Success Metrics

Clinical Success Rate
65.5%

Based on 19 completed trials

Completion Rate
66%(19/29)
Active Trials
24(41%)
Results Posted
111%(21 trials)
Terminated
10(17%)

Phase Distribution

Ph phase_1
20
34%
Ph phase_3
9
15%
Ph phase_2
30
51%

Phase Distribution

20

Early Stage

30

Mid Stage

9

Late Stage

Phase Distribution59 total trials
Phase 1Safety & dosage
20(33.9%)
Phase 2Efficacy & side effects
30(50.8%)
Phase 3Large-scale testing
9(15.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

57.6%

19 of 33 finished

Non-Completion Rate

42.4%

14 ended early

Currently Active

24

trials recruiting

Total Trials

59

all time

Status Distribution
Active(24)
Completed(19)
Terminated(14)
Other(2)

Detailed Status

Completed19
Active, not recruiting16
Terminated10
Recruiting8
Withdrawn4
unknown2

Development Timeline

Analytics

Development Status

Total Trials
59
Active
24
Success Rate
65.5%
Most Advanced
Phase 3

Trials by Phase

Phase 120 (33.9%)
Phase 230 (50.8%)
Phase 39 (15.3%)

Trials by Status

unknown23%
active_not_recruiting1627%
completed1932%
terminated1017%
withdrawn47%
recruiting814%

Recent Activity

Clinical Trials (59)

Showing 20 of 59 trialsScroll for more
NCT05009069Phase 2

A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer

Active Not Recruiting
NCT03784326Phase 2

Phase I/II Study of Perioperative Chemotherapy Plus Immunotherapy Followed by Surgery in Localized Esophageal and Gastroesophageal Adenocarcinoma

Active Not Recruiting
NCT05645692Phase 2

A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer

Active Not Recruiting
NCT04543617Phase 3

A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy

Active Not Recruiting
NCT04929223Phase 1

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

Recruiting
NCT04524871Phase 1

A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

Recruiting
NCT05286801Phase 1

Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors

Active Not Recruiting
NCT05862285Phase 3

A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study

Recruiting
NCT05825625Phase 2

NeoTRACK - Dissection of IO Efficacy in NSCLC by Longitudinal tracKing

Active Not Recruiting
NCT06267001Phase 3

A Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Non-small Cell Lung Cancer Who Have Received Adjuvant Platinum-based Chemotherapy

Terminated
NCT05798663Phase 2

Atezolizumab Immunotherapy With or Without Tiragolumab for Patients With Unresectable Stage III NSCLC

Active Not Recruiting
NCT04513925Phase 3

A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC)

Completed
NCT04619797Phase 2

A Study of Tiragolumab in Combination With Atezolizumab Plus Pemetrexed and Carboplatin/Cisplatin Versus Pembrolizumab Plus Pemetrexed and Carboplatin/Cisplatin in Participants With Previously Untreated Advanced Non-Squamous Non-Small Cell Lung Cancer

Completed
NCT05681039Phase 2

Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients With Newly Diagnosed PD-L1 CPS Positive Resectable Stage 3-4 Oral Cavity Squamous Cell Carcinoma (OCSCC).

Active Not Recruiting
NCT03337698Phase 1

A Study Of Multiple Immunotherapy-Based Treatment Combinations In Participants With Metastatic Non-Small Cell Lung Cancer (Morpheus- Non-Small Cell Lung Cancer)

Terminated
NCT05805501Phase 2

A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma

Active Not Recruiting
NCT05394337Phase 1

Neoadjuvant PD-1 Plus TIGIT Blockade in Patients With Cisplatin-Ineligible Operable High-Risk Urothelial Carcinoma

Recruiting
NCT04665843Phase 2

A Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and Neck

Completed
NCT03563716Phase 2

A Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Completed
NCT03554083Phase 2

Vemurafenib, Cobimetinib, Atezolizumab, and Tiragolumab in Treating Patients With High-Risk Stage III Melanoma

Completed

Drug Details

Intervention Type
DRUG
Total Trials
59