Success Metrics

Clinical Success Rate
70.0%

Based on 14 completed trials

Completion Rate
70%(14/20)
Active Trials
4(14%)
Results Posted
50%(7 trials)
Terminated
6(21%)

Phase Distribution

Ph phase_2
5
17%
Ph phase_4
2
7%
Ph phase_1
10
34%
Ph phase_3
1
3%
Ph not_applicable
4
14%
Ph early_phase_1
3
10%

Phase Distribution

13

Early Stage

5

Mid Stage

3

Late Stage

Phase Distribution25 total trials
Early Phase 1First-in-human
3(12.0%)
Phase 1Safety & dosage
10(40.0%)
Phase 2Efficacy & side effects
5(20.0%)
Phase 3Large-scale testing
1(4.0%)
Phase 4Post-market surveillance
2(8.0%)
N/ANon-phased studies
4(16.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

63.6%

14 of 22 finished

Non-Completion Rate

36.4%

8 ended early

Currently Active

4

trials recruiting

Total Trials

29

all time

Status Distribution
Active(4)
Completed(14)
Terminated(8)
Other(3)

Detailed Status

Completed14
Terminated6
unknown3
Active, not recruiting2
Recruiting2
Withdrawn2

Development Timeline

Analytics

Development Status

Total Trials
29
Active
4
Success Rate
70.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (12.0%)
Phase 110 (40.0%)
Phase 25 (20.0%)
Phase 31 (4.0%)
Phase 42 (8.0%)
N/A4 (16.0%)

Trials by Status

terminated621%
unknown310%
active_not_recruiting27%
completed1448%
recruiting27%
withdrawn27%

Recent Activity

4 active trials
Showing 5 of 29
active_not_recruitingphase_1

Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in Obesity

NCT03318094
terminatedphase_1

HeartPhone Cancer Survivors Trial 2019

NCT03953326
terminatedphase_2

Sodium Nitroprusside in Early Course Schizophrenia

NCT04986072
active_not_recruiting

Estrogen and Microvascular Function

NCT06043310
recruitingnot_applicable

Hot Flashes and Neurovascular Function in Women

NCT05193968
View all 29 trials

Clinical Trials (29)

Showing 20 of 29 trialsScroll for more
NCT03318094Phase 1

Role of Sympathetic Vasoconstriction on Insulin-Mediated Microvascular Recruitment and Glucose Uptake in Obesity

Active Not Recruiting
NCT03953326Phase 1

HeartPhone Cancer Survivors Trial 2019

Terminated
NCT04986072Phase 2

Sodium Nitroprusside in Early Course Schizophrenia

Terminated
NCT06043310

Estrogen and Microvascular Function

Active Not Recruiting
NCT05193968Not Applicable

Hot Flashes and Neurovascular Function in Women

Recruiting
NCT05277922Phase 1

Effect of C21 on Forearm Blood Flow

Completed
NCT04001647Early Phase 1

Targeting ER Stress in Vascular Dysfunction

Terminated
NCT05525416Not Applicable

Sex Differences in Sympathetic Vascular Reactivity at High Altitude

Completed
NCT06443151

Role of Endothelial Function in SCI CVD Risk

Recruiting
NCT03679780Phase 1

The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction

Completed
NCT03446612Phase 2

Anemia Study in Chronic Kidney Disease (CKD) : Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat -Forearm Blood Flow (ASCEND-FBF)

Terminated
NCT04928183Not Applicable

The Impact of Carbon Monoxide and Altitude on Vascular Function

Completed
NCT03972683Early Phase 1

Role of Acetylcholine in Blood Flow Regulation in Healthy Adults: Effects of Age and Exercise Training

Withdrawn
NCT03738943Early Phase 1

Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults

Completed
NCT02767024Phase 4

Intravenous Vasodilator vs. Inotropic Therapy in Patients With Heart Failure

Withdrawn
NCT02164981Phase 2

A Proof of Concept Study of Intravenous Sodium Nitroprusside in Adults With Symptomatic Schizophrenia

Completed
NCT03680573Phase 1

The Effect of Antioxidants on Skin Blood Flow-BH4

Completed
NCT00166166Phase 2

Endothelial Hyperpolarization in Humans

Terminated
NCT00580905Phase 1

Role of Adenosine in the Release of VEGF and Cytokines

Terminated
NCT00152724

Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers

Completed

Drug Details

Intervention Type
DRUG
Total Trials
29