Dietary Supplement
Tetrahydrobiopterin (BH4)
Tetrahydrobiopterin (BH4) is a dietary supplement with 5 clinical trials. Historical success rate of 60.0%.
Total Trials
5
Max Phase
—
Type
DIETARY SUPPLEMENT
Molecule
—
Success Metrics
Clinical Success Rate
60.0%
Based on 3 completed trials
Completion Rate
60%(3/5)
Active Trials
0(0%)
Results Posted
67%(2 trials)
Terminated
2(40%)
Phase Distribution
Ph early_phase_1
1
20%
Ph phase_1
1
20%
Ph phase_2
2
40%
Ph not_applicable
1
20%
Phase Distribution
2
Early Stage
2
Mid Stage
0
Late Stage
Phase Distribution5 total trials
Early Phase 1First-in-human
1(20.0%)
Phase 1Safety & dosage
1(20.0%)
Phase 2Efficacy & side effects
2(40.0%)
N/ANon-phased studies
1(20.0%)
Highest Phase Reached
Phase 2Trial Status & Enrollment
Completion Rate
60.0%
3 of 5 finished
Non-Completion Rate
40.0%
2 ended early
Currently Active
0
trials recruiting
Total Trials
5
all time
Status Distribution
Completed(3)
Terminated(2)
Detailed Status
Completed3
Terminated2
Development Timeline
Analytics
Development Status
Total Trials
5
Active
0
Success Rate
60.0%
Most Advanced
Phase 2
Trials by Phase
Early Phase 11 (20.0%)
Phase 11 (20.0%)
Phase 22 (40.0%)
N/A1 (20.0%)
Trials by Status
terminated240%
completed360%
Recent Activity
0 active trials
Showing 5 of 5
completedearly_phase_1
Exercise and NO in HFrEF
NCT03136029
terminatedphase_1
Response to Phenylketonuria to Tetrahydrobiopterin (BH4)
NCT00244218
completedphase_2
Long Term Nitric Oxide Bioavailability on Vascular Health in Chronic Obstructive Pulmonary Disease
NCT02774226
completednot_applicable
Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)
NCT01398943
terminatedphase_2
Long-Term Tetrahydrobiopterin Treatment in PKU Patients of 0-18 Years - Study on Phenylalanine Tolerance and Safety
NCT00432822
Clinical Trials (5)
Showing 5 of 5 trials
NCT03136029Early Phase 1
Exercise and NO in HFrEF
NCT00244218Phase 1
Response to Phenylketonuria to Tetrahydrobiopterin (BH4)
NCT02774226Phase 2
Long Term Nitric Oxide Bioavailability on Vascular Health in Chronic Obstructive Pulmonary Disease
NCT01398943Not Applicable
Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)
NCT00432822Phase 2
Long-Term Tetrahydrobiopterin Treatment in PKU Patients of 0-18 Years - Study on Phenylalanine Tolerance and Safety
All 5 trials loaded
Drug Details
- Intervention Type
- DIETARY SUPPLEMENT
- Total Trials
- 5