Success Metrics

Clinical Success Rate
94.1%

Based on 16 completed trials

Completion Rate
94%(16/17)
Active Trials
3(15%)
Results Posted
31%(5 trials)
Terminated
1(5%)

Phase Distribution

Ph phase_1
9
45%
Ph phase_2
3
15%
Ph phase_3
7
35%
Ph early_phase_1
1
5%

Phase Distribution

10

Early Stage

3

Mid Stage

7

Late Stage

Phase Distribution20 total trials
Early Phase 1First-in-human
1(5.0%)
Phase 1Safety & dosage
9(45.0%)
Phase 2Efficacy & side effects
3(15.0%)
Phase 3Large-scale testing
7(35.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

94.1%

16 of 17 finished

Non-Completion Rate

5.9%

1 ended early

Currently Active

3

trials recruiting

Total Trials

20

all time

Status Distribution
Active(3)
Completed(16)
Terminated(1)

Detailed Status

Completed16
Recruiting2
Terminated1
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
20
Active
3
Success Rate
94.1%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (5.0%)
Phase 19 (45.0%)
Phase 23 (15.0%)
Phase 37 (35.0%)

Trials by Status

completed1680%
recruiting210%
terminated15%
active_not_recruiting15%

Recent Activity

Clinical Trials (20)

Showing 20 of 20 trials
NCT04652882Phase 3

Evaluating the Effects of Tasimelteon vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD)

Recruiting
NCT05922995Early Phase 1

The Effects of Tasimelteon in Participants With REM Behavior Disorder (RBD)

Terminated
NCT06701396Phase 3

Evaluating the Effects of Tasimelteon Vs. Placebo in Delayed Sleep-Wake Phase Disorder (DSWPD) and the CRY1Δ11 Variant

Recruiting
NCT01218789Phase 3

Safety Study of Tasimelteon for Treatment of Non-24-Hour-Sleep-Wake Disorder in Blind Individuals With No Light Perception

Active Not Recruiting
NCT06323655Phase 1

Evaluation of Next-Day Residual Effects of Tasimelteon Compared With Placebo and Active Control in Healthy Subjects

Completed
NCT02776215Phase 1

Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents

Completed
NCT03373201Phase 3

Evaluating the Effects of Tasimelteon vs. Placebo on Jet Lag Type Insomnia

Completed
NCT02231008Phase 2

Evaluating the Effects of Tasimelteon vs Placebo on Sleep Disturbances in SMS

Completed
NCT03291041Phase 2

A Proof of Concept Study to Evaluate the Effects of Tasimelteon and Placebo in Travelers With Jet Lag Disorder

Completed
NCT01428661Phase 2

Melatonin Agonist Effects of Tasimelteon Versus Placebo in Patients With Major Depressive Disorder

Completed
NCT01429116Phase 3

Tasimelteon for the Treatment of Non-24-hour Sleep-Wake Disorder (N24HSWD) in Blind Individuals With no Light Perception

Completed
NCT01163032Phase 3

Efficacy and Safety of Tasimelteon Compared With Placebo in Totally Blind Subjects With Non-24-Hour Sleep-Wake Disorder

Completed
NCT01430754Phase 3

Withdrawal Study to Demonstrate the Maintenance Effect in the Treatment of Non-24-Hour Sleep-Wake Disorder

Completed
NCT01402076Phase 1

A Study to Assess the Effect Tasimelteon on the Cytochrome P450 3A4 and 2C8 Enzymes in Healthy Subjects

Completed
NCT01540500Phase 1

Pharmacokinetics of Tasimelteon Alone and in Combination With CYP1A2 Inhibitor, Fluvoxamine

Completed
NCT01578057Phase 1

Evaluation of the Pharmacodynamic and Pharmacokinetic Interactions of Tasimelteon and Ethanol

Completed
NCT01271387Phase 1

Pharmacokinetics of Tasimelteon in Subjects With Mild or Moderate Hepatic Impairment

Completed
NCT01637636Phase 1

Pharmacokinetics of Tasimelteon Alone and in Combination With a CYP3A4 Inhibitor, Ketoconazole, or a CYP3A4 Inducer, Rifampin.

Completed
NCT01477619Phase 1

Effects of Smoking, Age and Body Size on Pharmacokinetics, Safety and Tolerability on Tasimelteon in Healthy Subjects

Completed
NCT01526746Phase 1

Pharmacokinetics of Tasimelteon in Subjects With Renal Impairment and Matched Control Subjects With Relatively Normal Renal Function

Completed

All 20 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
20