Success Metrics

Clinical Success Rate
91.8%

Based on 45 completed trials

Completion Rate
92%(45/49)
Active Trials
1(2%)
Results Posted
49%(22 trials)
Terminated
4(8%)

Phase Distribution

Ph phase_3
13
25%
Ph phase_2
11
22%
Ph phase_1
7
14%

Phase Distribution

7

Early Stage

11

Mid Stage

13

Late Stage

Phase Distribution31 total trials
Phase 1Safety & dosage
7(22.6%)
Phase 2Efficacy & side effects
11(35.5%)
Phase 3Large-scale testing
13(41.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

90.0%

45 of 50 finished

Non-Completion Rate

10.0%

5 ended early

Currently Active

1

trials recruiting

Total Trials

51

all time

Status Distribution
Active(1)
Completed(45)
Terminated(5)

Detailed Status

Completed45
Terminated4
Active, not recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
51
Active
1
Success Rate
91.8%
Most Advanced
Phase 3

Trials by Phase

Phase 17 (22.6%)
Phase 211 (35.5%)
Phase 313 (41.9%)

Trials by Status

active_not_recruiting12%
terminated48%
completed4588%
withdrawn12%

Recent Activity

Clinical Trials (51)

Showing 20 of 51 trialsScroll for more
NCT02185560

Prospective, Non-interventional, Post-authorization Safety Study That Includes All Patients Diagnosed as Unresectable Differentiated Thyroid Carcinoma and Treated With Sorafenib

Active Not Recruiting
NCT05594147

An Observational Study, Called ROCURS, to Learn About COVID-19 Related Outcomes in People With Cancer Who Are Treated With Tyrosine Kinase Inhibitors (TKIs) Including Regorafenib or Sorafenib

Completed
NCT02303444

An Observational Study in Differentiated Thyroid Cancer Which is Radioactive Iodine (RAI) Refractory to Assess the Use of Multikinase Inhibitors

Completed
NCT00625378Phase 3

Sorafenib Long Term Extension Program

Completed
NCT03644511

Use of Sorafenib and/or Regorafenib in Liver Cancer (Hepatocellular Carcinoma) Subsequent to Another Systemic First-line Treatment

Terminated
NCT01195649

Advanced Renal Cell Carcinoma, With Failure or Unsuitable on Prior Interferon-alpha or Interleukin-2 Based Therapy

Terminated
NCT00901901Phase 3

Nexavar-Tarceva Combination Therapy for First Line Treatment of Patients Diagnosed With Hepatocellular Carcinoma

Completed
NCT01234337Phase 3

Phase III Trial Comparing Capecitabine in Combination With Sorafenib or Placebo in the Treatment of Locally Advanced or Metastatic HER2-Negative Breast Cancer

Completed
NCT01933945

Outcomes of HCC (Hepatocellular Carcinoma) Patients Treated With TACE (Transarterial Chemoembolization) and Early, Not Early or Not at All Followed by Sorafenib

Completed
NCT00984282Phase 3

Nexavar® Versus Placebo in Locally Advanced/Metastatic RAI-Refractory Differentiated Thyroid Cancer

Completed
NCT01411423

Nexavar Post-marketing Surveillance for Renal Cell Carcinoma in Japan

Completed
NCT01412671

Nexavar Post-marketing Surveillance for RCC in Japan: Early Access Program

Completed
NCT01839630

Sorafenib Concomitantly Used With TACE (Transarterial Chemoembolization) in uHCC (Unresectable Hepatocellular Carcinoma) Patients in China

Completed
NCT01728948

Sorafenib in Elderly mRCC

Completed
NCT01751763

Sorafenib for Residue Disease After Resection With Curative Intent

Completed
NCT00855218Phase 2

A Phase II Randomized, Double-blind, Placebo-controlled Study of Sorafenib or Placebo in Combination With Transarterial Chemoembolization (TACE) Performed With DC Bead and Doxorubicin for Intermediate Stage Hepatocellular Carcinoma (HCC).

Completed
NCT01557127

Nexavar Dosing in Renal Cancer Patients in "Real-life" Setting

Completed
NCT00812175

Global Investigation of Therapeutic Decisions in Hepatocellular Carcinoma and of Its Treatment With Sorafenib

Completed
NCT01539681

Sorafenib in Hepatocellular Carcinoma Clinical Practice in Italy

Completed
NCT00618982Phase 2

Sorafenib Dose Escalation in Renal Cell Carcinoma

Completed

Drug Details

Intervention Type
DRUG
Total Trials
51