Success Metrics

Clinical Success Rate
38.5%

Based on 5 completed trials

Completion Rate
38%(5/13)
Active Trials
2(11%)
Results Posted
160%(8 trials)
Terminated
8(44%)

Phase Distribution

Ph phase_3
1
6%
Ph early_phase_1
1
6%
Ph phase_1
8
44%
Ph phase_2
8
44%

Phase Distribution

9

Early Stage

8

Mid Stage

1

Late Stage

Phase Distribution18 total trials
Early Phase 1First-in-human
1(5.6%)
Phase 1Safety & dosage
8(44.4%)
Phase 2Efficacy & side effects
8(44.4%)
Phase 3Large-scale testing
1(5.6%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

35.7%

5 of 14 finished

Non-Completion Rate

64.3%

9 ended early

Currently Active

2

trials recruiting

Total Trials

18

all time

Status Distribution
Active(2)
Completed(5)
Terminated(9)
Other(2)

Detailed Status

Terminated8
Completed5
Active, not recruiting2
Withdrawn1
Suspended1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
18
Active
2
Success Rate
38.5%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (5.6%)
Phase 18 (44.4%)
Phase 28 (44.4%)
Phase 31 (5.6%)

Trials by Status

withdrawn16%
terminated844%
active_not_recruiting211%
completed528%
suspended16%
unknown16%

Recent Activity

Clinical Trials (18)

Showing 18 of 18 trials
NCT04028245Early Phase 1

A Study of Combination Spartalizumab and Canakinumab in Patients With Localized Clear Cell Renal Cell Carcinoma

Completed
NCT05201066Phase 2

Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab.

Active Not Recruiting
NCT04294160Phase 1

A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer

Terminated
NCT04390763Phase 2

Study of Efficacy and Safety of NIS793 (With and Without Spartalizumab) in Combination With SOC Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC)

Terminated
NCT04000529Phase 1

Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies

Terminated
NCT02967692Phase 3

A Study of the Anti-PD1 Antibody PDR001, in Combination With Dabrafenib and Trametinib in Advanced Melanoma

Terminated
NCT04191421Phase 1

Siltuximab and Spartalizumab in Patients With Metastatic Pancreatic Cancer

Completed
NCT03742349Phase 1

Study of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cancer (TNBC).

Terminated
NCT04261439Phase 1

A Phase I/Ib Study of NIZ985 Alone and in Combination With Spartalizumab

Terminated
NCT04802876Phase 2

Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors

Active Not Recruiting
NCT04310397Phase 2

Dabrafenib, Trametinib, and Spartalizumab for the Treatment of BRAF V600E or V600K Mutation Positive Stage IIIB/C/D Melanoma

Terminated
NCT04323436Phase 2

Study of Capmatinib and Spartalizumab/Placebo in Advanced NSCLC Patients With MET Exon 14 Skipping Mutations

Terminated
NCT02795429Phase 1

Phase Ib/II Study of INC280 + PDR001 or PDR001 Single Agent in Advanced HCC

Completed
NCT05135845Phase 2

Combination of Capmatinib + Spartalizumab in Advanced Oesogastric Adenocarcinoma

Suspended
NCT04213404Phase 1

Ribociclib and Spartalizumab in R/M HNSCC

Unknown
NCT02605967Phase 2

Safety and Efficacy Study of PDR001 in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma

Completed
NCT03647488Phase 2

Study of Capmatinib and Spartalizumab Combination Therapy vs Docetaxel in Non-small Cell Lung Cancer

Completed
NCT04283526Phase 1

Study of Select Combinations in Adults With Myelofibrosis

Withdrawn

All 18 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
18