Success Metrics

Clinical Success Rate

93.1%

Based on 81 completed trials

Completion Rate

93%(81/87)

Active Trials

18(12%)

Results Posted

41%(33 trials)

Terminated

6(4%)

Phase Distribution

Ph early_phase_1

Ph not_applicable

14%

Ph phase_2

25%

Ph phase_3

13%

Ph phase_1

10%

Ph phase_4

34%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution143 total trials

Early Phase 1First-in-human

4(2.8%)

Phase 1Safety & dosage

14(9.8%)

Phase 2Efficacy & side effects

36(25.2%)

Phase 3Large-scale testing

19(13.3%)

Phase 4Post-market surveillance

49(34.3%)

N/ANon-phased studies

21(14.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

85.3%

81 of 95 finished

Non-Completion Rate

14.7%

14 ended early

Currently Active

trials recruiting

Total Trials

146

all time

Status Distribution

Active(23)

Completed(81)

Terminated(14)

Other(28)

Detailed Status

Completed81

unknown26

Recruiting15

Withdrawn8

Terminated6

Not yet recruiting4

Development Timeline

Analytics

Development Status

Total Trials

146

Active

Success Rate

93.1%

Most Advanced

Phase 4

Trials by Phase

Early Phase 14 (2.8%)

Phase 114 (9.8%)

Phase 236 (25.2%)

Phase 319 (13.3%)

Phase 449 (34.3%)

N/A21 (14.7%)

Trials by Status

unknown2618%

enrolling_by_invitation11%

active_not_recruiting32%

not_yet_recruiting43%

suspended21%

terminated64%

completed8155%

recruiting1510%

withdrawn85%

Recent Activity

18 active trials

Showing 5 of 146

completedphase_4

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1

NCT06004830

completedphase_2

Spironolactone Improved Children With Gene Mutations Related to NCOR

NCT06678685

View all 146 trials

Clinical Trials (146)

Showing 20 of 146 trialsScroll for more

NCT03344159Phase 4

Spironolactone Therapy in Chronic Stable Right HF Trial

Completed

NCT01712620Phase 2

Spironolactone for Pulmonary Arterial Hypertension

Recruiting

NCT05807139Phase 1

Spironolactone in Alcohol Use Disorder (SAUD)

Recruiting

NCT06004830Phase 2

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1

Active Not Recruiting

NCT06678685Phase 2

Spironolactone Improved Children With Gene Mutations Related to NCOR

Completed

NCT07483177Phase 1

HEART: Pilot Randomized Controlled Trial

Not Yet Recruiting

NCT04582383Phase 4

Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne

Active Not Recruiting

NCT03593317Phase 2

Blockade of the Renin-angiotensin-aldosterone System in Patients With ARVD

Recruiting

NCT07328230Not Applicable

Superselective Adrenal Arterial Embolization Versus Oral Spironolactone for Treatment of Idiopathic Hyperaldosteronism

Recruiting

NCT03429946Phase 4

Hypoglycemia and Autonomic Nervous System Function-B

Completed

NCT05561361

The Effect of SAAE on Vascular Endothelial Function in PA Patients

Recruiting

NCT04522739Phase 4

Spironolactone Safety in African Americans With Mild Cognitive Impairment and Early Dementia

Completed

NCT05754684Phase 2

Quadruple Immunotherapy for Neuroblastoma

Recruiting

NCT01552044Phase 1

Effect of Spironolactone in Treating Chronic Non-resolutive Central Serous Chorioretinitis

Completed

NCT07137364

Efficacy of Spironolactone Combined With Antihypertensive Drugs in Patients With Primary Aldosteronism

Recruiting

NCT03068910Early Phase 1

Hyperandrogenemia and Altered Day-night LH Pulse Patterns

Recruiting

NCT04723862Early Phase 1

Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?

Recruiting

NCT04676646Phase 4

Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone

Completed

NCT07020104Not Applicable

The Role of Skin Sodium Accumulation in Chronic Kidney Disease

Recruiting

NCT04901975Phase 1

Fibrosis and the Fontan

Recruiting

Drug Details

Intervention Type: DRUG
Total Trials: 146