Success Metrics

Clinical Success Rate
50.0%

Based on 1 completed trials

Completion Rate
50%(1/2)
Active Trials
7(70%)
Results Posted
100%(1 trials)
Terminated
1(10%)

Phase Distribution

Ph early_phase_1
1
10%
Ph phase_1
5
50%
Ph phase_2
4
40%

Phase Distribution

6

Early Stage

4

Mid Stage

0

Late Stage

Phase Distribution10 total trials
Early Phase 1First-in-human
1(10.0%)
Phase 1Safety & dosage
5(50.0%)
Phase 2Efficacy & side effects
4(40.0%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

50.0%

1 of 2 finished

Non-Completion Rate

50.0%

1 ended early

Currently Active

7

trials recruiting

Total Trials

10

all time

Status Distribution
Active(8)
Completed(1)
Terminated(1)

Detailed Status

Recruiting7
Terminated1
Not yet recruiting1
Completed1

Development Timeline

Analytics

Development Status

Total Trials
10
Active
7
Success Rate
50.0%
Most Advanced
Phase 2

Trials by Phase

Early Phase 11 (10.0%)
Phase 15 (50.0%)
Phase 24 (40.0%)

Trials by Status

terminated110%
recruiting770%
not_yet_recruiting110%
completed110%

Recent Activity

Clinical Trials (10)

Showing 10 of 10 trials
NCT06414681Early Phase 1

Combination of Tagraxofusp With Pacritinib in Patients With Intermediate-1 or Higher Myelofibrosis, Who Have Had Prior Therapy With the Approved JAK Inhibitors or in Which Therapy With the Approved JAK Inhibitors is Not Appropriate, Contraindicated or Declined

Recruiting
NCT06561152Phase 1

Tagraxofusp and Low-Intensity Chemotherapy for CD123-Positive Relapsed or Refractory AML

Recruiting
NCT05442216Phase 2

Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents

Recruiting
NCT06456463Phase 2

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

Recruiting
NCT07148180Phase 1

A Multi-Site Break Through Cancer Trial: Targeting Measurable Residual Disease in Patients With Acute Myeloid Leukemia: A Phase 1/2 Study of Tagraxofusp, Azacitidine, and Venetoclax

Recruiting
NCT07007052Phase 2

Phase II Study Evaluating the Efficacy and Safety of the Combination of Tagraxofusp and Venetoclax in Treatment-naive Blastic Plasmacytoid Dendritic Cell Neoplasm Patients

Not Yet Recruiting
NCT05233618Phase 1

Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MDS, MF and CMML (HSCT 002)

Recruiting
NCT04342962Phase 2

Tagraxofusp in Patients With CD123+ or With BPDCN-IPh-like Acute Myeloid Leukemia

Terminated
NCT05476770Phase 1

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

Recruiting
NCT02113982Phase 1

Tagraxofusp in Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm or Acute Myeloid Leukemia

Completed

All 10 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
10