Success Metrics

Clinical Success Rate
67.9%

Based on 167 completed trials

Completion Rate
68%(167/246)
Active Trials
45(13%)
Results Posted
83%(139 trials)
Terminated
79(24%)

Phase Distribution

Ph early_phase_1
24
7%
Ph not_applicable
55
16%
Ph phase_3
29
9%
Ph phase_1
77
23%
Ph phase_2
144
43%
Ph phase_4
1
0%

Phase Distribution

101

Early Stage

144

Mid Stage

30

Late Stage

Phase Distribution330 total trials
Early Phase 1First-in-human
24(7.3%)
Phase 1Safety & dosage
77(23.3%)
Phase 2Efficacy & side effects
144(43.6%)
Phase 3Large-scale testing
29(8.8%)
Phase 4Post-market surveillance
1(0.3%)
N/ANon-phased studies
55(16.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

62.8%

167 of 266 finished

Non-Completion Rate

37.2%

99 ended early

Currently Active

45

trials recruiting

Total Trials

336

all time

Status Distribution
Active(45)
Completed(167)
Terminated(99)
Other(25)

Detailed Status

Completed167
Terminated79
Active, not recruiting33
unknown25
Withdrawn20
Recruiting12

Development Timeline

Analytics

Development Status

Total Trials
336
Active
45
Success Rate
67.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 124 (7.3%)
Phase 177 (23.3%)
Phase 2144 (43.6%)
Phase 329 (8.8%)
Phase 41 (0.3%)
N/A55 (16.7%)

Trials by Status

active_not_recruiting3310%
recruiting124%
terminated7924%
unknown257%
completed16750%
withdrawn206%

Recent Activity

Clinical Trials (336)

Showing 20 of 336 trialsScroll for more
NCT04628767Phase 2

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Recruiting
NCT05030298Phase 1

Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma Trial

Recruiting
NCT03896568Phase 1

MSC-DNX-2401 in Treating Patients With Recurrent High-Grade Glioma

Recruiting
NCT02015117Phase 1

Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

Active Not Recruiting
NCT03197506Phase 2

Pembrolizumab and Standard Therapy in Treating Patients With Glioblastoma

Active Not Recruiting
NCT03776487Phase 2

Nivolumab, Ipilimumab and Chemoradiation in Treating Patients With Resectable Gastric Cancer

Active Not Recruiting
NCT03410043Phase 2

Osimertinib, Surgery, and Radiation Therapy in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer With EGFR Mutations, NORTHSTAR Study

Active Not Recruiting
NCT03391869Phase 3

Nivolumab and Ipilimumab With or Without Local Consolidation Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer

Active Not Recruiting
NCT05316688Phase 1

A Fluorescent Tumor Marking Agent, Tozuleristide, for Imaging Oral Cavity Squamous Cell Cancer and High-Grade Oral Cavity Dysplasia During Surgery

Terminated
NCT04428671Phase 1

Cemiplimab Before and After Surgery for the Treatment of High Risk Cutaneous Squamous Cell Cancer

Active Not Recruiting
NCT03493425Phase 2

Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery

Active Not Recruiting
NCT02812420Early Phase 1

Durvalumab and Tremelimumab in Treating Patients With Muscle-Invasive, High-Risk Urothelial Cancer That Cannot Be Treated With Cisplatin-Based Therapy Before Surgery

Active Not Recruiting
NCT03359954Phase 2

Radiation Therapy Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Breast Cancer

Active Not Recruiting
NCT04721132Phase 2

Atezolizumab and Bevacizumab Before Surgery for the Treatment of Resectable Liver Cancer

Active Not Recruiting
NCT02337686Phase 2

Pembrolizumab in Treating Patients With Recurrent Glioblastoma

Active Not Recruiting
NCT03126916Phase 3

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Recruiting
NCT00977457Phase 1

Genetic Testing in Predicting Biomarkers of Recurrence in Patients With Prostate Cancer Undergoing Surgery

Active Not Recruiting
NCT03943173Early Phase 1

Olaparib in Treating Patients With Newly Diagnosed BRCA-Mutant Ovarian, Primary Peritoneal, or Fallopian Cancer Before Surgery

Active Not Recruiting
NCT04199026Not Applicable

Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

Recruiting
NCT02231775Phase 2

Dabrafenib and Trametinib Before and After Surgery in Treating Patients With Stage IIIB-C Melanoma With BRAF V600 Mutation

Active Not Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
336