Success Metrics

Clinical Success Rate
90.2%

Based on 229 completed trials

Completion Rate
90%(229/254)
Active Trials
9(3%)
Results Posted
39%(90 trials)
Terminated
25(8%)

Phase Distribution

Ph early_phase_1
11
3%
Ph phase_1
74
23%
Ph phase_2
62
19%
Ph phase_3
70
22%
Ph phase_4
63
20%
Ph not_applicable
39
12%

Phase Distribution

85

Early Stage

62

Mid Stage

133

Late Stage

Phase Distribution319 total trials
Early Phase 1First-in-human
11(3.4%)
Phase 1Safety & dosage
74(23.2%)
Phase 2Efficacy & side effects
62(19.4%)
Phase 3Large-scale testing
70(21.9%)
Phase 4Post-market surveillance
63(19.7%)
N/ANon-phased studies
39(12.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

84.8%

229 of 270 finished

Non-Completion Rate

15.2%

41 ended early

Currently Active

9

trials recruiting

Total Trials

321

all time

Status Distribution
Active(11)
Completed(229)
Terminated(41)
Other(40)

Detailed Status

Completed229
unknown40
Terminated25
Withdrawn16
Recruiting6
Active, not recruiting3

Development Timeline

Analytics

Development Status

Total Trials
321
Active
9
Success Rate
90.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 111 (3.4%)
Phase 174 (23.2%)
Phase 262 (19.4%)
Phase 370 (21.9%)
Phase 463 (19.7%)
N/A39 (12.2%)

Trials by Status

completed22971%
recruiting62%
active_not_recruiting31%
not_yet_recruiting10%
withdrawn165%
enrolling_by_invitation10%
terminated258%
unknown4012%

Recent Activity

Clinical Trials (321)

Showing 20 of 321 trialsScroll for more
NCT02968810Phase 2

Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis

Active Not Recruiting
NCT05771675Early Phase 1

Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis

Recruiting
NCT04514029Early Phase 1

Neurotoxicity Prophylaxis With Intrathecal Dexamethasone and Simvastatin Post Axi-Cel

Active Not Recruiting
NCT00858637Phase 3

Efficacy and Safety Study of MCI-196 Versus Simvastatin for Dyslipidaemia in Chronic Kidney Disease (CKD) Subjects on Dialysis

Completed
NCT02675309Phase 1

A Study to Investigate the Effect of MT-8554 on the Pharmacokinetics of Simvastatin and Rosuvastatin in Healthy Subjects

Completed
NCT02197234Phase 1

Study to Assess the Effect of AZD9291 on the Blood Levels of Simvastatin in Patients With EGFRm+ NSCLC

Completed
NCT03889795Phase 1

Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors

Active Not Recruiting
NCT06948747Phase 1

A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of Erythromycin on AZD5004 in Healthy Participants

Completed
NCT07102979Not Applicable

Remedial Mechanism of Simvastatin and Ursodeoxycholic Acid in Liver Cirrhosis: Crosstalk of Bile Secretion, Gut Microbiome, and Host Immune Response

Enrolling By Invitation
NCT06858332

Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia

Recruiting
NCT03896217Phase 2

Simvastatin in Secondary Progressive Multiple Sclerosis

Completed
NCT07031778Early Phase 1

Topic Simvastatin for Bone Regeneration

Recruiting
NCT05464810Early Phase 1

Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer

Recruiting
NCT01602029Phase 2

Randomized Double Blind Placebo Control Study in Patients with Schizophrenia

Completed
NCT03387670Phase 3

Multiple Sclerosis-Simvastatin Trial 2

Completed
NCT00651391Phase 3

Effect of Ezetimibe Plus Simvastatin on Flow-Mediated Brachial Artery Vasoactivity in Subjects With Primary Hypercholesterolemia (Study P03336)

Terminated
NCT00166530Phase 4

EASEGO Study: Doubling of Atorvastatin/Simvastatin or INEGY in Patients With Hypercholesterolemia and Coronary Artery Disease(CAD)(0653A-089)

Completed
NCT00652717Phase 4

Study To Assess The Efficacy Of A Cholesterol Lowering Drug On Top Of Statins In Patients After Myocardial Infarction (MI)(0653A-150)

Completed
NCT00653835Phase 4

Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435)

Completed
NCT00650819Phase 3

Comparison of Ezetimibe Plus Simvastatin Versus Ezetimibe or Simvastatin Alone in Subjects With Primary Hypercholesterolemia (Study P03757)(COMPLETED)

Completed

Drug Details

Intervention Type
DRUG
Total Trials
321