Success Metrics

Clinical Success Rate
90.9%

Based on 20 completed trials

Completion Rate
91%(20/22)
Active Trials
2(8%)
Results Posted
35%(7 trials)
Terminated
2(8%)

Phase Distribution

Ph phase_2
5
21%
Ph phase_3
7
29%
Ph phase_1
12
50%

Phase Distribution

12

Early Stage

5

Mid Stage

7

Late Stage

Phase Distribution24 total trials
Phase 1Safety & dosage
12(50.0%)
Phase 2Efficacy & side effects
5(20.8%)
Phase 3Large-scale testing
7(29.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

90.9%

20 of 22 finished

Non-Completion Rate

9.1%

2 ended early

Currently Active

2

trials recruiting

Total Trials

24

all time

Status Distribution
Active(2)
Completed(20)
Terminated(2)

Detailed Status

Completed20
Recruiting2
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
24
Active
2
Success Rate
90.9%
Most Advanced
Phase 3

Trials by Phase

Phase 112 (50.0%)
Phase 25 (20.8%)
Phase 37 (29.2%)

Trials by Status

recruiting28%
completed2083%
terminated28%

Recent Activity

Clinical Trials (24)

Showing 20 of 24 trialsScroll for more
NCT06894212Phase 3

A Trial of the Efficacy and Safety of SEP-363856 in Acutely Psychotic Participants With Schizophrenia

Recruiting
NCT05593029Phase 2

A Trial of the Safety and Efficacy of SEP-363856 in the Treatment of Adults With Major Depressive Disorder

Completed
NCT07225712Phase 3

A Long-term Administration Trial of SEP-363856 in Patients With Schizophrenia

Recruiting
NCT04115319Phase 3

A Study of the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia.

Completed
NCT05628103Phase 3

A Clinical Study That Will Evaluate How Well SEP-363856 Works and How Safe it is in People With Schizophrenia That Switch to SEP-363856 From Their Current Antipsychotic Medication

Completed
NCT05741528Phase 3

An Extension Study to a Clinical Study That Will Continue to Evaluate the Effectiveness and Safety of SEP-363856 in People With Schizophrenia That Switch to SEP-363856 From Their From Their Current Antipsychotic Medication

Completed
NCT05729373Phase 2

A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder

Completed
NCT05359081Phase 3

A Clinical Trial to Evaluate the Long-term Safety and Tolerability of SEP-363856 in Patients With Schizophrenia in Japan

Terminated
NCT04038957Phase 1

A Clinical Study to Investigate the Effect of an Investigational Drug as an Added Medication to an Antipsychotic, in Adults With Schizophrenia, as Measured Positron Emission Tomography (PET) Imaging

Completed
NCT04109950Phase 3

A Clinical Study to Evaluate the Long-term Safety and Tolerability of an Investigational Drug in People With Schizophrenia

Terminated
NCT02970929Phase 2

An Extension Study of Safety and Tolerability of SEP-363856 in Adult Subjects With Schizophrenia

Completed
NCT02969369Phase 2

A Study to Evaluate the Efficacy, Safety and Tolerability of SEP-363856 in Subjects With Parkinson's Disease Psychosis

Completed
NCT02969382Phase 2

A Study to Evaluate the Efficacy and Safety of SEP-363856 in Acutely Psychotic Adults With Schizophrenia

Completed
NCT05015673Phase 1

This is a Study to Determine the Effect of Multiple Doses of an Investigational Drug, Taken by Mouth, in People With Narcolepsy-cataplexy. Accepting Both Males and Females Ages of 18 Years to 55 Years. This Study Will be Conducted in the US and Will Require Approximately 13 Weeks Participation.

Completed
NCT05463770Phase 1

A Clinical Study That Will Assess the Effect of SEP-363856 and Prior Antipsychotic (PA) Standard of Care on Glucose and Regulation of Insulin in Patients With Schizophrenia

Completed
NCT01940159Phase 1

A Study Assessing the Safety, Tolerability, and Pharmacokinetics of SEP-363856 in Male and Female Subjects With Schizophrenia

Completed
NCT01972711Phase 1

Study Assessing SEP-363856 in Male and Female Volunteers With High or Low Schizotype Characteristics

Completed
NCT05542264Phase 1

A Clinical Study That Will Assess the Effect of SEP-363856 or Prior Antipsychotic (PA) Standard of Care on Body-weight Associated Parameters in Subjects With Schizophrenia

Completed
NCT04865835Phase 1

A Clinical Trial Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the Drug Metformin Travels Through the Body in People With Schizophrenia.

Completed
NCT05402111Phase 1

A Clinical Study That Will Assess How Food Moves Through the Stomach and Effects Blood Glucose Levels in Subjects With Schizophrenia Taking SEP-363856 or and Prior Antipsychotic (PA) Standard

Completed

Drug Details

Intervention Type
DRUG
Total Trials
24