Success Metrics

Clinical Success Rate
86.7%

Based on 13 completed trials

Completion Rate
87%(13/15)
Active Trials
9(24%)
Results Posted
54%(7 trials)
Terminated
2(5%)

Phase Distribution

Ph phase_3
5
13%
Ph not_applicable
4
11%
Ph phase_2
7
18%
Ph phase_4
13
34%
Ph phase_1
3
8%

Phase Distribution

3

Early Stage

7

Mid Stage

18

Late Stage

Phase Distribution32 total trials
Phase 1Safety & dosage
3(9.4%)
Phase 2Efficacy & side effects
7(21.9%)
Phase 3Large-scale testing
5(15.6%)
Phase 4Post-market surveillance
13(40.6%)
N/ANon-phased studies
4(12.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

86.7%

13 of 15 finished

Non-Completion Rate

13.3%

2 ended early

Currently Active

9

trials recruiting

Total Trials

38

all time

Status Distribution
Active(9)
Completed(13)
Terminated(2)
Other(14)

Detailed Status

unknown14
Completed13
Active, not recruiting5
Recruiting4
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
38
Active
9
Success Rate
86.7%
Most Advanced
Phase 4

Trials by Phase

Phase 13 (9.4%)
Phase 27 (21.9%)
Phase 35 (15.6%)
Phase 413 (40.6%)
N/A4 (12.5%)

Trials by Status

recruiting411%
unknown1437%
active_not_recruiting513%
completed1334%
terminated25%

Recent Activity

Clinical Trials (38)

Showing 20 of 38 trialsScroll for more
NCT05652478Phase 2

Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study

Recruiting
NCT05979311Phase 3

A Study to Evaluate the Efficacy, Safety, and Tolerability of Using an Oral Once-daily 2 Drug Regimen Compared to an Oral Once-daily 3 Drug Regimen for the Treatment of Human Immunodeficiency Virus (HIV)-1 in Adults Who Have Not Previously Taken Antiretroviral Therapy

Active Not Recruiting
NCT04891770Phase 2

Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB)

Completed
NCT04439539Phase 2

A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection

Completed
NCT02995252

The HOPE Study: Characterizing Patients With Hepatitis B and C

Recruiting
NCT05275023Phase 2

An Efficacy and Safety Study of a Combination of JNJ-73763989, Nucleos(t)Ide Analogs (NA), and a Programmed Cell Death Protein Receptor-1 (PD-1) Inhibitor in Chronic Hepatitis B Participants

Completed
NCT03804372Phase 2

The Incidence of Hepatitis B in Diffuse Large B-Cell Lymphoma/Chronic Lymphoid Leukemia HBsAg-positive Treated With Rituximab, Chemotherapy and Tenofovir Alafenamide

Terminated
NCT03933384Phase 4

Tenofovir Alafenamide Versus Entecavir for the Treatment of Chronic Hepatitis B

Recruiting
NCT03753074Phase 4

Effectiveness of TAF in Reducing Clinical Events in CHB Patients Beyond Treatment Indications by Current Guidelines

Active Not Recruiting
NCT03920618Not Applicable

Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF

Recruiting
NCT04619082Phase 4

TAF to Prevent HBV Reactivation in Cancer Patients

Active Not Recruiting
NCT04937881Phase 3

PK of TAF and TDF for PrEP in Pregnant and Postpartum Women

Completed
NCT03510468Phase 1

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers (YODA)

Completed
NCT03887702Phase 3

Prophylactic Antiviral Therapy in Patients With Current or Past Hepatitis B Virus Infection Receiving Anti-Cancer Therapy for Solid Tumors

Terminated
NCT03471624Phase 4

Treatment Outcomes in Chronic Hepatitis B Patients on Sequential Therapy With Tenofovir Alafenamide (TAF)

Completed
NCT04939441Phase 4

Regression of Liver Fibrosis by Tenofovir Alafenamide (TAF)

Unknown
NCT03640728

The Efficacy and Safety of Nucleos(t)Ide Analogues in the Treatment of HBV-related Acute-on-chronic Liver Failure

Unknown
NCT05423834

Chronic Kidney Disease Progression in Chronic Hepatitis B Patients on Tenofovir Alafenamide (TAF) Versus Entecavir

Active Not Recruiting
NCT03122262Phase 3

ADVANCE Study of DTG + TAF + FTC vs DTG + TDF + FTC and EFV + TDF+FTC in First-line Antiretroviral Therapy

Completed
NCT05467553Phase 2

A Study to Compare P1101 Plus TAF With or Without UDCA in Patients With HBV and HDV Co-Infection

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
38