Success Metrics

Clinical Success Rate
70.0%

Based on 14 completed trials

Completion Rate
70%(14/20)
Active Trials
3(13%)
Results Posted
121%(17 trials)
Terminated
6(26%)

Phase Distribution

Ph phase_3
3
13%
Ph phase_4
1
4%
Ph phase_1
3
13%
Ph phase_2
15
65%

Phase Distribution

3

Early Stage

15

Mid Stage

4

Late Stage

Phase Distribution22 total trials
Phase 1Safety & dosage
3(13.6%)
Phase 2Efficacy & side effects
15(68.2%)
Phase 3Large-scale testing
3(13.6%)
Phase 4Post-market surveillance
1(4.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

70.0%

14 of 20 finished

Non-Completion Rate

30.0%

6 ended early

Currently Active

3

trials recruiting

Total Trials

23

all time

Status Distribution
Active(3)
Completed(14)
Terminated(6)

Detailed Status

Completed14
Terminated6
Active, not recruiting2
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
23
Active
3
Success Rate
70.0%
Most Advanced
Phase 4

Trials by Phase

Phase 13 (13.6%)
Phase 215 (68.2%)
Phase 33 (13.6%)
Phase 41 (4.5%)

Trials by Status

completed1461%
active_not_recruiting29%
terminated626%
recruiting14%

Recent Activity

Clinical Trials (23)

Showing 20 of 23 trialsScroll for more
NCT06624670Phase 3

A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyoderma Gangrenosum

Recruiting
NCT06013969Phase 4

A Study to Test Whether Spesolimab Helps People With Generalized Pustular Psoriasis (GPP) Who Need Treatment for Repeated Flares

Active Not Recruiting
NCT03886246Phase 2

Effisayil™ ON: A Study to Test Long-term Treatment With Spesolimab in People With Generalized Pustular Psoriasis Who Took Part in a Previous Study

Active Not Recruiting
NCT06092216Phase 2

Spesolimab in Pyoderma Gangrenosum

Terminated
NCT06241573Phase 2

A Study to Test Long-term Treatment With Spesolimab in People With a Skin Condition Disease Called Hidradenitis Suppurativa (HS) Who Took Part in a Previous Study With Spesolimab

Terminated
NCT04493424Phase 2

A Study to Test Long-term Treatment With Spesolimab in People With Palmoplantar Pustulosis (PPP) Who Took Part in Previous Studies With Spesolimab

Terminated
NCT05670821

PMS of Spesolimab I.V. in GPP Patients With Acute Symptoms

Completed
NCT04399837Phase 2

A Study to Test Whether BI 655130 (Spesolimab) Prevents Flare-ups in Patients With Generalized Pustular Psoriasis

Completed
NCT05239039Phase 3

An Expanded Access Program in China to Provide Spesolimab to People With a Flare-up in Generalized Pustular Psoriasis Who Have no Other Treatment Options

Completed
NCT03648541Phase 2

BI 655130 Long-term Treatment in Patients With moderate-to Severe Ulcerative Colitis

Completed
NCT03100864Phase 2

This Study Tests How BI 655130 Works in Patients With Active Ulcerative Colitis. The Study Also Tests How Well BI 655130 is Tolerated and Whether it Helps the Patients

Completed
NCT03782792Phase 2

Effisayil™ 1: A Study to Test Spesolimab (BI 655130) in Patients With a Flare-up of a Skin Disease Called Generalized Pustular Psoriasis

Completed
NCT04015518Phase 2

A Study to Test How Effective and Safe Different Doses of BI 655130 Are in Patients With a Moderate to Severe Form of the Skin Disease Palmoplantar Pustulosis

Completed
NCT03482635Phase 2

BI655130 (SPESOLIMAB) Induction Treatment in Patients With Moderate-to-severe Ulcerative Colitis

Completed
NCT03123120Phase 2

A Study in Patients With Mild or Moderate Ulcerative Colitis Who Take a TNF Inhibitor. The Study Investigates Whether Bowel Inflammation Improves When Patients Take BI 655130 in Addition to Their Current Therapy

Completed
NCT03752970Phase 2

A Study Testing How BI 655130 Works in Patients With Fistulizing Crohn's Disease

Completed
NCT06520514Phase 1

A Study to Test How Well Healthy People Tolerate Spesolimab When Given in 2 Different Ways

Completed
NCT05200247Phase 3

An Expanded Access Trial in Japan to Provide Spesolimab to People With a Flare-up in Generalized Pustular Psoriasis Who Have no Other Treatment Options

Completed
NCT04086121Phase 2

A Study to Test the Long-term Safety of BI 655130 in Patients With Atopic Eczema Who Took Part in Study 1368-0032

Terminated
NCT05013385Phase 2

A Study to Test Whether Spesolimab Helps People With Crohn's Disease Who Have Symptoms of Bowel Obstruction

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
23