Success Metrics

Clinical Success Rate
76.9%

Based on 10 completed trials

Completion Rate
77%(10/13)
Active Trials
14(44%)
Results Posted
50%(5 trials)
Terminated
3(9%)

Phase Distribution

Ph phase_1
13
41%
Ph phase_2
6
19%
Ph phase_4
9
28%
Ph early_phase_1
1
3%
Ph phase_3
2
6%

Phase Distribution

14

Early Stage

6

Mid Stage

11

Late Stage

Phase Distribution31 total trials
Early Phase 1First-in-human
1(3.2%)
Phase 1Safety & dosage
13(41.9%)
Phase 2Efficacy & side effects
6(19.4%)
Phase 3Large-scale testing
2(6.5%)
Phase 4Post-market surveillance
9(29.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.9%

10 of 13 finished

Non-Completion Rate

23.1%

3 ended early

Currently Active

14

trials recruiting

Total Trials

32

all time

Status Distribution
Active(18)
Completed(10)
Terminated(3)
Other(1)

Detailed Status

Completed10
Recruiting7
Active, not recruiting7
Not yet recruiting3
Terminated3
unknown1

Development Timeline

Analytics

Development Status

Total Trials
32
Active
14
Success Rate
76.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (3.2%)
Phase 113 (41.9%)
Phase 26 (19.4%)
Phase 32 (6.5%)
Phase 49 (29.0%)

Trials by Status

not_yet_recruiting39%
terminated39%
recruiting722%
unknown13%
active_not_recruiting722%
completed1031%
enrolling_by_invitation13%

Recent Activity

Clinical Trials (32)

Showing 20 of 32 trialsScroll for more
NCT04128189Phase 3

Shingrix in Renal Transplant Recipients

Recruiting
NCT06375512Phase 1

A Study to Describe the Safety, Reactogenicity, and Immunogenicity of Herpes Zoster IN001 mRNA Vaccine (IN001) in Healthy Participants

Completed
NCT05703607Phase 1

A Study to Learn About a Modified RNA Vaccine Against Shingles in Healthy Adults

Terminated
NCT07481604Phase 2

Safety and Immunogenicity of CVI-VZV-001 in Adults Aged 50 Years and Above

Not Yet Recruiting
NCT05580458Phase 1

Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population

Recruiting
NCT05170399Phase 4

Vaccine Responses in Patients With B Cell Malignancies

Recruiting
NCT07285265Phase 1

Phase I Clinical Trial of Lyophilized Herpes Zoster mRNA Vaccine in Adults Aged 40 Years or Above

Active Not Recruiting
NCT06569823Phase 1

Safety and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adults 50 Years of Age and Over

Recruiting
NCT07205796Phase 2

A Phase 2 Study to Describe the Safety, Reactogenicity, and Immunogenicity of Herpes Zoster IN001 mRNA Vaccine (IN001) in Healthy Participants

Not Yet Recruiting
NCT05304351Phase 2

Safety and Immunogenicity of CRV-101 Vaccine for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older

Active Not Recruiting
NCT05701800Phase 1

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1468 in Healthy Adults ≥50 Years of Age

Active Not Recruiting
NCT06409494Phase 1

Clinical Trial to Evaluate EuHZV in Healthy Adults Aged 50 to 69 Years

Active Not Recruiting
NCT05550194Phase 4

VZV in the Enteric Nervous System: Pathogenesis and Consequences

Recruiting
NCT04403139Phase 4

VZV-specific Tissue Resident Memory T-cells After Shingrix Vaccination

Active Not Recruiting
NCT03798691Phase 4

Immunogenicity of Herpes Zoster Subunit Vaccine in Inflammatory Bowel Disease Patients Treated With Vedolizumab

Completed
NCT06581575Phase 2

A Phase 2 Study to Evaluate JCXH-105, an srRNA-based Herpes Zoster Vaccine

Active Not Recruiting
NCT06335849Phase 1

A Safety and Immunogenicity Trial of the Recombinant Zoster Vaccine (CHO Cell), LYB004 in Adults Aged 50 to 70 Years

Active Not Recruiting
NCT03591770Phase 4

Shingrix Vaccine in Patients With Moderate to Severe Ulcerative Colitis on Tofacitinib

Terminated
NCT03953196Early Phase 1

A Study Exploring the Use of Vaccine and Antigen Challenges for Immune Monitoring in Healthy Participants

Completed
NCT06801509Phase 1

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Recombinant Herpes Zoster Vaccine

Not Yet Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
32