Success Metrics

Clinical Success Rate
88.9%

Based on 16 completed trials

Completion Rate
89%(16/18)
Active Trials
0(0%)
Results Posted
25%(4 trials)
Terminated
2(11%)

Phase Distribution

Ph phase_1
11
61%
Ph phase_2
1
6%
Ph phase_3
6
33%

Phase Distribution

11

Early Stage

1

Mid Stage

6

Late Stage

Phase Distribution18 total trials
Phase 1Safety & dosage
11(61.1%)
Phase 2Efficacy & side effects
1(5.6%)
Phase 3Large-scale testing
6(33.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

88.9%

16 of 18 finished

Non-Completion Rate

11.1%

2 ended early

Currently Active

0

trials recruiting

Total Trials

18

all time

Status Distribution
Completed(16)
Terminated(2)

Detailed Status

Completed16
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
18
Active
0
Success Rate
88.9%
Most Advanced
Phase 3

Trials by Phase

Phase 111 (61.1%)
Phase 21 (5.6%)
Phase 36 (33.3%)

Trials by Status

completed1689%
terminated211%

Recent Activity

Clinical Trials (18)

Showing 18 of 18 trials
NCT03211195Phase 1

Sotagliflozin Bioequivalence Study

Completed
NCT03802487Phase 1

Study To Determine Bioavailability of Sotagliflozin in Healthy Male and Female Subjects

Completed
NCT03760965Phase 3

Efficacy and Safety of Sotagliflozin Versus Placebo in Chinese Patients With Type 2 Diabetes Mellitus Not Adequately Controlled by Diet and Exercise

Terminated
NCT03414723Phase 1

A Drug-Drug Interaction Study Between Sotagliflozin and Ramipril

Completed
NCT03776227Phase 1

A Bioequivalence Study Testing Two Formulations of Sotagliflozin in Healthy Male and Female Subjects Under Fasted Conditions

Completed
NCT03070678Phase 1

Interaction Study to Evaluate the Effects of Mefenamic Acid on the Pharmacokinetics and Pharmacodynamics of Sotagliflozin in Healthy Male and Female Subjects

Completed
NCT03063580Phase 1

Effect of Rifampicin on the Pharmacokinetics and Pharmacodynamics of Sotagliflozin

Completed
NCT03909451Phase 1

Sotagliflozin Multiple-dose Study in Healthy Chinese Subjects

Completed
NCT03174548Phase 1

A Study to Evaluate the Effect of Food on the Pharmacokinetics of Sotagliflozin and to Explore the Relative Bioavailability in Healthy Subjects

Completed
NCT02940379Phase 1

A Drug to Drug Interaction Study of Sotagliflozin With Midazolam and Metoprolol

Completed
NCT03462069Phase 2

Comparison of Pharmacodynamic Effects of Sotagliflozin and Empagliflozin in T2DM Patients With Mild to Moderate Hypertension

Completed
NCT03387657Phase 1

A Drug to Drug Interaction Study of Sotagliflozin With Hydrochlorothiazide

Completed
NCT03761134Phase 3

Efficacy and Safety of Sotagliflozin Versus Placebo in Chinese Patients With Type 2 Diabetes Mellitus Not Adequately Controlled by Metformin With or Without Sulfonylurea

Terminated
NCT03310944Phase 1

Comparison of Sotagliflozin Prototype Tablets With Reference Tablet in Healthy Subjects

Completed
NCT02926937Phase 3

Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus Not Currently Treated With Antidiabetic Therapy

Completed
NCT03066830Phase 3

Efficacy and Safety of Sotagliflozin Versus Placebo in Participants With Type 2 Diabetes Mellitus on Background of Sulfonylurea Alone or With Metformin

Completed
NCT03332771Phase 3

Efficacy and Safety of Sotagliflozin Versus Glimepiride and Placebo in Participants With Type 2 Diabetes Mellitus That Are Taking Metformin Monotherapy

Completed
NCT02926950Phase 3

Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus on Background of Metformin

Completed

All 18 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
18