Success Metrics

Clinical Success Rate
66.7%

Based on 6 completed trials

Completion Rate
67%(6/9)
Active Trials
8(33%)
Results Posted
33%(2 trials)
Terminated
3(13%)

Phase Distribution

Ph phase_4
7
29%
Ph not_applicable
2
8%
Ph early_phase_1
1
4%
Ph phase_1
2
8%
Ph phase_2
8
33%
Ph phase_3
4
17%

Phase Distribution

3

Early Stage

8

Mid Stage

11

Late Stage

Phase Distribution24 total trials
Early Phase 1First-in-human
1(4.2%)
Phase 1Safety & dosage
2(8.3%)
Phase 2Efficacy & side effects
8(33.3%)
Phase 3Large-scale testing
4(16.7%)
Phase 4Post-market surveillance
7(29.2%)
N/ANon-phased studies
2(8.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

66.7%

6 of 9 finished

Non-Completion Rate

33.3%

3 ended early

Currently Active

8

trials recruiting

Total Trials

24

all time

Status Distribution
Active(8)
Completed(6)
Terminated(3)
Other(7)

Detailed Status

unknown7
Completed6
Recruiting6
Terminated3
Active, not recruiting2

Development Timeline

Analytics

Development Status

Total Trials
24
Active
8
Success Rate
66.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (4.2%)
Phase 12 (8.3%)
Phase 28 (33.3%)
Phase 34 (16.7%)
Phase 47 (29.2%)
N/A2 (8.3%)

Trials by Status

active_not_recruiting28%
completed625%
terminated313%
unknown729%
recruiting625%

Recent Activity

Clinical Trials (24)

Showing 20 of 24 trialsScroll for more
NCT05586360Phase 2

T-reg Function Changes: a Novel Immune Regulatory Effect Underlying Benefit of Statin Use on Lethal Prostate Cancer

Recruiting
NCT04457089Early Phase 1

Statin Therapy to Reduce Progression in Women With Platinum Sensitive Ovarian Cancer

Completed
NCT03654053Phase 3

Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis

Active Not Recruiting
NCT04133792Phase 3

Effect of Simvastatin on the Prognosis of Primary Primary Sclerosing Cholangitis (PSC)

Active Not Recruiting
NCT03400826Phase 2

Effects of Simvastatin on Uterine Leiomyoma Size

Recruiting
NCT04021498Phase 3

Simvastatin in the Prevention of Recurrent Pancreatitis

Terminated
NCT04301271Phase 2

Simvastatin add-on Treatment to Standard Antidepressant Therapy in Patients With Comorbid Obesity and Major Depression

Completed
NCT04971577Phase 2

Efficacy of Simvastatin in Alcoholic Liver Fibrosis

Recruiting
NCT04638400Phase 4

Anti-inflammatory Effects of Simvastatin

Terminated
NCT05550415Phase 2

The Role of Simvastatin in the Epithelial-Mesenchymal Transition Process of Breast Cancer

Recruiting
NCT03131726Phase 3

Treatment of Graves´ophthalmopathy with Simvastatin (GO-S)

Recruiting
NCT06379958Phase 1

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Recruiting
NCT04507373Phase 4

7T Magnetic Resonance Spectroscopy and Skeletal Muscle Biopsy Findings in Statin Associated Adverse Muscle Events

Terminated
NCT05187715Not Applicable

To Study the Safety and Efficacy of Simvastatin in Patients With Hepatopulmonary Syndrome in Cirrhosis.

Unknown
NCT04049786Phase 4

Impact of Bariatric Surgery on Pharmacokinetic Study of Simvastatin and Carvedilol

Unknown
NCT02490527Not Applicable

Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise Capacity

Completed
NCT03599609Phase 1

Central Nervous System Vascular Changes in Adult Sickle Cell Disease and the Effect of Treatment With Simvastatin

Unknown
NCT04418089Phase 2

Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer

Completed
NCT04140201Phase 4

Effect of Lipid Lowering Agents on Diabetic Retinopathy and Cardiovascular Risk of Diabetic Patients

Unknown
NCT04183387Phase 2

Simvastatin in Uveitis

Completed

Drug Details

Intervention Type
DRUG
Total Trials
24