Success Metrics

Clinical Success Rate
67.4%

Based on 163 completed trials

Completion Rate
67%(163/242)
Active Trials
48(14%)
Results Posted
85%(138 trials)
Terminated
79(24%)

Phase Distribution

Ph phase_2
144
43%
Ph early_phase_1
24
7%
Ph phase_3
29
9%
Ph not_applicable
55
16%
Ph phase_4
1
0%
Ph phase_1
77
23%

Phase Distribution

101

Early Stage

144

Mid Stage

30

Late Stage

Phase Distribution330 total trials
Early Phase 1First-in-human
24(7.3%)
Phase 1Safety & dosage
77(23.3%)
Phase 2Efficacy & side effects
144(43.6%)
Phase 3Large-scale testing
29(8.8%)
Phase 4Post-market surveillance
1(0.3%)
N/ANon-phased studies
55(16.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

62.2%

163 of 262 finished

Non-Completion Rate

37.8%

99 ended early

Currently Active

48

trials recruiting

Total Trials

336

all time

Status Distribution
Active(48)
Completed(163)
Terminated(99)
Other(26)

Detailed Status

Completed163
Terminated79
Active, not recruiting35
unknown25
Withdrawn20
Recruiting13

Development Timeline

Analytics

Development Status

Total Trials
336
Active
48
Success Rate
67.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 124 (7.3%)
Phase 177 (23.3%)
Phase 2144 (43.6%)
Phase 329 (8.8%)
Phase 41 (0.3%)
N/A55 (16.7%)

Trials by Status

recruiting134%
active_not_recruiting3510%
completed16349%
suspended10%
terminated7924%
unknown257%
withdrawn206%

Recent Activity

Clinical Trials (336)

Showing 20 of 336 trialsScroll for more
NCT01556243Phase 2

Breast-Conserving Surgery and Radiation Therapy in Patients With Multiple Ipsilateral Breast Cancer

Completed
NCT04628767Phase 2

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Recruiting
NCT05110781Phase 2

Atezolizumab Before Surgery for the Treatment of Regionally Metastatic Head and Neck Squamous Cell Cancer With an Unknown or Historic Primary Site

Terminated
NCT00945009Phase 3

Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor

Completed
NCT00352534Phase 3

Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' Tumor

Completed
NCT03698019Phase 2

A Study to Compare the Administration of Pembrolizumab After Surgery Versus Administration Both Before and After Surgery for High-Risk Melanoma

Active Not Recruiting
NCT01196390Phase 3

Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer

Completed
NCT02210117Early Phase 1

Nivolumab With or Without Bevacizumab or Ipilimumab Before Surgery in Treating Patients With Metastatic Kidney Cancer That Can Be Removed by Surgery

Active Not Recruiting
NCT02775851Phase 2

Pembrolizumab in Treating Patients With Desmoplastic Melanoma That Can or Cannot Be Removed by Surgery

Active Not Recruiting
NCT01167712Phase 3

Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Active Not Recruiting
NCT04759911Phase 2

Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid Cancer

Active Not Recruiting
NCT02689427Phase 2

Enzalutamide and Paclitaxel Before Surgery in Treating Patients With Stage I-III Androgen Receptor-Positive Triple-Negative Breast Cancer

Completed
NCT01891318Phase 1

Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study

Recruiting
NCT04105374Phase 2

Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma

Withdrawn
NCT03493425Phase 2

Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery

Recruiting
NCT02180867Phase 2

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Active Not Recruiting
NCT05296421Not Applicable

Investigating Targetable Metabolic Pathways Sustaining Pancreatic Cancer

Recruiting
NCT00980460Phase 3

Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer

Active Not Recruiting
NCT02589522Phase 1

Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors

Active Not Recruiting
NCT04973683Phase 1

AL101 Before Surgery for the Treatment of Notch Activated Adenoid Cystic Cancer

Active Not Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
336