Success Metrics

Clinical Success Rate
100.0%

Based on 2 completed trials

Completion Rate
100%(2/2)
Active Trials
25(56%)
Results Posted
0%(0 trials)

Phase Distribution

Ph not_applicable
1
2%
Ph phase_1
10
22%
Ph phase_2
25
56%
Ph phase_3
9
20%

Phase Distribution

10

Early Stage

25

Mid Stage

9

Late Stage

Phase Distribution45 total trials
Phase 1Safety & dosage
10(22.2%)
Phase 2Efficacy & side effects
25(55.6%)
Phase 3Large-scale testing
9(20.0%)
N/ANon-phased studies
1(2.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

2 of 2 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

25

trials recruiting

Total Trials

45

all time

Status Distribution
Active(42)
Completed(2)
Other(1)

Detailed Status

Recruiting20
Not yet recruiting17
Active, not recruiting5
Completed2
unknown1

Development Timeline

Analytics

Development Status

Total Trials
45
Active
25
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 110 (22.2%)
Phase 225 (55.6%)
Phase 39 (20.0%)
N/A1 (2.2%)

Trials by Status

not_yet_recruiting1738%
recruiting2044%
unknown12%
active_not_recruiting511%
completed24%

Recent Activity

Clinical Trials (45)

Showing 20 of 45 trialsScroll for more
NCT07560475Phase 2

Exploratory Study of SHR-A1811 Via Different Administration Routes in Patients

Not Yet Recruiting
NCT06828354Phase 3

A Study of SHR-A1811 in Subjects With Ovarian Cancer

Recruiting
NCT07528898Phase 2

Neoadjuvant SHR-A1811 Combined With Pertuzumab in HER2-Positive Breast Cancer: An Exploratory Clinical Study.

Not Yet Recruiting
NCT06649331Phase 2

Platform Study of ADC Rechallenge in ADC-treated Metastatic Breast Cancer

Recruiting
NCT05924256Phase 2

A Phase II Study of Advanced Salivary Gland Carcinoma Based on Molecular Typing

Active Not Recruiting
NCT05769010Phase 2

Study of SHR-A1811 in HER2-expression Advanced Breast Cancer With Brain Metastases

Recruiting
NCT07466303Phase 2

Serplulimab Combined With Trastuzumab Rezetecan as Neoadjuvant Therapy for Triple-Negative Breast Cancer

Not Yet Recruiting
NCT07466927Phase 2

Study of Multi-mode Thermal Therapy Combined With Immunotherapy In Patients With HER2-negative Breast Cancer With Liver Metastases

Not Yet Recruiting
NCT07417241Phase 2

SHR-A1811 vs Pyrotinib/Capecitabine in Trastuzumab-Resistant HER2+ Advanced Breast Cancer: A Randomized Study

Not Yet Recruiting
NCT04513223Phase 1

A Phase 1 Study of SHR-A1811 in Patients With Selected HER2 Expressing Tumors

Completed
NCT07382687Phase 3

Famitinib Combined With SHR-A1811, Versus SHR-A1811 for CDK4/6 Inhibitors-resistent Advanced HR+/HER2- Breast Cancer With SNF4 Subtype

Not Yet Recruiting
NCT07377916Not Applicable

Clinical Study of SHR-A1811 Combined With Pertuzumab as Second-Line Therapy in Patients With HER2-Altered Advanced NSCLC

Not Yet Recruiting
NCT07340398Phase 2

Neoadjuvant Trastuzumab-rezetecan Plus Pertuzumab or Nab-Paclitaxel, Carboplatin, Trastuzumab, and Pyrotinib After Suboptimal Response to Neoadjuvant Dual HER2-Targeted Therapy Combined With Chemotherapy in HER2-Positive Early Breast Cancer

Recruiting
NCT06430437Phase 3

A Study of SHR-A1811 in First-line Treatment of Patients With Advanced or Metastatic Non-small Cell Lung Cancer With HER2 Mutations

Recruiting
NCT07317778Phase 2

Chemotherapy With or Without Adebrelimab and T-DXh as Neoadjuvant Therapy for HR+/HER2 Low Early Stage Breast Cancer

Not Yet Recruiting
NCT07309770Phase 2

Trastuzumab Rezetecan in Advanced Solid Tumors Refractory to Standard Therapies

Recruiting
NCT07305246Phase 2

Clinical Study of SHR-A1811 With or Without Letrozole in Neoadjuvant Therapy for Early-Stage HR-Positive, HER2-Low Breast Cancer

Not Yet Recruiting
NCT05076682Phase 2

Reverse Triple Negative Immune Resistant Breast Cancer

Recruiting
NCT06840002Phase 1

A Clinical Study of SHR-A1811 Combined With Chemotherapy for Platinum Sensitive Recurrent Ovarian Cancer

Recruiting
NCT07177950Phase 1

A Two-cohort Study of SHR-A1811 in the Treatment of HER2-positive Breast Cancer With Brain Metastases

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
45