Success Metrics

Clinical Success Rate
100.0%

Based on 3 completed trials

Completion Rate
100%(3/3)
Active Trials
25(54%)
Results Posted
0%(0 trials)

Phase Distribution

Ph phase_1
10
22%
Ph not_applicable
1
2%
Ph phase_2
26
57%
Ph phase_3
9
20%

Phase Distribution

10

Early Stage

26

Mid Stage

9

Late Stage

Phase Distribution46 total trials
Phase 1Safety & dosage
10(21.7%)
Phase 2Efficacy & side effects
26(56.5%)
Phase 3Large-scale testing
9(19.6%)
N/ANon-phased studies
1(2.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

3 of 3 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

25

trials recruiting

Total Trials

46

all time

Status Distribution
Active(42)
Completed(3)
Other(1)

Detailed Status

Recruiting17
Not yet recruiting17
Active, not recruiting8
Completed3
unknown1

Development Timeline

Analytics

Development Status

Total Trials
46
Active
25
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 110 (21.7%)
Phase 226 (56.5%)
Phase 39 (19.6%)
N/A1 (2.2%)

Trials by Status

unknown12%
completed37%
active_not_recruiting817%
recruiting1737%
not_yet_recruiting1737%

Recent Activity

Clinical Trials (46)

Showing 20 of 46 trialsScroll for more
NCT05814354Phase 3

SHR-A1811 Versus Investigator's Chemotherapy in Recurrent/Metastatic Breast Cancer Clinical Trial

Active Not Recruiting
NCT06413745Phase 2

Phase II Clinical Study of SHR-A1811 in Patients With HER2 Expression / Amplification of Locally Advanced Unresectable or Recurrent Metastatic Biliary Tract Cancer

Active Not Recruiting
NCT06433609Phase 2

Study of ADCs Combined With Adebrelimab in HER2-negative Advanced Breast Cancer

Recruiting
NCT06126640Phase 3

A Phase III, Active-Controlled Study of SHR-A1811 Versus Trastuzumab Emtansine (T-DM1) in HER2-Positive Primary Breast Cancer Participants With Residual Invasive Disease Following Neoadjuvant Therapy

Active Not Recruiting
NCT07560475Phase 2

Exploratory Study of SHR-A1811 Via Different Administration Routes in Patients

Not Yet Recruiting
NCT07618923Phase 2

Neoadjuvant Dalpiciclib + AI → SHR-A1811 for HR+/HER2-Low Breast Cancer

Not Yet Recruiting
NCT06710990Phase 1

Investigation of Drug-drug Interaction of Ritonavir and Itraconazole on the Pharmacokinetics of SHR-A1811 in Subjects With HER2-expressing Advanced Breast Cancer

Completed
NCT05582499Phase 2

Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy

Recruiting
NCT06828354Phase 3

A Study of SHR-A1811 in Subjects With Ovarian Cancer

Recruiting
NCT07528898Phase 2

Neoadjuvant SHR-A1811 Combined With Pertuzumab in HER2-Positive Breast Cancer: An Exploratory Clinical Study.

Not Yet Recruiting
NCT06649331Phase 2

Platform Study of ADC Rechallenge in ADC-treated Metastatic Breast Cancer

Recruiting
NCT05924256Phase 2

A Phase II Study of Advanced Salivary Gland Carcinoma Based on Molecular Typing

Active Not Recruiting
NCT05769010Phase 2

Study of SHR-A1811 in HER2-expression Advanced Breast Cancer With Brain Metastases

Recruiting
NCT07466303Phase 2

Serplulimab Combined With Trastuzumab Rezetecan as Neoadjuvant Therapy for Triple-Negative Breast Cancer

Not Yet Recruiting
NCT07466927Phase 2

Study of Multi-mode Thermal Therapy Combined With Immunotherapy In Patients With HER2-negative Breast Cancer With Liver Metastases

Not Yet Recruiting
NCT07417241Phase 2

SHR-A1811 vs Pyrotinib/Capecitabine in Trastuzumab-Resistant HER2+ Advanced Breast Cancer: A Randomized Study

Not Yet Recruiting
NCT04513223Phase 1

A Phase 1 Study of SHR-A1811 in Patients With Selected HER2 Expressing Tumors

Completed
NCT07382687Phase 3

Famitinib Combined With SHR-A1811, Versus SHR-A1811 for CDK4/6 Inhibitors-resistent Advanced HR+/HER2- Breast Cancer With SNF4 Subtype

Not Yet Recruiting
NCT07377916Not Applicable

Clinical Study of SHR-A1811 Combined With Pertuzumab as Second-Line Therapy in Patients With HER2-Altered Advanced NSCLC

Not Yet Recruiting
NCT07340398Phase 2

Neoadjuvant Trastuzumab-rezetecan Plus Pertuzumab or Nab-Paclitaxel, Carboplatin, Trastuzumab, and Pyrotinib After Suboptimal Response to Neoadjuvant Dual HER2-Targeted Therapy Combined With Chemotherapy in HER2-Positive Early Breast Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
46