Success Metrics

Clinical Success Rate
83.3%

Based on 35 completed trials

Completion Rate
83%(35/42)
Active Trials
1(2%)
Results Posted
11%(4 trials)
Terminated
7(15%)

Phase Distribution

Ph phase_2
12
26%
Ph phase_1
34
72%

Phase Distribution

34

Early Stage

12

Mid Stage

0

Late Stage

Phase Distribution46 total trials
Phase 1Safety & dosage
34(73.9%)
Phase 2Efficacy & side effects
12(26.1%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

81.4%

35 of 43 finished

Non-Completion Rate

18.6%

8 ended early

Currently Active

1

trials recruiting

Total Trials

47

all time

Status Distribution
Active(1)
Completed(35)
Terminated(8)
Other(3)

Detailed Status

Completed35
Terminated7
unknown3
Active, not recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
47
Active
1
Success Rate
83.3%
Most Advanced
Phase 2

Trials by Phase

Phase 134 (73.9%)
Phase 212 (26.1%)

Trials by Status

completed3574%
active_not_recruiting12%
unknown36%
withdrawn12%
terminated715%

Recent Activity

Clinical Trials (47)

Showing 20 of 47 trialsScroll for more
NCT00466531Phase 1

Treatment of Relapsed or Chemotherapy Refractory Chronic Lymphocytic Leukemia or Indolent B Cell Lymphoma Using Autologous T Cells Genetically Targeted to the B Cell Specific Antigen CD19

Active Not Recruiting
NCT00562640Phase 1

Autologous T Cells With or Without Cyclophosphamide and Fludarabine in Treating Patients With Recurrent or Persistent Advanced Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer (Fludarabine Treatment Closed as of 12/01/2009)

Completed
NCT00639639Phase 1

Vaccine Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Completed
NCT00945269Phase 1

Therapeutic Autologous Lymphocytes, Aldesleukin, and Denileukin Diftitox in Treating Patients With Stage III-IV Melanoma

Terminated
NCT00005803Phase 1

Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma

Completed
NCT00003727Phase 2

Chemotherapy and Peripheral Stem Cell Transplantation Followed by Immunotherapy in Treating Patients With Chronic Myelogenous Leukemia

Completed
NCT00046852Phase 1

Chemotherapy and Peripheral Stem Cell Transplantation Followed By Immunotherapy in Treating Patients With Multiple Myeloma

Completed
NCT00730613Phase 1

Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent or Refractory High-Grade Malignant Glioma

Completed
NCT01943188Phase 1

Stereotactic Body Radiation Therapy and T-Cell Infusion in Treating Patients With Metastatic Kidney Cancer

Terminated
NCT00553306Phase 1

Laboratory-Treated T Cells and Aldesleukin After Cyclophosphamide in Treating Patients With Stage IV Melanoma

Completed
NCT00027807Phase 1

Biological Therapy in Treating Women With Stage IV Breast Cancer

Completed
NCT00020722Phase 2

Chemotherapy Followed by Peripheral Stem Cell Transplantation Plus Biological Therapy in Treating Women With Stage IV Breast Cancer

Terminated
NCT00317759Phase 1

Fludarabine Followed By Adoptive Immunotherapy in Treating Patients With Stage IV Melanoma

Completed
NCT00022230Phase 1

Combination Chemotherapy Plus Biological Therapy in Treating Patients With Stage II or Stage III Breast Cancer

Withdrawn
NCT00019357Phase 1

Interleukin-2 Plus Activated White Blood Cells in Treating Patients With Cancer That Has Not Responded to Chemotherapy or Radiation Therapy

Completed
NCT00244946Phase 1

Combination Chemotherapy Followed By Autologous Stem Cell Transplant, and White Blood Cell Infusions in Treating Patients With Non-Hodgkin's Lymphoma

Completed
NCT00621452Phase 1

Genetically Engineered Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Indolent B-Cell Non-Hodgkin Lymphoma

Completed
NCT01339663Phase 1

Vaccine Therapy Following Therapeutic Autologous Lymphocytes and Cyclophosphamide in Treating Patients With Metastatic Melanoma

Completed
NCT00002589Phase 2

Lymphocyte Therapy in Treating Patients With Kidney Cancer

Unknown
NCT00101309Phase 1

Vaccine Therapy and Interleukin-2 in Treating Young Patients With Relapsed or Refractory Ewing's Sarcoma or Neuroblastoma

Unknown

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
47