sapropterin dihydrochloride
sapropterin dihydrochloride is a pharmaceutical drug with 17 clinical trials. Currently 1 active trials ongoing. Historical success rate of 100.0%.
Success Metrics
Based on 13 completed trials
Phase Distribution
Phase Distribution
1
Early Stage
6
Mid Stage
5
Late Stage
Highest Phase Reached
Phase 3Trial Status & Enrollment
86.7%
13 of 15 finished
13.3%
2 ended early
1
trials recruiting
17
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
PD-1 Antibody and Sapropterin Dihydrochloride in Patients With PDAC
Evaluation of Behavior, Executive Function, Neurotransmitter Function and Genomic Expression Kuvan Nonresponders
L-arginine Study for Persistent Symptoms of Schizophrenia
A Phase 1 Study to Evaluate Effects of Sapropterin Dihydrochloride on QTc Intervals in Healthy Adult Subjects
A Phase 2, Pharmacokinetic (PK) Study of 6R-BH4 Alone or 6R-BH4 With Vitamin C in Subjects With Endothelial Dysfunction
Clinical Trials (17)
PD-1 Antibody and Sapropterin Dihydrochloride in Patients With PDAC
Evaluation of Behavior, Executive Function, Neurotransmitter Function and Genomic Expression Kuvan Nonresponders
L-arginine Study for Persistent Symptoms of Schizophrenia
A Phase 1 Study to Evaluate Effects of Sapropterin Dihydrochloride on QTc Intervals in Healthy Adult Subjects
A Phase 2, Pharmacokinetic (PK) Study of 6R-BH4 Alone or 6R-BH4 With Vitamin C in Subjects With Endothelial Dysfunction
A Phase 2 Study of the Effects of 6R-BH4 in Subjects With Sickle Cell Disease
A Phase 2 Study of the Effects of Sapropterin Dihydrochloride on Symptomatic Peripheral Arterial Disease
Effect of Kuvan on Neurocognitive Function, Blood Phenylalanine Level, Safety, and Pharmacokinetics in Children With PKU
Impact of KUVAN® on Gastric Relaxation in Women With Diabetic Gastroparesis.
Safety and Therapeutic Effects of Sapropterin Dihydrochloride on Neuropsychiatric Symptoms in Phenylketonuria (PKU) Patients
Study of Phenoptin to Increase Phenylalanine Tolerance in Phenylketonuric Children on a Phenylalanine-restricted Diet
Neuroimaging and Neurocognitive Assessment and Response to Sapropterin Dihydrochloride Treatment in Phenylketonuria
Tetrahydrobiopterin Treatment in Children With Idiopathic Cognitive Developmental Disorders
Study of Phenoptin in Subjects With Phenylketonuria Who Participated in Protocols PKU-004 or PKU-006
A Phase 3, Multicenter, Open-Label Extension Study of Phenoptin in Subjects With PKU Who Have Elevated Phenylalanine Levels
Sapropterin Expanded Access Program
Study to Evaluate the Response to and Safety of an 8-Day Course of Phenoptin™ Treatment in Subjects With Phenylketonuria
All 17 trials loaded
Drug Details
- Intervention Type
- DRUG
- Total Trials
- 17