Success Metrics

Clinical Success Rate
90.9%

Based on 20 completed trials

Completion Rate
91%(20/22)
Active Trials
3(10%)
Results Posted
45%(9 trials)
Terminated
2(7%)

Phase Distribution

Ph phase_4
3
10%
Ph not_applicable
7
24%
Ph phase_1
5
17%
Ph phase_3
2
7%
Ph early_phase_1
4
14%
Ph phase_2
8
28%

Phase Distribution

9

Early Stage

8

Mid Stage

5

Late Stage

Phase Distribution29 total trials
Early Phase 1First-in-human
4(13.8%)
Phase 1Safety & dosage
5(17.2%)
Phase 2Efficacy & side effects
8(27.6%)
Phase 3Large-scale testing
2(6.9%)
Phase 4Post-market surveillance
3(10.3%)
N/ANon-phased studies
7(24.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

83.3%

20 of 24 finished

Non-Completion Rate

16.7%

4 ended early

Currently Active

3

trials recruiting

Total Trials

29

all time

Status Distribution
Active(3)
Completed(20)
Terminated(4)
Other(2)

Detailed Status

Completed20
Recruiting3
Withdrawn2
Terminated2
unknown2

Development Timeline

Analytics

Development Status

Total Trials
29
Active
3
Success Rate
90.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (13.8%)
Phase 15 (17.2%)
Phase 28 (27.6%)
Phase 32 (6.9%)
Phase 43 (10.3%)
N/A7 (24.1%)

Trials by Status

recruiting310%
withdrawn27%
terminated27%
unknown27%
completed2069%

Recent Activity

Clinical Trials (29)

Showing 20 of 29 trialsScroll for more
NCT06298344Early Phase 1

The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease

Completed
NCT06322212Early Phase 1

Type 2 Diabetes and Blood Brain Barrier Improvement

Recruiting
NCT07046429Not Applicable

Affect of Melatonin on Sleep and Cognition in Cirrhosis

Recruiting
NCT06326996Early Phase 1

Thiamine Intervention and Coronary Artery Bypass Grafting

Recruiting
NCT02974257Phase 2

Thiamine vs. Placebo to Increase Oxygen Consumption After Cardiac Arrest

Terminated
NCT03509662Phase 2

Vitamin C in Post-cardiac Arrest

Completed
NCT03263442Phase 2

High Dose Intravenous Thiamine for the Prevention of Delirium in Allogeneic Hematopoietic Stem Cell Transplantation

Completed
NCT03422159Phase 2

Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.

Completed
NCT03228030Phase 1

Thiamine Supplementation in Heart Failure: a Pilot Randomized Controlled Crossover Trial

Completed
NCT04977557Not Applicable

Thiamine in Patients With Clinically Suspected Dry Beriberi

Completed
NCT04893993Phase 4

PBC Induced Fatigue Treated With Thiamine

Unknown
NCT03509350Phase 3

Vitamin C, Thiamine, and Steroids in Sepsis

Completed
NCT03634735Phase 4

Thiamin Against Robust IBD Fatigue

Completed
NCT03432572Early Phase 1

Investigating Oral Agents for Urine Staining to Facilitate Intraoperative Observation of Ureteral Jets

Completed
NCT03333278Phase 2

The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial

Completed
NCT03122678Phase 1

Thiamine Supplementation in Patients With Septic Shock

Withdrawn
NCT03335124Phase 4

The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock

Terminated
NCT03649009Not Applicable

Thiamine As An Adjuvant Therapy For Hyperlactatemia In Septic Shock Patients

Unknown
NCT01381354Phase 1

Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)

Completed
NCT01462279Not Applicable

Effect of Thiamine on Oxygen Utilization (VO2) in Critical Illness

Completed

Drug Details

Intervention Type
DIETARY SUPPLEMENT
Total Trials
29