Success Metrics

Clinical Success Rate
66.9%

Based on 160 completed trials

Completion Rate
67%(160/239)
Active Trials
51(15%)
Results Posted
86%(138 trials)
Terminated
79(24%)

Phase Distribution

Ph phase_1
77
23%
Ph phase_2
144
43%
Ph not_applicable
55
16%
Ph phase_4
1
0%
Ph phase_3
29
9%
Ph early_phase_1
24
7%

Phase Distribution

101

Early Stage

144

Mid Stage

30

Late Stage

Phase Distribution330 total trials
Early Phase 1First-in-human
24(7.3%)
Phase 1Safety & dosage
77(23.3%)
Phase 2Efficacy & side effects
144(43.6%)
Phase 3Large-scale testing
29(8.8%)
Phase 4Post-market surveillance
1(0.3%)
N/ANon-phased studies
55(16.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

61.8%

160 of 259 finished

Non-Completion Rate

38.2%

99 ended early

Currently Active

51

trials recruiting

Total Trials

336

all time

Status Distribution
Active(51)
Completed(160)
Terminated(99)
Other(26)

Detailed Status

Completed160
Terminated79
Active, not recruiting38
unknown25
Withdrawn20
Recruiting13

Development Timeline

Analytics

Development Status

Total Trials
336
Active
51
Success Rate
66.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 124 (7.3%)
Phase 177 (23.3%)
Phase 2144 (43.6%)
Phase 329 (8.8%)
Phase 41 (0.3%)
N/A55 (16.7%)

Trials by Status

terminated7924%
recruiting134%
active_not_recruiting3811%
suspended10%
unknown257%
withdrawn206%
completed16048%

Recent Activity

Clinical Trials (336)

Showing 20 of 336 trialsScroll for more
NCT03776487Phase 2

Nivolumab, Ipilimumab and Chemoradiation in Treating Patients With Resectable Gastric Cancer

Active Not Recruiting
NCT04628767Phase 2

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Recruiting
NCT02015117Phase 1

Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

Active Not Recruiting
NCT02180867Phase 2

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Active Not Recruiting
NCT02775851Phase 2

Pembrolizumab in Treating Patients With Desmoplastic Melanoma That Can or Cannot Be Removed by Surgery

Active Not Recruiting
NCT03698019Phase 2

A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma

Active Not Recruiting
NCT01167712Phase 3

Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Active Not Recruiting
NCT03361436Phase 1

Eribulin and Radiation Therapy in Treating Patients With Retroperitoneal Liposarcoma That Can Be Removed by Surgery

Active Not Recruiting
NCT00980460Phase 3

Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer

Active Not Recruiting
NCT04197934Phase 1

WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

Active Not Recruiting
NCT03433469Phase 2

Osimertinib in Treating Participants With Stage I-IIIA EGFR-mutant Non-small Cell Lung Cancer Before Surgery

Active Not Recruiting
NCT02437851Phase 2

Surgery in Treating Patients With Early Stage Anal Canal or Perianal Cancer and HIV Infection

Active Not Recruiting
NCT03197506Phase 2

Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma

Active Not Recruiting
NCT03391869Phase 3

Nivolumab and Ipilimumab With or Without Local Consolidation Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer

Active Not Recruiting
NCT03493425Phase 2

Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery

Recruiting
NCT02047474Phase 2

Combination Chemotherapy Before and After Surgery in Treating Patients With Localized Pancreatic Cancer

Completed
NCT03896568Phase 1

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

Recruiting
NCT04144023Phase 1

A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ

Recruiting
NCT03359954Phase 2

Radiation Therapy Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Breast Cancer

Active Not Recruiting
NCT04721132Phase 2

Atezolizumab and Bevacizumab Before Surgery for the Treatment of Resectable Liver Cancer

Active Not Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
336