Success Metrics

Clinical Success Rate
100.0%

Based on 2 completed trials

Completion Rate
100%(2/2)
Active Trials
24(80%)
Results Posted
200%(4 trials)

Phase Distribution

Ph phase_1
11
37%
Ph phase_3
5
17%
Ph phase_2
13
43%

Phase Distribution

11

Early Stage

13

Mid Stage

5

Late Stage

Phase Distribution29 total trials
Phase 1Safety & dosage
11(37.9%)
Phase 2Efficacy & side effects
13(44.8%)
Phase 3Large-scale testing
5(17.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

66.7%

2 of 3 finished

Non-Completion Rate

33.3%

1 ended early

Currently Active

24

trials recruiting

Total Trials

30

all time

Status Distribution
Active(26)
Completed(2)
Terminated(1)
Other(1)

Detailed Status

Recruiting15
Active, not recruiting9
Completed2
Not yet recruiting2
Withdrawn1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
30
Active
24
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 111 (37.9%)
Phase 213 (44.8%)
Phase 35 (17.2%)

Trials by Status

completed27%
withdrawn13%
unknown13%
not_yet_recruiting27%
active_not_recruiting930%
recruiting1550%

Recent Activity

Clinical Trials (30)

Showing 20 of 30 trialsScroll for more
NCT07531095Phase 1

Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC)

Recruiting
NCT07242547Phase 2

Study of Tarlatamab as Maintenance Treatment After Chemo-radiotherapy for Limited Stage SCLC Patients

Recruiting
NCT07005128Phase 3

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

Recruiting
NCT06117774Phase 3

Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC)

Active Not Recruiting
NCT06814496Phase 1

Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors

Recruiting
NCT07328490Phase 1

Bispecific T-Cell Engager Tarlatamab and TROP2 Targeted Antibody Drug Conjugate Sacituzumab Govitecan in Previously Treated Extensive-Stage Small Cell Lung Cancer and Extrapulmonary Neuroendocrine Cancer

Withdrawn
NCT07402343Phase 2

Tarlatamab for SCLC Brain Metastases

Not Yet Recruiting
NCT06898957Phase 1

Study of Tarlatamab in Combination With YL201 With or Without Anti-programmed Death Ligand 1 (PD-L1) in Participants With Extensive Stage (ES) Small Cell Lung Cancer (SCLC)

Active Not Recruiting
NCT07243470Phase 1

Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors

Recruiting
NCT07203053Phase 2

A Trial of Tarlatamab in Patients With Pretreated Extensive-stage Small Cell Lung Cancer (ES-SCLC) and ECOG PS 2

Recruiting
NCT07111507Phase 2

A Study of Tarlatamab for People With Prostate Cancer

Recruiting
NCT06502977Phase 2

Study Evaluating Tarlatamab in Chinese Participants With Advanced Small Cell Lung Cancer After Two or More Prior Lines of Treatment

Active Not Recruiting
NCT06893783Phase 2

Efficacy and Safety Evaluation of Tarlatamab in Advanced Extrapulmonary Neuroendocrine Carcinoma Patients

Recruiting
NCT07037758Phase 1

A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

Recruiting
NCT05361395Phase 1

First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Active Not Recruiting
NCT06745323Phase 2

A Phase 2, Open-label, Randomized, Multicenter Study of Tarlatamab Dosing Regimens in Subjects With SCLC

Active Not Recruiting
NCT07423585Phase 2

Tarlatamab for the Treatment of Extensive Stage Small-cell Lung Cancer

Recruiting
NCT06937905Phase 3

Tarlatamab vs Standard of Care Chemotherapy in Patients With Pre-treated Advanced, Pulmonary or Gastroenteropancreatic Poorly Differentiated Neuroendocrine Carcinomas (NECs)

Recruiting
NCT07061080Phase 2

Refractory Advanced diGestive Neuroendocrine Carcinomas Treated With tARlatamab

Recruiting
NCT05740566Phase 3

Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
30