Success Metrics

Clinical Success Rate
93.8%

Based on 15 completed trials

Completion Rate
94%(15/16)
Active Trials
0(0%)
Results Posted
47%(7 trials)
Terminated
1(6%)

Phase Distribution

Ph not_applicable
2
11%
Ph phase_3
3
17%
Ph phase_1
3
17%
Ph phase_4
3
17%
Ph phase_2
4
22%

Phase Distribution

3

Early Stage

4

Mid Stage

6

Late Stage

Phase Distribution15 total trials
Phase 1Safety & dosage
3(20.0%)
Phase 2Efficacy & side effects
4(26.7%)
Phase 3Large-scale testing
3(20.0%)
Phase 4Post-market surveillance
3(20.0%)
N/ANon-phased studies
2(13.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

88.2%

15 of 17 finished

Non-Completion Rate

11.8%

2 ended early

Currently Active

0

trials recruiting

Total Trials

18

all time

Status Distribution
Completed(15)
Terminated(2)
Other(1)

Detailed Status

Completed15
unknown1
Terminated1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
18
Active
0
Success Rate
93.8%
Most Advanced
Phase 4

Trials by Phase

Phase 13 (20.0%)
Phase 24 (26.7%)
Phase 33 (20.0%)
Phase 43 (20.0%)
N/A2 (13.3%)

Trials by Status

unknown16%
completed1583%
terminated16%
withdrawn16%

Recent Activity

Clinical Trials (18)

Showing 18 of 18 trials
NCT00131885Phase 4

Effects of St. John's Wort on the Oral Contraceptive Hormone Levonorgestrel

Completed
NCT05477472

Low Dose St John's Wort for Depression

Completed
NCT00110136Phase 2

St. John's Wort in Relieving Hot Flashes in Postmenopausal Women With Non-Metastatic Breast Cancer

Terminated
NCT00048815Not Applicable

Drug Therapy to Treat Minor Depression

Completed
NCT02840331Phase 3

Pilot Study on Intra-abdominal Photodynamic Diagnosis in Peritoneal Carcinosis

Unknown
NCT01330589Not Applicable

Pharmacodynamic Study on Efficacy of Clopidogrel With St. John's Wort

Withdrawn
NCT01258504

Influence of CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Bosentan

Completed
NCT01311362

Influence of Cytochrome CYP3A4-induction by St. John's Wort on the Steady State Pharmacokinetics of Ambrisentan

Completed
NCT01921881Phase 1

Does the Natural Medicinal Plant St John's Wort Affect the Glucose Tolerance in Healthy Individuals

Completed
NCT01726764Phase 1

Interaction Between St John's Wort and Metformin?

Completed
NCT01663922Phase 1

Boceprevir and Ucalm (St John&Apos;s Wort)

Completed
NCT00005805Phase 3

St. John's Wort in Relieving Fatigue in Patients Undergoing Chemotherapy or Hormone Therapy for Cancer

Completed
NCT00587860Phase 2

A Placebo-Controlled Trial of St. John's Wort for Irritable Bowel Syndrome

Completed
NCT00351117Phase 3

St. John's Wort in the Treatment of Raynaud's Phenomenon

Completed
NCT00006395Phase 4

Drug Interaction Study of Tegretol (Carbamazepine) and St. John's Wort in Normal Volunteers

Completed
NCT00027014Phase 4

Herb-Opioid Interactions

Completed
NCT00035412Phase 2

St. John's Wort Versus Placebo in Social Phobia

Completed
NCT00035438Phase 2

St. John's Wort Vs. Placebo in Obsessive-Compulsive Disorder.

Completed

All 18 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
18