Success Metrics

Active Trials
15(79%)

Phase Distribution

Ph phase_3
8
42%
Ph phase_2
10
53%
Ph phase_1
1
5%

Phase Distribution

1

Early Stage

10

Mid Stage

8

Late Stage

Phase Distribution19 total trials
Phase 1Safety & dosage
1(5.3%)
Phase 2Efficacy & side effects
10(52.6%)
Phase 3Large-scale testing
8(42.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

0.0%

0 of 0 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

15

trials recruiting

Total Trials

19

all time

Status Distribution
Active(19)

Detailed Status

Active, not recruiting8
Recruiting7
Not yet recruiting4

Development Timeline

Analytics

Development Status

Total Trials
19
Active
15
Success Rate
N/A
Most Advanced
Phase 3

Trials by Phase

Phase 11 (5.3%)
Phase 210 (52.6%)
Phase 38 (42.1%)

Trials by Status

not_yet_recruiting421%
active_not_recruiting842%
recruiting737%

Recent Activity

Clinical Trials (19)

Showing 19 of 19 trials
NCT07545213Phase 2

Efficacy and Safety of SKB264 Plus Anlotinib in EGFR-TKI-Resistant Advanced NSCLC With Liver Metastasis

Not Yet Recruiting
NCT06448312Phase 3

A Study of SKB264 in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Active Not Recruiting
NCT07466927Phase 2

Study of Multi-mode Thermal Therapy Combined With Immunotherapy In Patients With HER2-negative Breast Cancer With Liver Metastases

Not Yet Recruiting
NCT05631262Phase 2

SKB264 Monotherapy in Selected Subjects With Advanced Solid Tumors

Active Not Recruiting
NCT06711900Phase 3

A Study of SKB264 in Combination With Pembrolizumab Versus Chemotherapy in Combination With Pembrolizumab as First-Line Treatment for PD-L1 Negative Patients With Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Recruiting
NCT05816252Phase 2

A Study of SKB264 (MK-2870; Sac-TMT) for the Treatment of Participants With Advanced or Metastatic Non-small Cell Lung Cancer (SKB264-II-04) (MK-2870-003)

Active Not Recruiting
NCT07371208Phase 2

Multicenter, Phase II Clinical Study of Sacituzumab Tirumotecan (Sac-TMT) in Combination With KL-A167 for Neoadjuvant Treatment of Triple-Negative Breast Cancer

Recruiting
NCT06279364Phase 3

A Study of SKB264 Versus Investigator's Choice Chemotherapy in Patients With Unresectable Recurrent or Metastatic Triple-Negative Breast Cancer

Recruiting
NCT07341100Phase 2

Study to Evaluate the Preliminary Efficacy of SKB264 and the Effect of Clarithromycin on the PK of SKB264 in OC

Not Yet Recruiting
NCT07071337Phase 3

A Study of SKB264 Versus Investigator's Choice of Chemotherapy in Subjects With Unresectable Locally Advanced, Relapsed, or Metastatic HR+/HER2- Breast Cancer Who Have Previously Failed Endocrine Therapy

Recruiting
NCT05347134Phase 3

SKB264 Injection vs Investigator Selected Regimens to Treat Locally Advanced, Recurrent or Metastatic Triple-negative Breast Cancer

Active Not Recruiting
NCT06081959Phase 3

Study of SKB264 for Locally Advanced, Recurrent or Metastatic HR+/HER2- Breast Cancer

Recruiting
NCT05870319Phase 3

A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients

Active Not Recruiting
NCT06670196Phase 3

A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutations, Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Recruiting
NCT05445908Phase 2

SKB264 +/- KL-A167 in Recurrent or Metastatic HER2-negative Breast Cancer

Active Not Recruiting
NCT05642780Phase 2

SKB264 in Combination With Pembrolizumab in Subjects With Selected Solid Tumors

Active Not Recruiting
NCT04152499Phase 1

Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01)

Active Not Recruiting
NCT06849492Phase 2

HIM Typing Guides the Treatment of Advanced First-Line Triple-Negative Breast Cancer

Not Yet Recruiting
NCT05351788Phase 2

SKB264 Combinatiton Therapy in Patients With Advanced or Metastatic Non-small Cell Lung Cancer.

Recruiting

All 19 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
19