Success Metrics

Clinical Success Rate
100.0%

Based on 4 completed trials

Completion Rate
100%(4/4)
Active Trials
7(64%)
Results Posted
125%(5 trials)

Phase Distribution

Ph phase_1
1
9%
Ph phase_2
7
64%
Ph phase_3
3
27%

Phase Distribution

1

Early Stage

7

Mid Stage

3

Late Stage

Phase Distribution11 total trials
Phase 1Safety & dosage
1(9.1%)
Phase 2Efficacy & side effects
7(63.6%)
Phase 3Large-scale testing
3(27.3%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

4 of 4 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

7

trials recruiting

Total Trials

11

all time

Status Distribution
Active(7)
Completed(4)

Detailed Status

Completed4
Active, not recruiting4
Recruiting3

Development Timeline

Analytics

Development Status

Total Trials
11
Active
7
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 11 (9.1%)
Phase 27 (63.6%)
Phase 33 (27.3%)

Trials by Status

completed436%
recruiting327%
active_not_recruiting436%

Recent Activity

Clinical Trials (11)

Showing 11 of 11 trials
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT05554328Phase 2

Testing the Use of the Combination of Selumetinib and Olaparib or Selumetinib Alone Targeted Treatment for RAS Pathway Mutant Recurrent or Persistent Ovarian and Endometrial Cancers, A ComboMATCH Treatment Trial

Recruiting
NCT03155620Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Active Not Recruiting
NCT04166409Phase 3

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Recruiting
NCT04576117Phase 3

A Study to Compare Treatment With the Drug Selumetinib Alone Versus Selumetinib and Vinblastine in Patients With Recurrent or Progressive Low-Grade Glioma

Active Not Recruiting
NCT01364051Phase 1

Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies

Active Not Recruiting
NCT03871257Phase 3

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

Active Not Recruiting
NCT03213691Phase 2

Selumetinib Sulfate in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Completed
NCT02839720Phase 2

Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma

Completed
NCT03040986Phase 2

Selumetinib Sulfate in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer With KRAS G12R Mutations

Completed
NCT00551070Phase 2

Selumetinib Sulfate in Treating Woman With Recurrent Low-Grade Ovarian Cancer or Peritoneum Cancer

Completed

All 11 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
11