Success Metrics

Clinical Success Rate
100.0%

Based on 23 completed trials

Completion Rate
100%(23/23)
Active Trials
1(3%)
Results Posted
70%(16 trials)

Phase Distribution

Ph phase_2
5
17%
Ph phase_3
12
40%
Ph phase_4
5
17%
Ph early_phase_1
1
3%
Ph phase_1
5
17%

Phase Distribution

6

Early Stage

5

Mid Stage

17

Late Stage

Phase Distribution28 total trials
Early Phase 1First-in-human
1(3.6%)
Phase 1Safety & dosage
5(17.9%)
Phase 2Efficacy & side effects
5(17.9%)
Phase 3Large-scale testing
12(42.9%)
Phase 4Post-market surveillance
5(17.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

100.0%

23 of 23 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

1

trials recruiting

Total Trials

30

all time

Status Distribution
Active(3)
Completed(23)
Other(4)

Detailed Status

Completed23
unknown4
Not yet recruiting1
Enrolling by invitation1
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
30
Active
1
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (3.6%)
Phase 15 (17.9%)
Phase 25 (17.9%)
Phase 312 (42.9%)
Phase 45 (17.9%)

Trials by Status

completed2377%
unknown413%
not_yet_recruiting13%
enrolling_by_invitation13%
recruiting13%

Recent Activity

Clinical Trials (30)

Showing 20 of 30 trialsScroll for more
NCT07668934Phase 4

TAF in Early/Middle Pregnancy With CHB

Enrolling By Invitation
NCT06963710Phase 2

A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)

Recruiting
NCT07553767Early Phase 1

Efficacy and Safety of Pegylated Interferon Alpha-2β in Patients With Hepatitis B-related Hepatocellular Carcinoma After Radical Resection

Not Yet Recruiting
NCT05612581Phase 1

A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection

Completed
NCT03903796Phase 3

Study of the Efficacy and Safety of HS-10234 in Patients With Chronic Hepatitis B Virus Infection

Completed
NCT02836249Phase 3

Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Positive Hepatitis B (China)

Completed
NCT02836236Phase 3

Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Negative Hepatitis B (China)

Completed
NCT04846491Phase 3

A Study of Peginterferon Alfa-2b Combined With TDF in Patients With Chronic Hepatitis B

Completed
NCT01940471Phase 3

Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Positive for Hepatitis B e Antigen

Completed
NCT01940341Phase 3

Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Negative for Hepatitis B e Antigen

Completed
NCT01448616Phase 4

Effect of Tenofovir on Genital Herpes Simplex Virus (HSV) Shedding

Completed
NCT02862548Phase 2

Efficacy and Safety of Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF)-Containing Regimens in Participants With Chronic Hepatitis B Virus (HBV) Infection and Stage 2 or Greater Chronic Kidney Disease Who Have Received a Liver Transplant

Completed
NCT03596697Phase 1

A Study in Healthy Volunteers

Completed
NCT04650828

TDF Combined With LDT for the Treatment of HBeAg-positive Hepatitis B Patients With Poor Response to TDF for 12 Months

Unknown
NCT02979613Phase 3

Study to Evaluate Efficacy and Safety of Switching From TDF to TAF in Adults With Chronic Hepatitis B Who Are Virologically Suppressed

Completed
NCT02579382Phase 2

Study to Evaluate the Safety, Tolerability, and Efficacy of Vesatolimod in Combination With Tenofovir Disoproxil Fumarate (TDF) in Adults With Chronic Hepatitis B (CHB) Infection Who Are Currently Not Being Treated

Completed
NCT04303598Phase 3

Phase III Clinical Study of Azvudine in Hiv-infected Treatment Naive Patients

Unknown
NCT02616783Phase 3

Switching From a Tenofovir Disoproxil Fumarate (TDF) Containing Regimen to Elvitegravir/Cobicistat/Emtricitabine/ Tenofovir Alafenamide (E/C/F/TAF) Fixed-Dose Combination (FDC) in Virologically-Suppressed, HIV-1 Infected Adults Aged ≥ 60 Years

Completed
NCT02081469Phase 4

Prophylaxis of CHB Patients With Malignant Tumor Receiving Chemotherapy

Completed
NCT04135235

Effect and Safety of Propofol Fumarate for Mother-to-child Blocking of Hepatitis B

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
30