Success Metrics

Clinical Success Rate
100.0%

Based on 3 completed trials

Completion Rate
100%(3/3)
Active Trials
25(52%)
Results Posted
0%(0 trials)

Phase Distribution

Ph not_applicable
1
2%
Ph phase_1
10
21%
Ph phase_3
9
19%
Ph phase_2
28
58%

Phase Distribution

10

Early Stage

28

Mid Stage

9

Late Stage

Phase Distribution48 total trials
Phase 1Safety & dosage
10(20.8%)
Phase 2Efficacy & side effects
28(58.3%)
Phase 3Large-scale testing
9(18.8%)
N/ANon-phased studies
1(2.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

3 of 3 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

25

trials recruiting

Total Trials

48

all time

Status Distribution
Active(44)
Completed(3)
Other(1)

Detailed Status

Not yet recruiting19
Recruiting17
Active, not recruiting8
Completed3
unknown1

Development Timeline

Analytics

Development Status

Total Trials
48
Active
25
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 110 (20.8%)
Phase 228 (58.3%)
Phase 39 (18.8%)
N/A1 (2.1%)

Trials by Status

not_yet_recruiting1940%
recruiting1735%
completed36%
unknown12%
active_not_recruiting817%

Recent Activity

Clinical Trials (48)

Showing 20 of 48 trialsScroll for more
NCT07856303Phase 2

SHR-A1811 Versus Trastuzumab Plus Pertuzumab in ctDNA-Positive HER2-Positive Early Breast Cancer After Pathologic Complete Response

Not Yet Recruiting
NCT06840002Phase 1

A Clinical Study of SHR-A1811 Combined With Chemotherapy for Platinum Sensitive Recurrent Ovarian Cancer

Recruiting
NCT06649331Phase 2

Platform Study of ADC Rechallenge in ADC-treated Metastatic Breast Cancer

Recruiting
NCT07787338Phase 2

SHR-A1811 Monotherapy or Sequential THPy as Neoadjuvant Therapy for Stage II-III HER2-Positive Breast Cancer

Not Yet Recruiting
NCT05814354Phase 3

SHR-A1811 Versus Investigator's Chemotherapy in Recurrent/Metastatic Breast Cancer Clinical Trial

Active Not Recruiting
NCT06413745Phase 2

Phase II Clinical Study of SHR-A1811 in Patients With HER2 Expression / Amplification of Locally Advanced Unresectable or Recurrent Metastatic Biliary Tract Cancer

Active Not Recruiting
NCT06433609Phase 2

Study of ADCs Combined With Adebrelimab in HER2-negative Advanced Breast Cancer

Recruiting
NCT06126640Phase 3

A Phase III, Active-Controlled Study of SHR-A1811 Versus Trastuzumab Emtansine (T-DM1) in HER2-Positive Primary Breast Cancer Participants With Residual Invasive Disease Following Neoadjuvant Therapy

Active Not Recruiting
NCT07618923Phase 2

Neoadjuvant Dalpiciclib + AI → SHR-A1811 for HR+/HER2-Low Breast Cancer

Not Yet Recruiting
NCT07560475Phase 2

Exploratory Study of SHR-A1811 Via Different Administration Routes in Patients

Not Yet Recruiting
NCT06710990Phase 1

Investigation of Drug-drug Interaction of Ritonavir and Itraconazole on the Pharmacokinetics of SHR-A1811 in Subjects With HER2-expressing Advanced Breast Cancer

Completed
NCT05582499Phase 2

Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy

Recruiting
NCT06828354Phase 3

A Study of SHR-A1811 in Subjects With Ovarian Cancer

Recruiting
NCT07528898Phase 2

Neoadjuvant SHR-A1811 Combined With Pertuzumab in HER2-Positive Breast Cancer: An Exploratory Clinical Study.

Not Yet Recruiting
NCT05924256Phase 2

A Phase II Study of Advanced Salivary Gland Carcinoma Based on Molecular Typing

Active Not Recruiting
NCT05769010Phase 2

Study of SHR-A1811 in HER2-expression Advanced Breast Cancer With Brain Metastases

Recruiting
NCT07466303Phase 2

Serplulimab Combined With Trastuzumab Rezetecan as Neoadjuvant Therapy for Triple-Negative Breast Cancer

Not Yet Recruiting
NCT07466927Phase 2

Study of Multi-mode Thermal Therapy Combined With Immunotherapy In Patients With HER2-negative Breast Cancer With Liver Metastases

Not Yet Recruiting
NCT07417241Phase 2

SHR-A1811 vs Pyrotinib/Capecitabine in Trastuzumab-Resistant HER2+ Advanced Breast Cancer: A Randomized Study

Not Yet Recruiting
NCT04513223Phase 1

A Phase 1 Study of SHR-A1811 in Patients With Selected HER2 Expressing Tumors

Completed

Drug Details

Intervention Type
DRUG
Total Trials
48