Success Metrics

Clinical Success Rate
93.8%

Based on 61 completed trials

Completion Rate
94%(61/65)
Active Trials
0(0%)
Results Posted
66%(40 trials)
Terminated
4(5%)

Phase Distribution

Ph phase_2
32
42%
Ph not_applicable
2
3%
Ph phase_3
22
29%
Ph phase_4
11
14%
Ph phase_1
2
3%

Phase Distribution

2

Early Stage

32

Mid Stage

33

Late Stage

Phase Distribution69 total trials
Phase 1Safety & dosage
2(2.9%)
Phase 2Efficacy & side effects
32(46.4%)
Phase 3Large-scale testing
22(31.9%)
Phase 4Post-market surveillance
11(15.9%)
N/ANon-phased studies
2(2.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

88.4%

61 of 69 finished

Non-Completion Rate

11.6%

8 ended early

Currently Active

0

trials recruiting

Total Trials

77

all time

Status Distribution
Completed(61)
Terminated(8)
Other(8)

Detailed Status

Completed61
unknown8
Terminated4
Withdrawn4

Development Timeline

Analytics

Development Status

Total Trials
77
Active
0
Success Rate
93.8%
Most Advanced
Phase 4

Trials by Phase

Phase 12 (2.9%)
Phase 232 (46.4%)
Phase 322 (31.9%)
Phase 411 (15.9%)
N/A2 (2.9%)

Trials by Status

completed6179%
terminated45%
withdrawn45%
unknown810%

Recent Activity

Clinical Trials (77)

Showing 20 of 77 trialsScroll for more
NCT02771405Phase 3

Impact of Interferon Free Regimens in Patients With Chronic HCV and Successfully Treated HCC

Completed
NCT02262728Phase 2

An Efficacy, Safety and Pharmacokinetics Study of Simeprevir, Daclatasvir and Sofosbuvir in Participants With Chronic Hepatitis C Virus Genotype 1 or 4 Infection and Decompensated Liver Disease

Completed
NCT05717400Phase 4

Improving Response to Immunotherapy in Patients With Advanced Hepatocellular Carcinoma and Chronic Hepatitis C Virus Infection With Direct-Acting Antiviral Therapy

Terminated
NCT02292706

A Registry for Participants With Cirrhosis Who Achieve a Sustained Virologic Response Following Treatment With a Sofosbuvir-Based Regimen Without Interferon for Chronic Hepatitis C Infection

Terminated
NCT02992457Phase 4

Safety and Efficacy of Sofosbuvir-Based Regimens in the Treatment of Egyptian Patients With Hepatitis C Infection

Completed
NCT02596880Phase 3

Sofosbuvir, Daclatasvir, Ribavirin for Hepatitis C Virus (HCV) Cirrhotics

Completed
NCT04246723Phase 2

Efficacy and Safety of All-Oral Combination of Narlaprevir/Ritonavir and Sofosbuvir in Treatment-naïve Patients With Chronic Hepatitis C Genotype 1

Completed
NCT02333292

Efficacy and Safety of Therapy Against HCV Based on Direct-acting Antivirals in Real-life Conditions

Completed
NCT02939989Phase 3

Efficacy and Safety of Glecaprevir (ABT-493)/Pibrentasvir (ABT 530) (GLE/PIB) in Combination With Sofosbuvir and Ribavirin in Participants With Hepatitis C Virus Who Did Not Respond to Treatment in a Previous AbbVie Clinical Study

Completed
NCT03706898Phase 1

Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact of Food Intake and Drug-Drug Interactions With Other Antiviral Drugs

Completed
NCT02907996

Evaluate the Safety and Effectiveness of Sovaldi in Participants With Chronic Hepatitis C Virus (HCV) Infection in Korea

Completed
NCT02640157Phase 3

A Study Comparing Efficacy and Safety of ABT-493/ABT-530 to Sofosbuvir Dosed With Daclatasvir in Adults With HCV Genotype 3 Infection

Completed
NCT02292719Phase 2

A Study to Evaluate the Safety and Efficacy of Ombitasvir/ABT-450/Ritonavir With Sofosbuvir With or Without Ribavirin in Adults With Chronic Hepatitis C Virus Infection

Completed
NCT03480932Phase 2

Role of Pegylated Interferon in Combination With DAAs to Cure Hepatitis C As Soon As Possible - Hepatitis C [ASAP-C]

Completed
NCT03487848Phase 2

Evaluation of Daclatasvir (DCV) in Combination With Sofosbuvir (SOF) in Children With Chronic Hepatitis C (CHC) Infection

Terminated
NCT02541409Phase 2

Directly Observed Therapy for HCV in Chennai, India

Completed
NCT03883698Phase 3

Safety of Sofosbuvir in People With Advanced Kidney Failure

Completed
NCT02133131Phase 2

Efficacy and Safety of Grazoprevir (MK-5172), Elbasvir (MK-8742), and Sofosbuvir for Chronic Infection With Hepatitis C Virus Genotypes 1 and 3 (MK-5172-074)

Completed
NCT04664894

Direct Acting Anti-Viral's In Chronic HCV Patients

Completed
NCT04460443Phase 2

Sofosbuvir in Treatment of COVID 19

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
77