Selumetinib
Selumetinib is a pharmaceutical drug with 75 clinical trials. Currently 18 active trials ongoing. Historical success rate of 79.2%.
Success Metrics
Based on 38 completed trials
Phase Distribution
Phase Distribution
33
Early Stage
38
Mid Stage
3
Late Stage
Highest Phase Reached
Phase 3Trial Status & Enrollment
74.5%
38 of 51 finished
25.5%
13 ended early
18
trials recruiting
75
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer
Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a (Trastuzumab Deruxtecan), for Advanced Pancreatic Ductal Adenocarcinoma
Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas
Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies
Clinical Trials (75)
Open-Label, Randomised, Multi-Drug, Biomarker-Directed, Phase 1b Study in Pts w/ Muscle Invasive Bladder Cancer
Testing the Combination of Anti-Cancer Drugs, Selumetinib and DS-8201a (Trastuzumab Deruxtecan), for Advanced Pancreatic Ductal Adenocarcinoma
Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas
Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies
Phase I Study to Assess the Effect of Food on the PK and Gastrointestinal Tolerability of Selumetinib in Adolescent Children With Neurofibromatosis Type 1 Related Plexiform Neurofibromas
A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)
A Phase 2 Study of Osimertinib in Combination With Selumetinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer
Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer
Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST
Assess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLC
Selumetinib for NF2-Related Schwannomatosis
European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors
A Study of Different Dosing Schedules of Selumetinib With Cisplatin/Gemcitabine (CIS/GEM) Versus CIS/GEM Alone in Biliary Cancer
Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1
SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors
National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer
Selumetinib and Olaparib in Solid Tumors
Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas
AMTEC IIT: Phase 2 Multiarm Study in TNBC
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 75