NCT04225676Phase 2

Study of Efficacy and Safety of Reinfusion of Tisagenlecleucel in Pediatric and Young Adult Patients With Acute Lymphoblastic Leukemia (ALL)

Terminated
NCT05541328

Comparison of Clinical Outcomes Among Patients Treated With Tisagenlecleucel

Completed
NCT03630159Phase 1

Study of Tisagenlecleucel in Combination With Pembrolizumab in r/r Diffuse Large B-cell Lymphoma Patients

Completed
NCT02529813Phase 1

CD19-Specific T-cells in Treating Patients With Advanced Lymphoid Malignancies

Completed
NCT04456023Phase 2

Study of Tisagenlecleucel in Chinese Adult Patients With Relapsed or Refractory Diffuse Large B-cell Non-Hodgkin Lymphoma (DLBCL)

Withdrawn

Drug Details

Intervention Type
OTHER
Total Trials
21